| Recruiting | AI-based System for Assessing Suspected Viral Pneumonia Related Lung Changes NCT06501599 | Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department | — |
| Unknown | Diagnostic Accuracy of Pocket-size Lung Ultrasound in Pneumonia Etiology and Complications in Hospitalized Chi NCT06296693 | Centro Hospitalar Universitário de Santo António | N/A |
| Recruiting | Acyclovir in Ventilated Patients With Pneumonia and HSV-1 in BAL NCT06134492 | Jena University Hospital | Phase 3 |
| Completed | Using Probability of Community-Acquired Pneumonia to Tailor Antimicrobials Among Inpatients NCT05976581 | Jonathan Baghdadi | N/A |
| Withdrawn | Valproate Alone or in Combination With Quetiapine for Severe COVID-19 Pneumonia With Agitated Delirium NCT04513314 | University of Miami | Phase 4 |
| Completed | Tobacco Use and the Risk of COVID-19 and Adverse Outcomes NCT05321433 | Karolinska Institutet | — |
| Completed | Comparison Between Different Doses of Steroids in COVID-19 Patients NCT05279482 | Ain Shams University | — |
| Recruiting | Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia. NCT05123755 | Vasomune Therapeutics, Inc. | Phase 2 |
| Withdrawn | COVIDNOCHE Trial (HFNO Versus CPAP Helmet) in COVID-19 Pneumonia NCT04381923 | University of Pennsylvania | N/A |
| Terminated | Cromolyn Sodium for Treatment of COVID-19 Pneumonia NCT05077917 | Texas Tech University Health Sciences Center, El Paso | Phase 3 |
| Completed | Effectiveness of Covid-19 Vaccination in Eswatini Against SARS-CoV-2 Associated Hospitalization and Death NCT04914832 | Shabir Madhi | Phase 4 |
| Completed | Evaluation of Postmortem Pulmonary Interstitial Fibrosis Severity and EGFR Positivity in Covid-19 Pneumonia NCT05290441 | Bursa Yuksek Ihtisas Training and Research Hospital | N/A |
| Terminated | Pediatric Helmet CPAP Pilot Study NCT04764929 | Columbia University | N/A |
| Completed | The Potential Role of sRAGE, KL-6, and SP-D as Prognostic Factors in Children With COVID-19 NCT05619640 | Haseki Training and Research Hospital | — |
| Completed | D-Dimer as Predictor of Disease Outcome in Intensive Care Unit in COVID-19m Patients NCT05279469 | Ain Shams University | — |
| Unknown | DEXamethasone EARLY Administration in Hospitalized Patients With Covid-19 Pneumonia NCT04836780 | Hospital Universitario Infanta Leonor | Phase 3 |
| Completed | Health Communication to Influence COVID-19 Vaccination Intent and Message Propagation NCT05244356 | Clinical Research Centre, Malaysia | N/A |
| Unknown | Hemodynamic Effect of Prone Position in Non-intubated Patient With COVID 19 NCT04834947 | Hospices Civils de Lyon | — |
| Completed | Effect of Respiratory Exerciser on Pulmonary Functions of COVID-19 Patients NCT04826731 | Diskapi Yildirim Beyazit Education and Research Hospital | — |
| Completed | Double-Blind, Randomized, Placebo-Controlled, Multi-Center Phase 3 Study to Evaluate the Efficacy and Safety o NCT04629703 | Rigel Pharmaceuticals | Phase 3 |
| Completed | Assess the Safety and Immunogenicity of NDV-HXP-S Vaccine in Thailand NCT04764422 | Mahidol University | Phase 1 / Phase 2 |
| Completed | A Phase 1/2 Safety and Immunogenicity Trial of COVID-19 Vaccine COVIVAC (Phase 1) NCT04830800 | Institute of Vaccines and Medical Biologicals, Vietnam | Phase 1 |
| Completed | Initial CT Findings and CO-RADS Stage in COVID-19 NCT04789447 | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | — |
| Unknown | Spironolactone and Dexamethasone in Patients Hospitalized With COVID-19 NCT04826822 | Chita State Regional Clinical Hospital Number 1 | Phase 3 |
| Completed | Nebulized Heparin for the Treatment of COVID-19 NCT04723563 | Frederick Health | Phase 4 |
