| Recruiting | Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid Tumors NCT07444723 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 / Phase 3 |
| Not Yet Recruiting | Aldosterone Variations in Patients With Primary Hyperparathyroidism After Surgery NCT07388914 | Central Hospital, Nancy, France | — |
| Not Yet Recruiting | Is Intraoperative PTH Monitoring Obsolete in Times of Choline PET/CT? a Prospective Multicenter Cohort Study t NCT06804681 | University of Zurich | — |
| Recruiting | Bisphosphonate Prior to Parathyroidectomy in Primary Hyperparathyroidism NCT06859580 | University of Aarhus | Phase 4 |
| Not Yet Recruiting | Diagnostic Performance of [11C]Choline PET/CT In the Preoperative Assessment of Primary Hyperparathyroidism NCT06647966 | IRCCS San Raffaele | — |
| Completed | Upfront Ultrasound for Preoperative Localization in Primary Hyperparathyroidism NCT07068867 | Odense University Hospital | — |
| Recruiting | Parathyroid Tumor Clonal Status NCT05997810 | Washington University School of Medicine | — |
| Active Not Recruiting | Glycemic Control, Type II Diabetes, Parathyroidectomy NCT05761743 | The Cleveland Clinic | — |
| Recruiting | 18F-choline Positron-emission-tomography - Computed-tomography Compared to Conventional Imaging for Localizing NCT07138820 | Region Skane | N/A |
| Recruiting | Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients NCT06523582 | Universidad Nacional Autonoma de Mexico | — |
| Completed | Object Assessment of Improvement in Non-Specific Symptoms After Parathyroidectomy for Primary Hyperparathyroid NCT06337825 | The Cleveland Clinic | — |
| Completed | Evaluating Impact of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands Durin NCT05022641 | University of Michigan | N/A |
| Recruiting | Natural History Study of Parathyroid Disorders NCT04969926 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |
| Completed | Gait and Balance Parameters Before and After Parathyroidectomy in Patients With Primary Hyperparathyroidism NCT03713671 | Recep Tayyip Erdogan University Training and Research Hospital | N/A |
| Completed | Evaluating Impact of NIRAF Detection for Identifying Parathyroid Glands During Parathyroidectomy NCT04299425 | Vanderbilt-Ingram Cancer Center | N/A |
| Completed | Preoperative Localization Strategies in Primary Hyperparathyroidism NCT04305561 | Odense University Hospital | N/A |
| Recruiting | Calcitonin Pre-treatment to Improve SPECT-CT Sensitivity NCT03935984 | Joseph Sferra | Phase 4 |
| Unknown | Osteoporosis in Primary Hyperparathyroidism NCT04085419 | University Medical Centre Ljubljana | Phase 4 |
| Completed | Vitamin D Metabolism in Patients With Endocrine Disorders NCT04844164 | Endocrinology Research Centre, Moscow | Phase 1 |
| Completed | The Crosstalk Between Calcium-sensing Receptor Signaling and Endocannabinoid System in Primary Hyperparathyroi NCT03831620 | Insel Gruppe AG, University Hospital Bern | — |
| Unknown | Feasibility of Parathyroidectomy With Exploration of 4 Parathyroid Glands in Outpatients NCT03732157 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Circulating miRNA in Primary Hyperparathyroidism NCT03931109 | University of Pennsylvania | — |
| Unknown | Comparison of Cervical Ultrasound and Echoscintigraphy for Preoperative Localization Diagnosis in Primary Hype NCT03605472 | CHU de Reims | N/A |
| Completed | Phase 3 Study of KHK7580 for the Treatment of Hypercalcemia in Patients With Parathyroid Carcinoma or Primary NCT03280264 | Kyowa Kirin Co., Ltd. | Phase 3 |
| Completed | Treatment of Primary Hyperparathyroidism With Denosumab and Cinacalcet. NCT03027557 | Peter Vestergaard | Phase 3 |
| Completed | Effect of Parathyroidectomy on Cardiovascular Health NCT02989428 | University of Aarhus | N/A |
| Completed | Omission of Intact Parathyroid Hormone Testing During Surgery in Treating Patients With Primary Hyperparathyro NCT03011736 | Roswell Park Cancer Institute | N/A |
| Completed | Optimization and Individualization of Diagnostic Scintigraphy Protocol and Minimally Invasive Radio-guided Par NCT04344886 | University Hospital Ostrava | N/A |
| Recruiting | Cohort Primary Hyperparathyroidism NCT05469087 | Nantes University Hospital | — |
| Completed | Effect of Mechanical Loading on vBMD and Geometry in Patients With Primary Hyperparathyroidism NCT05426512 | EFSTATHIOS CHRONOPOULOS | — |
| Completed | Evaluating Alternative Medical Therapies in Primary Hyperparathyroidism NCT02525796 | Brigham and Women's Hospital | Phase 2 / Phase 3 |
| Recruiting | Molecular and Immunohistochemical Profiling of Tumors in Patients With Parathyroid Tumors NCT03039439 | M.D. Anderson Cancer Center | — |
| Completed | A Retrospective Analysis of the Diagnostic Performance of 11C-choline PET/CT in Primary Hyperparathyroidism NCT04608253 | University Medical Center Groningen | — |
