NCT06191198

Communication Bridge 3 Study

Communication Bridge: Optimizing an Evidence-based Intervention for Individuals With Primary Progressive Aphasia

• Status: Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: University of Chicago · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

This study will use a randomized controlled trial design to evaluate the effect of two evidence-based treatments for adults with mild-moderate Primary Progressive Aphasia (PPA). The aim of the study is to help us better understand the effects of speech-language therapy on communication abilities in individuals with PPA.

Detailed description

Participants with a diagnosis of PPA and their actively-engaged care partners will be involved in the study for approximately 17 months. Each participant will receive a laptop equipped with the necessary applications and features for the study. Participants will receive up to 10 evaluations and 20 speech therapy sessions with a licensed speech therapist, as well as access to Communication Bridge, a personalized web application to practice home exercises that reinforce treatment strategies. There are no costs to participate in this study.

Conditions

• Primary Progressive Aphasia

Interventions

Type	Name	Description
BEHAVIORAL	Communication Bridge™	Evidence-based speech language therapy treatment will be compared and contrasted in the two arms of the study.
BEHAVIORAL	Evidence-Based Impairment Focused	Evidence-based speech language therapy treatment will be compared and contrasted in the two arms of the study.

Timeline

• Start date: 2024-08-23
• Primary completion: 2028-07-15
• Completion: 2028-07-15
• First posted: 2024-01-05
• Last updated: 2025-05-30

Locations

1 site across 1 country: United States