| Not Yet Recruiting | FANS vs CVAC for Medium to Large Stones NCT07514351 | Ohio State University | N/A |
| Not Yet Recruiting | DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones NCT07516535 | Ain Shams University | N/A |
| Not Yet Recruiting | Effect of Complete Suction-Induced Collapse of the Renal Collecting System at the End of RIRS on Early Postope NCT07535281 | Kangdong Sacred Heart Hospital | N/A |
| Not Yet Recruiting | Erector Spinae Plane Block for Percutaneous Nephrolithotomy NCT07457983 | Fadime Tosun | N/A |
| Not Yet Recruiting | Metaphylaxis of Infected Kidney Stones After Percutaneous Nephrolithotripsy NCT07393711 | West Kazakhstan Marat Ospanov Medical University | N/A |
| Not Yet Recruiting | Effect of Comprehensive Spa Care on Kidney and Urological Conditions: A Clinical Study in Adult Patients NCT07435844 | Institute of Spa and Balneology, public research institution | N/A |
| Not Yet Recruiting | Sodium Bicarbonate as an Alternative to Potassium Citrate for Kidney Stones NCT07408076 | University of California, Los Angeles | Phase 1 / Phase 2 |
| Recruiting | Comparison Between Different Types of Flexible Ureteroscopes NCT07360353 | Ain Shams University | N/A |
| Recruiting | Early vs Delayed Extracorporeal Shock Wave Lithotripsy for Residual Stones After Percutaneous Nephrolithotomy NCT07523074 | Beni-Suef University | N/A |
| Not Yet Recruiting | Postoperative Analgesia Practices After Percutaneous Nephrolithotomy NCT07258901 | Istinye University | — |
| Not Yet Recruiting | Is CYP24A1 Heterozygosity a Risk Factor for Nephrolithiasis? NCT07201701 | Hospices Civils de Lyon | — |
| Not Yet Recruiting | Comparing Efficiency and Stone-Free Rates Mini PCNL vs Flex URS NCT07072598 | Northwestern University | N/A |
| Completed | Inflammatory Response Under Spinal vs General Anesthesia in PCNL: NLR, RDW, LAR. NCT07205224 | Sevim Şenol Karataş | — |
| Recruiting | Comparison of Extracorporeal Shock Wave Lithotripsy Versus Retrograde Intrarenal Surgery in the Management of NCT07261995 | Ziauddin Hospital | N/A |
| Not Yet Recruiting | HoYAG vs TFL in miniPCNL With ClearPetra NCT07087977 | University of Kansas Medical Center | N/A |
| Recruiting | ClearPetra™ Vacuum-assisted Ureteral Access Sheath vs Traditional Approach NCT06547632 | University of Kansas Medical Center | N/A |
| Recruiting | Hemodynamic Effects of Surgical Position in Prone vs. Supine Percutaneous Nephrolithotomy NCT07138872 | Gaziosmanpasa Research and Education Hospital | N/A |
| Not Yet Recruiting | Comparison of Myocardial Injury After Noncardiac Surgery (MINS) Incidence in Supine vs. Prone Positioning Duri NCT06944301 | Medipol University | N/A |
| Completed | Safety and Efficacy of Traditional Versus Flexible and Navigable Suction Sheath in Retrograde Intra-Renal Ston NCT07286071 | Ain Shams University | N/A |
| Recruiting | Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone Disease NCT06989320 | University of Alabama at Birmingham | N/A |
| Not Yet Recruiting | Trial to Assess the Efficacy of EMPAgliflozin and Personalized Dietary Counseling for Kidney STONE Prevention NCT06653738 | Insel Gruppe AG, University Hospital Bern | Phase 3 |
| Recruiting | RIRS With Flex Suction Sheath vs. PCNL for 2-3 cm Renal Stones NCT07058402 | Changhai Hospital | N/A |
| Not Yet Recruiting | Comparison of Flexible & Navigable Suction Ureteral Access Sheath vs. Antegrade Suction in Retrograde Flexible NCT06889051 | Benha University | N/A |
