Trials / Conditions / