NCT02194582

Genetic Causes of FSGS, Nephrotic Syndrome, or Kidney Failure

Molecular and Genetic Analysis of Inherited Kidney Dysfunction

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 2,050 (estimated)
• Sponsor: Beth Israel Deaconess Medical Center · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

The investigators are trying to learn more about the cause of kidney diseases such as Focal Segmental Glomerulosclerosis (FSGS) and Nephrotic syndrome by studying genetics. The investigators are interested in discovering which genes play a role in causing a predisposition to FSGS/NS. The investigators also want to learn why FSGS/NS can run in families. Participation in our study involves a saliva sample and a urine sample that you can give from home. There is no cost to participate. All information is kept private and confidential. The investigators also like to include healthy volunteers (parents, spouses) if interested/available but of course this is completely optional.

Detailed description

The investigators welcome anyone (with or without a family history) with unexplained, non syndromic FSGS, nephrotic syndrome, or proteinuria to join the study. Participation involves a saliva (or blood if it is preferable) sample and urine sample (if applicable). There is no cost to participate and the study can be done from home in most cases.

Conditions

• Focal Segmental Glomerulosclerosis
• Nephrotic Syndrome
• End Stage Renal Disease
• Kidney Failure
• Unexplained Proteinuria

Timeline

• Start date: 1996-06-01
• Primary completion: 2035-01-01
• Completion: 2035-01-01
• First posted: 2014-07-18
• Last updated: 2024-11-05

Locations

1 site across 1 country: United States