| Recruiting | Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain NCT06635889 | University of Chicago | Phase 2 |
| Recruiting | Evaluation of Genetic Abnormalities Amongst Calcium Phosphate Stone Formers NCT06974357 | Ryan L Steinberg | N/A |
| Completed | ESP Block for Postoperative Analgesia in URS Surgery NCT06826833 | Namik Kemal University | N/A |
| Recruiting | Evaluation of the LithoVue Elite Ureteroscope With Intra-Renal Pressure Monitoring Technology: Examination of NCT06576661 | University of Kansas Medical Center | N/A |
| Completed | Comparison Between Supine Mini-PCNL and Flexible Ureteroscopy (FURS) for Dense Lower Calyceal Stones (1-2 cm) NCT07345234 | Ain Shams University | N/A |
| Completed | Sheathless, Traditional, and Suction Access Sheath RIRS for Renal Stones ≤2 cm NCT07289230 | Ain Shams University | N/A |
| Recruiting | Bendable Suction Ureteral Access Sheath Versus Conventional Ureteral Access Sheath in Management of Renal Ston NCT06862141 | Menoufia University | N/A |
| Completed | Tubeless vs Tube PCNL in Pediatric Nephrolithiasis: A Randomized Controlled Trial. NCT07183930 | Lady Reading Hospital, Pakistan | N/A |
| Completed | Intraocular Pressure, Optic Nerve Sheath Diameter and Optic Perfusion Pressure of Minimal Low and High-Flow An NCT06684704 | Elazıg Fethi Sekin Sehir Hastanesi | N/A |
| Not Yet Recruiting | The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants. NCT06199102 | Princess Anna Mazowiecka Hospital, Warsaw, Poland | N/A |
| Recruiting | Thulium Fiber Laser (TFL) vs Thulio Pulsed Thulium:YAG (p-Tm:YAG) NCT06721975 | University of California, San Diego | N/A |
| Recruiting | Comparison Between Ureterorenoscopy With Lithotripsy Alone Versus Combination With Hydrogel for Kidney Stone R NCT06469736 | Technical University of Munich | N/A |
| Recruiting | O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease NCT06330246 | University of Alabama at Birmingham | N/A |
| Recruiting | Gut Oxalate Absorption in Calcium Oxalate Stone Disease NCT06331546 | University of Alabama at Birmingham | N/A |
| Recruiting | Exploratory Study on the Treatment of Gout With Potassium Citrate Sustained-release Tablets NCT06966635 | Huashan Hospital | Phase 4 |
| Enrolling By Invitation | Comparison of Holmium Laser and Thulium Laser for Mini PCNL NCT06266793 | MaineHealth | N/A |
| Active Not Recruiting | Use of POCUS and STONE Criteria Together in the Diagnosis of Nephrolithiasis NCT07126847 | Kocaeli City Hospital | — |
| Terminated | Massage Percussion for Passage of Urolithiasis Fragments After Ureteroscopy. NCT05872230 | Vanderbilt University Medical Center | N/A |
| Completed | Dual-process Mechanisms of Action for sipIT Intervention Effects in Patients With Urolithiasis NCT06269783 | University of Michigan | N/A |
| Unknown | Preoperative Prophylactic Antibiotic Duration in Moderate to High Risk Ureteroscopy NCT06149455 | University of California, San Francisco | N/A |
| Recruiting | Alpha-Blockers Prior to Ureteral Access Sheath Placement in Flexible Ureteroscopy: A Randomized Prospective St NCT07124299 | Pedro de Figueiredo Buchalla | Phase 4 |
| Completed | Flexible and Navigable Suction Ureteral Access Sheath (FANS) vs Conventional Access Sheaths in RIRS: A Prospec NCT07377461 | Barzilai Medical Center | N/A |
