NCT05912673

Renal Doppler in Pediatric Patients With Idiopathic Nephrotic Syndrome

Renal Doppler in Detection of Steroid Resistance in Pediatric Patients With Idiopathic Nephrotic Syndrome

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 60 (actual)
• Sponsor: Tanta University · Academic / Other
• Sex: All
• Age: 1 Year – 18 Years
• Healthy volunteers: Not accepted

Summary

The use of the renal resistive index in pediatric patient with idiopathic nephrotic syndrome to detect steroid resistance and to use it as a prognostic instrument of the progression of the disease.

Detailed description

Renal Doppler will be done for all children in supine and lateral positions using Toshiba Aplio ultrasound machine and renal resistive index will be measured (peak systolic velocity- end diastolic velocity/ peak systolic velocity) at diagnosis, after one month, 3 months and 6months, in which these values will be obtained by the ultrasound machine based on the computer algorithm. Also the kidneys will be scanned firstly for length, width, cortical thickness and echogenicity.

Conditions

• Nephrotic Syndrome

Interventions

Type	Name	Description
DEVICE	renal doppler	Toshiba Aplio ultrasound machine and renal resistive index will be measured (peak systolic velocity- end diastolic velocity/ peak systolic velocity

Timeline

• Start date: 2023-01-28
• Primary completion: 2023-07-30
• Completion: 2023-08-30
• First posted: 2023-06-22
• Last updated: 2024-01-24

Locations

1 site across 1 country: Egypt

Regulatory

• FDA-regulated device study