| Not Yet Recruiting | Effects of Meal Macronutrients on Postprandial Lipids NCT07313787 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 |
| Active Not Recruiting | SGLT2 Inhibitors in Adult Primary Nephrotic Syndrome NCT07214818 | Mansoura University | Phase 2 / Phase 3 |
| Not Yet Recruiting | Edoxaban Steady-State PK/PD in Adults With Nephrotic Syndrome NCT07116239 | Peking University People's Hospital | N/A |
| Recruiting | Atacicept in Multiple Glomerular Diseases NCT06983028 | Vera Therapeutics, Inc. | Phase 2 |
| Recruiting | Multitarget Strategy for Primary Podocytopathies NCT06718894 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | N/A |
| Active Not Recruiting | The Selection of Initial Treatment Regimens for Adolescent Nephrotic Syndrome. NCT07071597 | Nanjing Children's Hospital | — |
| Active Not Recruiting | Comparing the Performance of Serum Creatinine and Cystatin C-based GFR Estimations in Predicting Directly Meas NCT06797609 | Mario Negri Institute for Pharmacological Research | — |
| Completed | Efficacy And Safety Of Azithromycin To Achieve Remissionin In Children With Steroid Sensitive Nephrotic Syndro NCT07320612 | University of Child Health Sciences and Children's Hospital, Lahore | Phase 1 |
| Recruiting | REduced-dose Steroid PrOtocol for Childhood Nephrotic SyndromE (RESPONSE) NCT06635720 | The Hospital for Sick Children | Phase 3 |
| Recruiting | Cardiac Performance Evaluation in Children With Steroid Dependent vs Steroid Resistant Nephrotic Syndrome NCT06622915 | Sohag University | N/A |
| Not Yet Recruiting | Predictive Determinants of Nephrotic Syndrome Remission in Patients With At-risk Polymorphism of APOL1 NCT06443034 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Effectiveness of Educational Gamified Cards About Nephrotic Syndrome NCT05904197 | Mansoura University | N/A |
| Not Yet Recruiting | Circulating Factors in Nephrotic Syndrome NCT06315504 | Iain Bressendorff | — |
| Recruiting | Autoantibodies Against-nephrin in Idiopathic Nephrotic Syndrome NCT06334692 | Mario Negri Institute for Pharmacological Research | — |
| Recruiting | Steroid Diabetes in Patients With Kidney Disease NCT06161701 | Zhejiang Provincial People's Hospital | — |
| Recruiting | Diuretic Tuner Clinical Decision Support NCT04759274 | University of Texas Southwestern Medical Center | N/A |
| Unknown | Effect of Dapagliflozin in Non-Diabetic Patients With Nephrotic Syndrome. NCT05966818 | Ain Shams University | Phase 4 |
| Recruiting | The Role of Proprotein-convertase-subtilisin/Kexin-type 9 in Kidney Damage in Nephrotic Syndrom NCT06373913 | Kolding Sygehus | — |
| Unknown | Transcriptome Analysis in Idiopathic Nephrotic Syndrome: Steroid Responsiveness NCT06325137 | IRCCS Burlo Garofolo | — |
| Unknown | Efficacy of Anti-CD20 Ab Associated With Anti-CD38 in the Childhood Multidrug Dependent and Resistant Nephroti NCT05704400 | Istituto Giannina Gaslini | Phase 2 |
| Completed | Renal Doppler in Pediatric Patients With Idiopathic Nephrotic Syndrome NCT05912673 | Tanta University | — |
| Recruiting | Ketoanalogues for Muscle Mass Loss in Nephrotic Syndrome NCT05716880 | Military Institute od Medicine National Research Institute | Phase 3 |
| Withdrawn | Part 1 - A Clinical Trial in Patients With Frequently Relapsing and Steroid-Dependent Nephrotic Syndrome NCT05599815 | Aldeyra Therapeutics, Inc. | Phase 2 |
| Recruiting | ARREST-NEPHROSIS - Austrian Resistant Nephrotic Syndrome Treatment Response Registry and Biobank NCT06162546 | Christoph Aufricht | — |
| Unknown | The Predictive Value of Dynamic Changes of CD4+T Lymphocytes in Primary Nephrotic Syndrome With Infection NCT05623033 | Fifth Affiliated Hospital, Sun Yat-Sen University | — |
| Completed | Clinical Value of Adding Dapagliflozin in Patients With Nephrotic Syndrome NCT06026787 | Ain Shams University | Phase 4 |