| Recruiting | Serum Endotoxin Assay to Predict the Development of Postoperative Infectious Complications and Systemic Inflam NCT04669886 | University of Miami | — |
| Active Not Recruiting | SOUND Pivotal Trial - (Sonomotion stOne comminUtion resoNance ultrasounD) NCT05701098 | SonoMotion | N/A |
| Completed | Evaluation of Stone Composition in Surgical Kidney Stone Patients in Vietnam NCT07038954 | Binh Dan Hospital | — |
| Completed | Narcotic-Free Percutaneous Nephrolithotomy NCT05924165 | Icahn School of Medicine at Mount Sinai | Phase 4 |
| Completed | The Application of Health Education Path Nursing Program NCT07047625 | Fuyang Affiliated Hospital of Anhui Medical University | N/A |
| Completed | Empiric Versus Selective Prevention Strategies for Kidney Stone Disease NCT05365477 | Vanderbilt University Medical Center | Phase 4 |
| Completed | Evaluating the Vitamin K2 Status of Calcium-based Stone Formers NCT05081960 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Completed | Retrograde Intrarenal Surgery (RIRS) With High-Power Laser and Flexible, Navigable Suction Access Sheath (FANS NCT07349992 | Necmettin Erbakan University | N/A |
| Completed | Comparison of Erector Spinae Plane Block and Intravenous Patient-controlled Analgesia in Percutaneous Nephroli NCT05845281 | Yuzuncu Yil University | N/A |
| Completed | Thulium vs. Hol:YAG Laser NCT05808257 | Icahn School of Medicine at Mount Sinai | N/A |
| Completed | Trial Assessing Renal Damage During Ureteroscopy NCT05350423 | Icahn School of Medicine at Mount Sinai | N/A |
| Recruiting | Methocarbamol vs Oxybutynin for Management of Pain and Discomfort S/P Ureteroscopy Procedure NCT05100017 | Northwestern University | N/A |
| Recruiting | Kidney Sodium Functional Imaging NCT05014178 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Enrolling By Invitation | PRedictive Accuracy of Initial Stone Burden Evaluation. NCT04746378 | University Hospital, Ghent | — |
| Completed | Paravertebral Block Versus Erector Spinae Plain Block In Percutaneous Nephrolithotomy NCT04998435 | Nazmy Edward Seif | N/A |
| Completed | Effect of Antihistamines on Ureteral Stent-Related Symptoms NCT04726345 | Columbia University | Phase 2 |
| Completed | DS Titanium Ligation Clip in Urology (Prostatectomy and Nephrectomy) NCT04869462 | Aesculap AG | — |
| Recruiting | Prediction of Recurrence and Complications of Nephrolithiasis Using a Precision Medicine Approach NCT05237063 | Centre Hospitalier Universitaire, Amiens | N/A |
| Completed | A Comparison of Ureteroscopic Treatment of Nephrolithiasis With and Without Moses Technology NCT04505956 | Vanderbilt University Medical Center | N/A |
| Completed | Multicenter, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Fluconazole in Hype NCT04495608 | Hospices Civils de Lyon | Phase 2 |
| Completed | Noninvasive Electrical Stimulator as a Pain Control Treatment Post-ureteroscopy NCT05153629 | Stanford University | N/A |
| Completed | Evaluation of a Nonopioid Recovery Pathway Following Surgery for Kidney Stones NCT04597619 | The Miriam Hospital | N/A |
| Completed | Mini-PNCL vs fURS in Management of Nephrolithiasis NCT04389853 | Thunder Bay Regional Health Research Institute | N/A |
| Unknown | Effect of Furosemide on ESWL Outcomes for Renal and Ureteral Calculi NCT05270421 | Shiraz University of Medical Sciences | Phase 3 |
| Completed | Intraoperative Cone-beam CT for Percutaneous Nephrolithotomy NCT04556396 | Loyola University | N/A |