| Completed | Preliminary Study Concerning the Validity of Parathyroid Exploration on a CZT Camera NCT02854345 | Centre Hospitalier Universitaire de Besancon | N/A |
| Unknown | Percent Change in Baseline Bone Mineral Density (BMD) After Parathyroidectomy in Patients With Primary Hyperpa NCT03052075 | M.D. Anderson Cancer Center | — |
| Completed | Primary Hyperparathyroidism: Short-term Calcimimetics Treatment - Relevance for Parathyroid Surgery Decisions? NCT02227264 | Karolinska University Hospital | N/A |
| Unknown | 11C Methionine PET for the Detection of Hyperfunctional Parathyroid Tissues NCT01783002 | University of British Columbia | Phase 2 |
| Terminated | Cohort Trial on Perioperative Localization Techniques of Parathyroid Adenomas NCT04013100 | IHU Strasbourg | — |
| Completed | EC17 for Intraoperative Imaging for Parathyroidectomy NCT01996072 | University of Pennsylvania | Phase 1 |
| Recruiting | Amino Acid Transporter System PET/CT Imaging in AATS-Related Diseases NCT07379463 | Tianjin Medical University | — |
| Unknown | Differentially Expressed Proteins in Sporadic Parathyroid Tumors NCT01647503 | Post Graduate Institute of Medical Education and Research, Chandigarh | — |
| Completed | Near Infrared Fluorescent Imaging in Thyroid and Parathyroid Surgery With the Fluobeam(TM) System of Fluoptics NCT01598727 | Sheffield Teaching Hospitals NHS Foundation Trust | Phase 1 |
| Completed | Bone Architectural Parameters in Postmenopausal Women Affected With Primary Hyperparathyroidism NCT02539498 | Assistance Publique - Hôpitaux de Paris | N/A |
| Terminated | Denosumab in Primary Hyperparathyroidism NCT01558115 | Columbia University | Phase 4 |
| Completed | An Intra-individual Titration Study of KRN1493 for the Treatment of Hypercalcemia in Patients With Parathyroid NCT01460030 | Kyowa Kirin Co., Ltd. | Phase 3 |
| Completed | Vitamin D Repletion in Primary Hyperparathyroidism NCT01306656 | Columbia University | Phase 4 |
| Completed | Systematic Treatment After Successful Surgical Treatment for Primary Hyperparathyroidism With Strontium Ranela NCT01222026 | Medical University of Vienna | Phase 4 |
| Completed | Surgery for Primary Hyperparathyroidism (pHPT) in Patients Older Than 65 Years Compared With Follow-up NCT01087619 | Region Skane | N/A |
| Completed | The Midwest Head and Neck Cancer Consortium Multi-Institutional Parathyroid Registry NCT01409798 | University of Nebraska | — |
| Withdrawn | Primary Hyperparathyroidism (PHPT): Early Effect of Vitamin D NCT01329666 | Columbia University | Phase 2 / Phase 3 |
| Completed | Radius Loading in Primary Hyperparathyroidism NCT01571843 | Columbia University | N/A |
| Unknown | Impact of Parathyroidectomy on Renal Function NCT04798092 | Central Hospital, Nancy, France | — |
| Terminated | Lipids Profile in Primary Hyperparathyroidism NCT00961701 | HaEmek Medical Center, Israel | — |
| Unknown | Primary Hyperparathyroidism: Does a Systematic Treatment Improve the Calcium and Bone Metabolism After Surgery NCT00973336 | Medical University of Vienna | Phase 2 |
| Completed | OPG/Soluble RANKL (sRANKL) and Bone Mineral Density in Primary Hyperparathyroidism NCT01889134 | Wroclaw Medical University | N/A |
| Completed | Effect of Vitamin D Treatment in Primary Hyperparathyroidism NCT00674154 | University of Aarhus | Phase 2 / Phase 3 |
| Completed | Vitamin D Supplementation After Parathyroid Surgery NCT00982722 | Karolinska University Hospital | N/A |
| Completed | Surgical Outcomes in Patients With Primary Hyperparathyroidism and Unclear Preoperative Localisation Studies NCT04740502 | University of Cagliari | N/A |
| Completed | Evaluation of Non Specific Symptoms and Quality of Life Before and After Surgery for Mild Primary Hyperparathy NCT01776502 | Nantes University Hospital | — |
| Completed | Primary Hyperparathyroidism: Non-classical Manifestations NCT00432939 | Columbia University | — |
| Completed | Effects of Parathyroidectomy on Cardiovascular Risk Factors in Primary Hyperparathyroidism NCT01057732 | HaEmek Medical Center, Israel | — |
| Completed | Open Versus Video-Assisted Minimal-Invasive Parathyroid Surgery NCT00877981 | Uppsala University | N/A |
| Completed | Safety, Tolerability, and Clinical Effects of Twice-daily Doses of Cinacalcet (AMG 073) in Adults With Primary NCT03776058 | Amgen | Phase 2 |
| Completed | Asymptomatic Primary Hyperparathyroidism: A Prospective, Randomized Trial NCT00522028 | Oslo University Hospital | — |
| Completed | Safety, Pharmacokinetics, and Clinical Effects of Cinacalcet (AMG 073) in Primary Hyperparathyroidism NCT03774771 | Amgen | Phase 2 |
| Completed | Minimally Invasive Radioguided Parathyroidectomy NCT01530919 | University of Louisville | — |