| Unknown | Characteristics of Peripheral Blood Lymphocyte Subsets in Children With PNS NCT05392244 | Nanfang Hospital, Southern Medical University | — |
| Recruiting | Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome. NCT05505500 | University of Michigan | — |
| Unknown | Effect of Obesity on Cyclosporine Blood Trough Level in Nephrotic Syndrome Patients NCT05696977 | Alexandria University | Phase 4 |
| Unknown | Thrombin Generation Assay to Assess Thrombotic Risk in Nephrotic Patients NCT05301829 | Assistance Publique - Hôpitaux de Paris | — |
| Recruiting | Implementation of a Diagnostic Workflow for Personalized Diagnosis of Nephrotic Syndrome NCT06325098 | Meyer Children's Hospital IRCCS | N/A |
| Completed | A Prospective Multi-dose Study of Apixaban in Subjects With Nephrotic Syndrome NCT04278729 | University of North Carolina, Chapel Hill | Phase 1 |
| Completed | Causes and Prevention of Thromboembolic Disease in Nephrotic Syndrome NCT04850378 | University of Aarhus | Phase 1 / Phase 2 |
| Terminated | Amiloride in Nephrotic Syndrome NCT05079789 | University Hospital Tuebingen | Phase 3 |
| Unknown | From Immune System Damage to Podocyte Cell Damage: Prospective Database and Biological Collection of Patients NCT04174066 | Centre Hospitalier Universitaire de Nice | — |
| Unknown | Non-invasive Assessment of Mechano-chemical Properties of Urine Proteins by Hybrid Brillouin-Raman Spectroscop NCT04311684 | Nazarbayev University | — |
| Recruiting | Belimumab With Rituximab for Primary Membranous Nephropathy NCT03949855 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 2 |
| Recruiting | Clinical Follow-up Study of Rituximab in the Treatment of Nephrotic Syndrome in Children NCT06530004 | The First Affiliated Hospital of Xiamen University | — |
| Unknown | Population Pharmacokinetics of Tacrolimus in Nephrotic Syndrome NCT04045171 | The Third Xiangya Hospital of Central South University | — |
| Completed | B Cells in Idiopathic Nephrotic Syndrome NCT05712369 | Mario Negri Institute for Pharmacological Research | N/A |
| Completed | Role of Montelukast in Preventing Relapse in Childhood Idiopathic Nephrotic Syndrome NCT04818723 | Nishtar Medical University | N/A |
| Unknown | Furosemide Alone or Unexpectedly With Solution of Hypertonic Saline in Nephrotic Syndrome NCT03750136 | Medical University of Bialystok | N/A |
| Completed | Active Vitamin D And Reduced Dose Prednisolone for Treatment in Minimal Change Nephropathy NCT03210688 | University of Aarhus | Phase 4 |
| Completed | Efficacy of a Gluten-free Diet in Difficult to Manage Nephrotic Syndrome: Utility of Plasma Zonulin Levels as NCT03387176 | NYU Langone Health | — |
| Completed | The Efficacy of Huaiqihuang Granule in Children With Primary Nephrotic Syndrome NCT03332420 | Qidong Gaitianli Medicines Co., Ltd | — |
| Completed | Pharmacokinetics of Apixaban in Nephrotic Syndrome NCT02599532 | University of North Carolina, Chapel Hill | Phase 1 |
| Terminated | Effect of PCSK9-Antibody (Alirocumab) on Dyslipidemia Secondary to Nephrotic Syndrome NCT03004001 | Gloria Vega | Phase 2 |
| Unknown | Study of The Association of Mutations in The NPHS2 Gene and Nephrotic Syndrome in Children and Adults in Middl NCT03326037 | AHMED ABDULQADER HAMMOUDA ABOU SHALL | — |
| Unknown | Rituximab Combined With MSCs in the Treatment of PNS (3-4 Stage of CKD) NCT02966717 | Zhujiang Hospital | Phase 2 |
| Recruiting | Super Chinese Nephrotic Syndrome Registration System (SUCCESS) NCT03001934 | Sun Yat-sen University | — |
| Completed | Pilot Study to Evaluate the Safety and Efficacy of Abatacept in Adults and Children 6 Years and Older With Exc NCT02592798 | Bristol-Myers Squibb | Phase 2 |
| Unknown | Diagnostic and Prognostic Value of Miss-1 Study in Children and Adult With Nephrotic Syndrome MISSNEPHROTIQUE NCT03592030 | Assistance Publique - Hôpitaux de Paris | — |
