NCT00308321

Long Term Tapering or Standard Steroids for Nephrotic Syndrome

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Institute of Child Health · Academic / Other
• Sex: All
• Age: 1 Year – 15 Years
• Healthy volunteers: Not accepted

Summary

Parallel group double blind randomised in patients with first episode corticosteroid sensitive nephrotic syndrome comparing time to relapse and adverse effects associated with a longer tapering steroid regimen with standard regime

Conditions

• Nephrotic Syndrome

Interventions

Type	Name	Description
DRUG	long term tapering of prednisolone	60mg/m2/day (0-4 weeks); 60mg/m2 alternate days (5-6 weeks); 50mg/m2 alternate days (week 7-8); 40mg/m2 alternate days (week 9-10); 30mg/m2 alternate days (week 11-12); 20mg/m2 alternate days (week 13-14); 10mg/m2 alternate days (week 15-16)
DRUG	standard prednisolone treatment	60mg/m2/day week 0-4; 40mg/m2 on alternate days week 5-8

Timeline

• Start date: 2003-09-01
• Completion: 2008-10-01
• First posted: 2006-03-29
• Last updated: 2007-11-29

Locations

1 site across 1 country: United Kingdom