NCT07320612

Efficacy And Safety Of Azithromycin To Achieve Remissionin In Children With Steroid Sensitive Nephrotic Syndrome

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 160 (actual)
• Sponsor: University of Child Health Sciences and Children's Hospital, Lahore · Academic / Other
• Sex: All
• Age: 2 Years – 14 Years
• Healthy volunteers: Accepted

Summary

To compare efficacy and safety of Azithromycin versus control in children with steroid sensitive nephrotic syndrome

Detailed description

It is a randomized controlled trial. Total 160 children meeting inclusion criteria will be included in the study. Selected children will be divided into 2 groups. one group will be given Azithromycin at 10mg/kg/day (1 dose per day) for 3 days along with standard course of steroids. 2nd group will be given standard course of treatment. All patients will be followed up for 1 month and remission will be noted. All data will be collected through specially designed performa. Patient's safety and Efficacy of drug in Achieving early Remission will be closely monitored.

Conditions

• Nephrotic Syndrome

Interventions

Type	Name	Description
DRUG	Azithromycin and steroids	80 children will be assigned group A and children will be given Azithromycin along with standard course of steroids.
DRUG	steroids	80 children will be assigned group B and will be given only standard course of treatment

Timeline

• Start date: 2025-03-08
• Primary completion: 2025-08-08
• Completion: 2025-10-08
• First posted: 2026-01-06
• Last updated: 2026-01-06

Locations

1 site across 1 country: Pakistan