| Completed | Study on Efficacy and Safety of Reparixin in the Treatment of Hospitalized Patients With Severe COVID-19 Pneum NCT04878055 | Dompé Farmaceutici S.p.A | Phase 3 |
| Completed | Diaphragmatic Echography in COVID-19 Pneumonia NCT05805579 | Javier Lázaro | — |
| Unknown | Remdesivir in Adults With Covid-19: Mansoura University Hospital Experience NCT04728880 | Mansoura University | — |
| Completed | Efficacy, Safety, Tolerability, and Biomarkers of Ibudilast (MN-166) in Patients Hospitalized With COVID-19 at NCT04429555 | MediciNova | Phase 2 |
| Withdrawn | Aralast NP With Antiviral Treatment and Standard of Care Versus Antiviral Treatment With Standard of Care in H NCT04675086 | Blessing Corporate Services, Inc | Phase 3 |
| Completed | Antiviral Drugs on the Treatment of SARS-CoV-2 NCT04727775 | Astana Medical University | — |
| Unknown | Steroids and Unfractionated Heparin in Critically Ill Patients With Pneumonia From COVID-19 Infection NCT04528888 | Massimo Girardis | Phase 3 |
| Completed | Inhaled NO for the Treatment of Viral Pneumonia in Adults NCT04606407 | Beyond Air Inc. | N/A |
| Terminated | Biomarkers for Dexamethasone Response in Sars-Cov-2 / COVID-19 Pneumonia NCT04619693 | University Hospital, Montpellier | — |
| Completed | Inhalation Low Dose Radionuclide Therapy in Treatment COVID-19 NCT04724538 | National Medical Research Radiological Centre of the Ministry of Health of Russia | Phase 1 / Phase 2 |
| Completed | Lung Damage Caused by SARS-CoV-2 Pneumonia (COVID-19) NCT04435327 | University of Milano Bicocca | — |
| Unknown | Low Dose Pulmonary Irradiation in Patients With COVID-19 Infection of Bad Prognosis NCT04414293 | Hospital Provincial de Castellon | N/A |
| Completed | Prone Position and Respiratory Outcomes in Non-Intubated COVID-19 PatiEnts The "PRONE" Study NCT04517123 | Johns Hopkins University | N/A |
| Unknown | Impact of Severe Acute Respiratory Syndrome (SARS-CoV-2/COVID-19) Related Pneumonia on Lung Function and Struc NCT04916834 | National Institute for Tuberculosis and Lung Diseases, Poland | — |
| Completed | Antioxidants as Adjuvant Therapy to Standard Therapy in Patients With COVID-19 NCT04570254 | Unidad Temporal COVID-19 en Centro Citibanamex | N/A |
| Completed | Safety, PK and PD of Kamada Anti-SARS-CoV-2 in COVID-19 NCT04550325 | Kamada, Ltd. | Phase 1 / Phase 2 |
| Completed | Nitric Oxide Therapy for COVID-19 Patients With Oxygen Requirement NCT04476992 | Tomsk National Research Medical Center of the Russian Academy of Sciences | Phase 1 / Phase 2 |
| Completed | TranSfUsion of coNvalescent plAsma for the Early Treatment of pneuMonIa in COVID-19 Patients NCT04716556 | Istituto Superiore di Sanità | N/A |
| Unknown | Obesity Surgery During 2020 Italian Pandemic NCT04480034 | University of Roma La Sapienza | — |
| Withdrawn | Inhaled NO for the Treatment of COVID-19 Caused by SARS-CoV-2 (CANADA Trial) NCT04456088 | Beyond Air Inc. | Phase 2 |
| Terminated | Ultrasonography in Norwegian Emergency Department Patients With Suspected Covid-19 Infection NCT04422691 | St. Olavs Hospital | — |
| Terminated | Glycine Supplement for Severe COVID-19 NCT04443673 | Instituto Nacional de Enfermedades Respiratorias | N/A |
| Terminated | Inhaled NO for the Treatment of COVID-19 Caused by SARS-CoV-2 (US Trial) NCT04397692 | Beyond Air Inc. | N/A |
| Unknown | Low Dose Anti-inflammatory Radiotherapy for the Treatment of Pneumonia by COVID-19 NCT04380818 | Grupo de Investigación Clínica en Oncología Radioterapia | N/A |
| Unknown | High Versus Low LMWH Dosages in Hospitalized Patients With Severe COVID-19 Pneumonia and Coagulopathy NCT04408235 | Azienda Ospedaliero-Universitaria di Modena | Phase 3 |
| Withdrawn | Convalescent Antibodies Infusion in COVID 19 Patients NCT04418531 | Piero Luigi Ruggenenti | N/A |