| Completed | Study of the Administration of a Food Supplement in Patients With Lithiasis Treated With Extracorporeal Shock NCT05525130 | Arafarma Group, S.A. | N/A |
| Completed | Pediatric KIDney Stone (PKIDS) Care Improvement Network NCT04285658 | Children's Hospital of Philadelphia | — |
| Unknown | Comparison of SP TFL and Ho:YAG for RIRS Using 145 µm and 200 µm Fibers NCT04346485 | I.M. Sechenov First Moscow State Medical University | N/A |
| Unknown | Mirabegron And Ureteral Stent-related Pain (MAP) Trial NCT04286152 | Unity Health Toronto | Phase 3 |
| Unknown | Patient Compliance for Metabolic Evaluation and Medical Management in Calcium Stone Patients NCT04169165 | EULIS Colloborative Research Working Group | — |
| Unknown | Efficacy of Ciprofloxacin Therapy in Avoidance of Sepsis in Patient Undergoing Percutanous Nephrolithotomy NCT04374188 | Diaa Eldin Taha Ramadan Mohamed | N/A |
| Unknown | Efficacy of Tranexamic Acid on Blood Loss During Percutaneous Nephrolithotomy. NCT04367155 | Kafrelsheikh University | N/A |
| Unknown | Mini- Percutaneous Nephrolithotomy Versus Standard Percutaneous Nephrolithotomy in the Treatment of Renal Ston NCT04153461 | Mansoura University | N/A |
| Completed | Perioperative Pregabalin in Ureteroscopy: a Pilot NCT03927781 | University of Missouri-Columbia | Phase 3 |
| Completed | Ultrasound First Clinical Decision Support for Suspected Nephrolithiasis NCT03461536 | University of California, San Francisco | N/A |
| Terminated | Validation of Low Dose CT for Diagnosis of Urolithiasis NCT03656913 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | Effect of Hydroxycitrate on Urine Chemistry NCT03348228 | NYU Langone Health | N/A |
| Completed | Antibiotic Prophylaxis Before Shock Wave Lithotripsy NCT03692715 | Clinical Urology and Epidemiology Working Group | Phase 4 |
| Completed | Pain Outcomes of Non-opioid vs. Opioid Analgesia for Kidney Stone Surgery. NCT03584373 | Montefiore Medical Center | Phase 3 |
| Unknown | Comparison of the Impact of Diet vs Thiazide in BMD in Children With Idiopathic Hypercalciuria NCT03951558 | Hospital Infantil de Mexico Federico Gomez | N/A |
| Withdrawn | Evaluation of Two Different Treatments for Lower Pore Renal Stone: Microperc Vs FURS NCT03307096 | Ningbo No. 1 Hospital | N/A |
| Unknown | Lanthanum Carbonate (Fosrenol®) to Reduce Oxalate Excretion in Patients With Secondary Hyperoxaluria and Nephr NCT03346369 | Universitair Ziekenhuis Brussel | Phase 3 |
| Withdrawn | Contrast-enhanced Ultrasound Versus CT Scan for Kidney Stone Patient Management NCT03058614 | University of California, San Francisco | Phase 2 |
| Completed | Trial of Tadalafil, Tamsulosin and Combination for Access Sheath Deployment NCT03229889 | University of California, Irvine | Phase 4 |
| Unknown | The Association Between Nephrolithiasis and Periodontal Status NCT03102086 | Rambam Health Care Campus | — |
| Completed | Monitored vs Standard Supplementation of Vitamin D in Preterm Infants NCT03087149 | Princess Anna Mazowiecka Hospital, Warsaw, Poland | N/A |
| Completed | Strategies to Maximise Patient Comfort During ESWL NCT03379922 | Cliodhna Browne | N/A |
| Unknown | Mature Vinegar Prophylaxis Against Recurrent Calcium Oxalate Nephrolithiasis NCT03092908 | The First Affiliated Hospital of Guangzhou Medical University | N/A |
