Trials / Recruiting
RecruitingNCT03039439
Molecular and Immunohistochemical Profiling of Tumors in Patients With Parathyroid Tumors
Molecular and Immunohistochemical Profiling of Tumor From Patients With Parathyroid Tumors for Evaluation of Targeted Agents
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 310 (estimated)
- Sponsor
- M.D. Anderson Cancer Center · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
This trial studies molecular and immunohistochemical profiling of tumors in patients with parathyroid tumors. Studying molecular and immunohistochemical profiling of tumors may help doctors avoid inconsistencies in diagnosis, unnecessary or incomplete surgery, surgical morbidity, psychological stress, and inadequate follow up.
Detailed description
PRIMARY OBJECTIVES: I. To determine the differences in clinical behavior and immunohistochemical (IHC) biomarkers between parathyroid carcinoma (PC), atypical neoplasm (AN) and parathyroid adenoma (PA). II. To determine which potential genes can be used in patients with parathyroid tumors for diagnostic purposes. OUTLINE: Previously collected tumor tissue and blood samples are analyzed via immunohistochemical profiling for identifying potential genes showing molecular aberrations as other types of cancer.
Conditions
- Parathyroid Gland Adenoma
- Parathyroid Gland Atypical Adenoma
- Parathyroid Gland Carcinoma
- Primary Hyperparathyroidism
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Biospecimen Collection | Previously collected tumor tissue and blood samples |
| OTHER | Laboratory Biomarker Analysis | Correlative studies |
Timeline
- Start date
- 2015-11-24
- Primary completion
- 2028-11-30
- Completion
- 2028-11-30
- First posted
- 2017-02-01
- Last updated
- 2025-11-21
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03039439. Inclusion in this directory is not an endorsement.