NCT03348228

Effect of Hydroxycitrate on Urine Chemistry

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: NYU Langone Health · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Hydroxycitrate (HCA) is a compound extracted from the fruit, Garcinia Cambogia. Hydroxycitrate supplements are available over the counter and are primarily promoted as a weight loss supplement. There has been recent evidence that hydroxycitrate is a potent inhibitor of calcium oxalate crystal growth and can lead to the dissolution of the crystals. The purpose of this research study is to study the effect of Hydroxycitrate (HCA) supplements on HCA urinary excretion and on urine chemistries in kidney stone formers and normal subjects.

Conditions

• Nephrolithiasis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Hydroxycitrate (HCA)	Hydroxycitrate supplements are available over the counter and are primarily promoted as a weight loss supplement. Each subject will be given 42 capsules of Swanson super citrimax (hydroxycitrate) Details of the product are provided above. The subjects will be asked to take the capsules over a seven period (6 capsules per day).

Timeline

• Start date: 2018-10-04
• Primary completion: 2020-12-15
• Completion: 2020-12-15
• First posted: 2017-11-20
• Last updated: 2022-01-26

Locations

1 site across 1 country: United States