| Unknown | Inhalation of Ciclesonide for Patients With COVID-19: A Randomised Open Treatment Study (HALT COVID-19) NCT04381364 | Ola Blennow, MD, PhD | Phase 2 |
| Completed | Characterization of Persistent Pulmonary Abnormalities Following COVID-19 Pneumonia NCT04422613 | University Hospital, Toulouse | N/A |
| Completed | Assessment of the Risk of Pulmonary Embolism and Coagulation Profile in Patients With COVID-19 Lung Disease NCT04479540 | Hopital Foch | N/A |
| Unknown | COVID-19 Convalescent Plasma Treatment in SARS-CoV-2 Infected Patients NCT04474340 | Ministry of Health, Kuwait | Phase 1 |
| Completed | HFNC Treatment in COVID-19 Pneumonia NCT04424836 | Sisli Hamidiye Etfal Training and Research Hospital | — |
| Unknown | Natural Killer Cell (CYNK-001) Infusions in Adults With COVID-19 NCT04365101 | Celularity Incorporated | Phase 1 / Phase 2 |
| Completed | Determinants of COVID-19 Pneumonia (MC-19) NCT04387799 | Catholic University of the Sacred Heart | — |
| Completed | Treatment of Covid-19 Associated Pneumonia With Allogenic Pooled Olfactory Mucosa-derived Mesenchymal Stem Cel NCT04382547 | Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | Phase 1 / Phase 2 |
| Terminated | Efficacy and Safety Study of IV Ravulizumab in Patients With COVID-19 Severe Pneumonia NCT04369469 | Alexion Pharmaceuticals, Inc. | Phase 3 |
| Unknown | The Utility of Bedside Lung Ultrasonography on Diagnosis of COVID-19 NCT04399681 | Kanuni Sultan Suleyman Training and Research Hospital | N/A |
| Unknown | COVID-19, bLOod Coagulation and Thrombosis NCT04388657 | Ramsay Générale de Santé | — |
| Unknown | Severe Acute Respiratory Infection - Preparedness (COVID-19 and Influenza) NCT04786301 | University of Washington | — |
| Unknown | International Lung UltraSound Analysis (ILUSA) Study NCT04353141 | KU Leuven | — |
| Unknown | Accuracy of Lung Ultrasound in the Diagnosis of covid19 Pneumonia NCT04370275 | Ospedale di Latisana | — |
| Suspended | Ultra Low Doses of Therapy With Radiation Applicated to COVID-19 NCT04394182 | Fundacion GenesisCare | N/A |
| Completed | Colchicine Counteracting Inflammation in COVID-19 Pneumonia NCT04322565 | Azienda Ospedaliero-Universitaria di Parma | Phase 2 |
| Completed | Nitazoxanide Therapy for Patients With COVID-19 Pneumonia NCT04561219 | Universidade Federal do Rio de Janeiro | Phase 2 |
| Unknown | COVID-19: A Pilot Study of Adaptive Immunity and Anti-PD1 NCT04356508 | Dr Gerry Gin Wai Kwok | Phase 2 |
| Terminated | COVID-19-associated ARDS Treated With Dexamethasone: Alliance Covid-19 Brasil III NCT04327401 | Hospital Sirio-Libanes | Phase 3 |
| Completed | Steroid and Anticoagulant Therapy in covid19 NCT05021588 | Assiut University | N/A |
| Terminated | Hydroxychloroquine Plus Azithromycin Versus Hydroxychloroquine for COVID-19 Pneumonia (COVIDOC Trial) NCT04345861 | University Hospital, Montpellier | Phase 2 / Phase 3 |
| Terminated | Checkpoint Blockade in COVID-19 Pandemic NCT04335305 | MedSIR | Phase 2 |
| Completed | Simple, Safe, Same: Lung Ultrasound for COVID-19 NCT04322487 | Catholic University of the Sacred Heart | — |
| Completed | A Study of the Effectiveness of an Off Label Mefloquine Use for the Treatment of Patients With COVID19 NCT04347031 | Burnasyan Federal Medical Biophysical Center | Phase 2 / Phase 3 |
| Terminated | Chloroquine Phosphate Against Infection by the Novel Coronavirus SARS-CoV-2 (COVID-19): The HOPE Open-Label, N NCT04344951 | Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. | Phase 2 |
| Completed | Enhanced Platelet Inhibition in Critically Ill Patients With COVID-19 NCT04368377 | University of Milan | Phase 2 |
| Completed | French Multicentre Observational Study on SARS-Cov-2 Infections (COVID-19) ICU Management Study NCT04340466 | Centre Hospitalier Universitaire de Nīmes | — |
