NCT01492387

Duration of Antibiotic Therapy in Community - Acquired Pneumonia

Individualizing Duration of Antibiotic Therapy in Hospitalized Patients With Community - Acquired Pneumonia: a Non-inferiority, Randomized, Controlled Trial.

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 892 (estimated)
• Sponsor: University of Milan · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to assess the efficacy of an individualized approach to duration of antibiotic therapy based on each subject's clinical response compared to a local standard approach in patients coming from the community and who are hospitalized because of a pneumonia.

Conditions

• Pneumonia
• Bronchopneumonia
• Pleuropneumonia
• Pneumonia, Bacterial
• Pneumonia, Viral

Interventions

Type	Name	Description
OTHER	Discontinuation of antibiotic therapy	Patients randomized in the Individualized Arm will be treated according to clinical response: antibiotic therapy will be discontinued 48 hours after the day that the patient reaches clinical stability, with at least 5 days of total antibiotic treatment.

Timeline

• Start date: 2012-01-01
• Primary completion: 2014-12-01
• Completion: 2015-03-01
• First posted: 2011-12-15
• Last updated: 2014-01-03

Locations

15 sites across 1 country: Italy