NCT05279482

Comparison Between Different Doses of Steroids in COVID-19 Patients

Comparison Between Standard Dose Methyl Prednisolone and Megadose Methyl Prednisolone as Regards Outcome in SARS.COV.2 Patients in Intensive Care Unit : Retrospective Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 104 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: —

Summary

aim of this study is to compare between standard dose methyl prednisolone and mega dose methyl prednisolone as regards outcome reflected by mortality rate, percentage of mechanically ventilated patients and icu length of stay of covid 19 patients admitted in intensive care unit.

Detailed description

Retrospective study for comparison between standard dose methyl prednisolone and mega dose methyl prednisolone as regards outcome reflected by mortality rate ,percentage of mechanically ventilated patients and icu length of stay of covid 19 patients admitted in intensive care unit. Previous studies suggested that cytokine release syndrome could be involved in the pathophysiology of critical SARS.COV.2 resulting in death so early suppression of cytokine storm may be lifesaving in critical patients.

Conditions

• Critical Illness
• Pneumonia, Viral

Interventions

Type	Name	Description
OTHER	observation for outcome of methylprednisolone dose	no intervention as it is retrospective study for outcome

Timeline

• Start date: 2022-01-19
• Primary completion: 2022-03-01
• Completion: 2022-03-09
• First posted: 2022-03-15
• Last updated: 2022-03-15

Locations

2 sites across 1 country: Egypt