| Completed | Risk Factors and Computed Tomography Findings in COVID-19. NCT04577105 | Instituto Nacional de Cardiologia Ignacio Chavez | — |
| Completed | Rehabilitation Treatment of Patients With COVID-19 NCT05808361 | I.M. Sechenov First Moscow State Medical University | N/A |
| Completed | Prognostic Factors Keeping Track for COVID-19 Pneumonia NCT04324684 | Catholic University of the Sacred Heart | — |
| Completed | Evolution of Pulmonary Ultrasound in Patients Hospitalized for Covid (Coronavirus Disease) 19 NCT04341766 | Centre Hospitalier Intercommunal Creteil | — |
| Completed | Safety and Efficacy of Hydroxychloroquine Associated With Azithromycin in SARS-CoV2 Virus (Coalition Covid-19 NCT04321278 | Hospital Israelita Albert Einstein | Phase 3 |
| Unknown | Oxygen-Ozone as Adjuvant Treatment in Early Control of COVID-19 Progression and Modulation of the Gut Microbia NCT04366089 | Roberto Poscia MD, PhD | Phase 2 |
| Terminated | Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID-19 NCT04305457 | Massachusetts General Hospital | Phase 2 |
| Completed | Predicting Outcomes for Covid-19 Using Sonography NCT04384055 | Stanford University | — |
| Unknown | Artificial Intelligence Algorithms for Discriminating Between COVID-19 and Influenza Pneumonitis Using Chest X NCT04313946 | Professor Adrian Covic | — |
| Completed | Clinical Characteristics and Outcomes of Pediatric COVID-19 NCT04330261 | University of Calgary | — |
| Completed | Early Short Course Corticosteroids in COVID-19 NCT04374071 | Henry Ford Health System | — |
| Completed | Association Between Body Mass Index and HFNC Therapy Success NCT04799132 | Clínica del country | — |
| Completed | Anti Infective Agents Impact in COVID-19 Pneumonia NCT04453501 | Centre d'Investigation Clinique et Technologique 805 | — |
| Unknown | Predictive Models for Intensive Care Admission and Death of COVID-19 NCT04401228 | Clinique Saint Pierre Ottignies | — |
| Withdrawn | Nitric Oxide Gas Inhalation Therapy for Mild/Moderate COVID19 Infection NCT04290858 | Xijing Hospital | Phase 2 |
| Unknown | Vascular Abnormalities Detected With Chest CT in COVID-19 NCT04824313 | Salah D. Qanadli | — |
| Completed | Toclizumam Versus Dexamethasone in Severe Covid-19 Cases NCT04519385 | South Valley University | N/A |
| Unknown | Characteristics of COVID-19 Patients in Kazakhstan in Early 2020 NCT04627194 | Semey State Medical University | — |
| Terminated | Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia NCT04264533 | ZhiYong Peng | Phase 2 |
| Unknown | Umbilical Cord(UC)-Derived Mesenchymal Stem Cells(MSCs) Treatment for the 2019-novel Coronavirus(nCOV) Pneumon NCT04269525 | ZhiYong Peng | Phase 2 |
| Completed | Pneumonia in the ImmunoCompromised - Use of the Karius Test for the Detection of Undiagnosed Pathogens NCT04047719 | Karius, Inc. | — |
| Unknown | Duration of Antibiotic Therapy in Community - Acquired Pneumonia NCT01492387 | University of Milan | Phase 4 |
| Completed | Long-term Outcome and Lung Capacity in Survivors of ARDS Due to Influenza A (H1N1) v2009 The RESPIFLU Study NCT01271842 | Institut National de la Santé Et de la Recherche Médicale, France | — |
| Unknown | Surveillance of Hospitalised Pneumonia and Bacterial Meningitis in Tône District, Togo, 2010-2013 NCT01747369 | Agence de Médecine Préventive, France | — |
| Terminated | Low Doses Corticosteroids as Adjuvant Therapy for the Treatment of Severe H1N1 Flu NCT01014364 | University of Versailles | Phase 3 |
| No Longer Available | SOLIRIS® (Eculizumab) Treatment of Participants With COVID-19 NCT04355494 | Alexion Pharmaceuticals, Inc. | — |
| No Longer Available | Pulsed Inhaled Nitric Oxide for the Treatment of Patients With Mild or Moderate COVID-19 NCT04358588 | Bellerophon | — |