NCT00600405

The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 81 (actual)
• Sponsor: MaineHealth · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine the efficacy of the α-adrenergic antagonist tamsulosin in the treatment of adult emergency department (ED) patients with ureteral colic secondary to lower ureteral calculus. We hypothesize that there will be no difference in outcomes for subjects treated with and without tamsulosin.

Detailed description

This prospective, randomized controlled trial seeks to compare outcomes for adult emergency department patients with lower ureteral calculus. Subjects will be randomized to receive treatment with ibuprofen and oxycodone alone (standard therapy) or standard therapy plus tamsulosin 0.4mg orally once daily for ten days.

Conditions

• Nephrolithiasis
• Ureteral Calculi

Interventions

Type	Name	Description
DRUG	tamsulosin	Tamsulosin 0.4 mg orally daily for ten days.
DRUG	Standard therapy with ibuprofen and oxycodone.	Oxycodone: 5mg, one to two tablets every four to six hours as needed for pain. Ibuprofen: 800 mg, one three times a day with food as needed for pain.

Timeline

• Start date: 2006-08-01
• Primary completion: 2007-11-01
• Completion: 2007-11-01
• First posted: 2008-01-25
• Last updated: 2008-01-25

Locations

1 site across 1 country: United States