| Completed | Hydrochlorothiazide for Kidney Stone Recurrence Prevention NCT03057431 | Insel Gruppe AG, University Hospital Bern | Phase 3 |
| Completed | Alkalinization by Urologists & Nephrologists NCT03035812 | Jean-Philippe Bertocchio | Phase 4 |
| Completed | Hidrate Me Smart Water Bottle Use in Patient With Nephrolithiasis NCT02938884 | University of Minnesota | N/A |
| Unknown | Over 2000 Epidural Anesthesias for Percutaneous Nephrolithotomy - a Retrospective Analysis NCT02986997 | Medical University of Warsaw | — |
| Completed | A Pilot Study of Oxalate Absorption in Secondary Hyperoxaluria NCT03095885 | Allena Pharmaceuticals | N/A |
| Completed | Conditional Imaging Prescription Strategy for Exploration of Acute Uncomplicated Renal Colic NCT02878148 | University Hospital, Montpellier | N/A |
| Terminated | Understanding the Urine Electrolyte Profile of the Individual Renal Unit NCT02837393 | Johns Hopkins University | — |
| Unknown | Impact of Tranexamic Acid Use in Percutaneous Nephrolithotomy NCT02966236 | University of Sao Paulo | Phase 4 |
| Completed | Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PC NCT02829060 | University of California, San Diego | N/A |
| Completed | Subcostal TAP Block For Percutaneous Nephrolithotomy NCT03454139 | Istanbul University | N/A |
| Completed | Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Secondary Hyperoxaluria and Kidne NCT02547805 | Allena Pharmaceuticals | Phase 2 |
| Completed | Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Hyperoxaluria and Kidney Stones NCT02503345 | Allena Pharmaceuticals | Phase 2 |
| Completed | Kidney Stone Risk Factors in Patients Infected With HIV NCT02457494 | Corinne Isnard Bagnis | — |
| Completed | A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephro NCT02384200 | University of California, San Diego | Phase 4 |
| Unknown | Comparison of Safety and Efficiency of 20w and 30w Holmium Laser Device in Management of 2-3 cm Diameter Kidne NCT02443909 | Diskapi Teaching and Research Hospital | Phase 4 |
| Active Not Recruiting | Ultrasound Imaging of Kidney Stones and Lithotripsy NCT02214836 | University of Washington | N/A |
| Unknown | Comparison of Safety and Efficiency of 20w 30w Holmium Laser Device in Treatment of 1-2 cm Diameter Kidney Sto NCT02451319 | Diskapi Teaching and Research Hospital | Phase 4 |
| Unknown | Is There Any Relation Between Pain and Stone Location in Retrograde Intrarenal Surgery? NCT02430883 | Diskapi Teaching and Research Hospital | Phase 4 |
| Unknown | Prospective Comparison Between Different Laser Settings for Ureteral \ Kidney Stones Treatment During Ureteros NCT02279927 | Carmel Medical Center | N/A |
| Completed | Evaluating ALLN-177 for Reducing Urinary Oxalate Excretion in Calcium Oxalate Kidney Stone Formers With Hypero NCT02289755 | Allena Pharmaceuticals | Phase 2 |
| Completed | Validation of the Wisconsin Stone-QOL NCT02188108 | University of Wisconsin, Madison | N/A |
| Completed | Impact Ureteral Sheath Design During Ureteroscopy NCT03349099 | The Cleveland Clinic | N/A |
| Unknown | Safety and Effectiveness of the Ultrasonic Propulsion of Kidney Stones NCT02028559 | University of Washington | N/A |
| Completed | Ureteral Stent-related Pain and Mirabegron (SPAM) Trial NCT02095665 | Nova Scotia Health Authority | Phase 4 |
| Completed | Diagnostic Relevance of Laser Confocal Microscopy for the Screening of Upper Urinary Tract Tumors NCT02276924 | Lille Catholic University | N/A |