| Terminated | Anti-Xa Activity of Enoxaparin for Prevention of Venous Thromboembolism in Severe Nephrotic Syndrome. NCT04558892 | Military Institute od Medicine National Research Institute | Phase 2 / Phase 3 |
| Unknown | Study of Tacrolimus Used for Pediatric Patients With Nephrotic Syndrome Based on Pharmacogenomics and Metabono NCT02602873 | Guangzhou Women and Children's Medical Center | — |
| Completed | Prednisolone Trial in Children Younger Than 4 Years NCT03141970 | All India Institute of Medical Sciences | Phase 3 |
| Terminated | Ofatumumab in Children With Drug Resistant Idiopathic Nephrotic Syndrome NCT02394106 | Istituto Giannina Gaslini | Phase 2 |
| Completed | Ofatumumab Versus Rituximab in Children With Steroid and Calcineurin Inhibitor Dependent Idiopathic Nephrotic NCT02394119 | Istituto Giannina Gaslini | Phase 2 |
| Completed | Efficacy and Safety of Rituximab to That of Calcineurin Inhibitors in Children With Steroid Dependent Nephroti NCT02438982 | Nilratan Sircar Medical College | Phase 3 |
| Completed | Role of Acetazolamide and Hydrochlorothiazide Followed by Furosemide in Treating Nephrotic Edema NCT02427880 | Shiraz University of Medical Sciences | Phase 4 |
| Unknown | Efficacy and Safety of Rituximab to That of Calcineurin Inhibitors in Children With Steroid Resistant Nephroti NCT02382575 | Nilratan Sircar Medical College | Phase 4 |
| Completed | A Study to Evaluate the Efficacy and Safety of Mizoribine in the Treatment of Refractory Nephrotic Syndrome NCT02257697 | Asahi Kasei Therapeutics Corporation | Phase 3 |
| Completed | Efficacy of Usual Vitamin D Supplementation and Its Impact on Children and Adolescents Calciuria. NCT02238418 | Hospices Civils de Lyon | Phase 4 |
| Completed | Adrenocorticotropic Hormone (ACTH) for Frequently Relapsing and Steroid Dependent Nephrotic Syndrome NCT02132195 | Emory University | Phase 3 |
| Completed | Mycophenolate Mofetil in Pediatric Steroid Dependent Nephrotic Syndrome NCT01895894 | Seoul National University Hospital | Phase 4 |
| Completed | Assessment of the Educational Experiences for Patients Newly Diagnosed With Nephrotic Syndrome NCT02190955 | University of South Florida | — |
| Completed | Lipid Lowering Agents to Limit Lipid Oxidation and Activation of Clotting System in Nephrotic Syndrome NCT01845428 | University of North Carolina, Chapel Hill | Phase 1 |
| Completed | IL-2 for Multi Drug Resistant Nephrotic Syndrome NCT02455908 | Istituto Giannina Gaslini | Phase 1 / Phase 2 |
| Completed | Effectiveness and Safety of Danshen Injection for Acute Kidney Injury in Primary Nephrotic Syndrome NCT06071533 | First Affiliated Hospital of Wenzhou Medical University | — |
| Suspended | Safety and Efficacy of Combination Acthar Gel and Tacrolimus in the Treatment of Steroid Resistant Nephrotic S NCT03042637 | Southeast Renal Research Institute | — |
| Completed | Pharmacokinetics of Tacrolimus in Children NCT03347357 | Shandong University | Phase 4 |
| Completed | Role of PACAP in Nehprotic Syndrome NCT01411982 | Universitaire Ziekenhuizen KU Leuven | — |
| Completed | Pharmacokinetics Following Single-dose of Valsartan in Japanese Pediatric Patients NCT01447485 | Novartis Pharmaceuticals | Phase 1 |
| Completed | Steroid Treatment of Idiopathic Nephrotic Syndrome NCT01386957 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Completed | The Efficacy and Tolerance of Tacrolimus Sustained-release Capsules on Refractory Nephrotic Syndrome (RNS) NCT01309477 | Sun Yat-sen University | Phase 3 |
| Recruiting | INSIGHT (Insight Into Nephrotic Syndrome) NCT01605266 | The Hospital for Sick Children | — |
| Recruiting | Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy NCT00977977 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 |
| Completed | Registry for Patients With Wilms' Tumor Suppressor Gene 1 (WT1) Mutation Associated Diseases NCT01252901 | Universitätsklinikum Hamburg-Eppendorf | — |
| Completed | Therapeutic Effect of Tacrolimus on Primary Nephrotic Syndrome in Children NCT01162005 | Seoul National University Hospital | Phase 4 |
| Completed | Evaluation of Low Dose Corticosteroids Efficiency, Associated With Myfortic ® in the Treatment of Nephrotic Sy NCT01197040 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | Adrenocorticotropic Hormone (ACTH) Treatment of Nephrotic Range Proteinuria in Diabetic Nephropathy (NRDN) NCT01028287 | Southeast Renal Research Institute | Phase 4 |
| Completed | Rituximab in Multirelapsing Minimal Change Disease (MCD) or Focal Segmental Glomerulosclerosis (FSGS) NCT00981838 | Mario Negri Institute for Pharmacological Research | Phase 3 |
| Terminated | Cardiomyopathy in Steroid-resistant Nephrotic Syndrome: Impact of Focal Segmental Glomerulosclerosis NCT00883636 | Northwell Health | — |
| Unknown | Lymphocyte Markers As Predictors Of Responsiveness To Rituximab Among Patients With Idiopathic Nephrotic Syndr NCT03501459 | National University Health System, Singapore | Phase 3 |
| Completed | Fluid Balance, Hormones and Urine Proteomics in Nephrotic Syndrome in Childhood NCT00690586 | Aarhus University Hospital | — |
| Completed | Pharmacokinetics of Cyclosporin in Nephrotic Syndrome NCT01616446 | University of Sao Paulo | — |
| Completed | Efficacy of Pentoxifylline on Primary Nephrotic Syndrome NCT00354731 | National Taiwan University Hospital | Phase 3 |
| Completed | Prospective, Multicenter Study of the Efficacy and Tolerance of Tacrolimus on Refractory Nephrotic Syndrome (R NCT00615667 | Sun Yat-sen University | Phase 3 |
| Completed | The Effects of Helicobacter Pylori Eradication on Proteinuria in Patients With Membranous Nephropathy NCT00983034 | Istanbul University | N/A |
| Completed | Urinary Aquaporin 2 and Expression of the NPHS2 Gene in Adults Suffering From Nephrotic Syndrome NCT00286910 | Regional Hospital Holstebro | — |
| Completed | Steroid-Induced Osteoporosis in the Pediatric Population - Canadian Incidence Study NCT01663129 | Children's Hospital of Eastern Ontario | — |
| Completed | Tacrolimus Combined With Prednisone Treatment of Idiopathic Membranous Nephropathy and Nephrotic Syndrome NCT00362531 | Peking University | Phase 2 / Phase 3 |
| Unknown | Long Term Tapering or Standard Steroids for Nephrotic Syndrome NCT00308321 | Institute of Child Health | Phase 4 |
| Completed | Glucocorticoid-induced Osteopenia in Children NCT00289328 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |
| Completed | Study of the Safety and Efficacy of NC-503 in Secondary (AA) Amyloidosis NCT00035334 | Bellus Health Inc. - a GSK company | Phase 2 / Phase 3 |
| Completed | Once-A-Month Steroid Treatment for Patients With Focal Segmental Glomerulosclerosis NCT00004990 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 |
| Completed | Pirfenidone to Treat Kidney Disease (Focal Segmental Glomerulosclerosis) NCT00001959 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 |
| Terminated | Pilot Study of Atorvastatin in Children With Chronic Hyperlipidemia Secondary to Nephrotic Syndrome NCT00004466 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 |
| Active Not Recruiting | Genetic Causes of FSGS, Nephrotic Syndrome, or Kidney Failure NCT02194582 | Beth Israel Deaconess Medical Center | — |
| Recruiting | Immune System Related Kidney Disease NCT00001979 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |
| Completed | Drug Therapy in Lupus Nephropathy NCT00001212 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 |
| Completed | Angiotensin Converting Enzyme Gene Polymorphism in Children With Idiopathic Nephrotic Syndrome NCT00172276 | National Taiwan University Hospital | — |