| Completed | The Use of Belladonna and Opium Suppository in the Treatment of Postoperative Stent Pain NCT03332056 | University of Washington | Phase 4 |
| Completed | "Dusting" Versus "Basketing" - Treatment Of Intrarenal Stones NCT01619735 | Mayo Clinic | — |
| Completed | Influence of Polymorphisms in the ATP6V1 Gene of the V-ATPase on the Development of Incomplete Distal Renal Tu NCT01690039 | Insel Gruppe AG, University Hospital Bern | — |
| Completed | Comparison of DASH With Oxalate Restricted Diet on Urine in Recurrent Stone Formers With Hyperoxaluria NCT01650935 | Shahid Beheshti University of Medical Sciences | N/A |
| Terminated | Trial Comparing the Effect of a Paravertebral Block on Pain Post Percutaneous Nephrolithotomy NCT01371422 | University of British Columbia | N/A |
| Completed | Vitamin D Repletion in Stone Formers With Hypercalciuria NCT01295879 | New York Presbyterian Hospital | Phase 4 |
| Terminated | Efficacy and Safety of Using MPC-5971 in Subjects Undergoing Shock Wave Lithotripsy NCT00860093 | Mission Pharmacal | Phase 2 |
| Completed | Effect of Diet Orange Soda on Urinary Lithogenicity NCT01330940 | VA New York Harbor Healthcare System | N/A |
| Withdrawn | The Effect of Vitamin D on Urinary Calcium Excretion in Kidney Stone Formers With High Urinary Calcium NCT00948740 | Brigham and Women's Hospital | Phase 2 / Phase 3 |
| Completed | Nephrolithiasis Prevention by Lemon Juice NCT01217372 | Mario Negri Institute for Pharmacological Research | Phase 2 |
| Unknown | Does Treatment With Alfuzosin Increase Success Rates of (SWL) Shock Wave Lithotripsy NCT00409227 | Assaf-Harofeh Medical Center | Phase 2 |
| Completed | The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients NCT00600405 | MaineHealth | N/A |
| Completed | Use of Oral Probiotics to Reduce Urinary Oxalate Excretion NCT00587041 | Mayo Clinic | Phase 1 / Phase 2 |
| Completed | Nephrolithiasis and Bariatric Surgery NCT00169793 | Indiana Kidney Stone Institute | N/A |
| Terminated | Genetic Study of Nephrolithiasis in Gouty Diathesis NCT00149305 | Mario Negri Institute for Pharmacological Research | — |
| Completed | Blood Parameters as a Predictor of Fever After Percutaneous Nephrolithotomy NCT03774940 | TC Erciyes University | N/A |
| Completed | Postoperative Telerounding: A Multi-Center Prospective Randomized Assessment of Patient Outcomes and Satisfact NCT00263107 | University of California, Davis | — |
| Completed | Percutaneous Nephrolithotomy: A Registry and Database NCT00159393 | Indiana Kidney Stone Institute | — |
| Completed | Brushite Kidney Stones: A Registry and Database of Clinical and Laboratory Findings NCT00169663 | Indiana Kidney Stone Institute | — |
| Terminated | Dose-Dependent Effect of Thiazide in Dent's Disease Hypercalciuria NCT00638482 | Assistance Publique - Hôpitaux de Paris | Phase 2 / Phase 3 |
| Completed | Oral Antibiotic Treatment of Helicobacter Pylori Reduces Intestinal Colonization Rates With Oxalobacter Formig NCT01300039 | VA New York Harbor Healthcare System | — |
| Completed | Kidney Stone Structural Analysis By Helical Computed Tomography (CT) NCT00169780 | Indiana Kidney Stone Institute | — |
| Completed | The Success of Pediatric Percutaneous Nephrolithotomy NCT04299204 | Osmaniye Government Hospital | N/A |
| Completed | Genetic Determinants of Opioids Analgesia NCT00226564 | Hadassah Medical Organization | N/A |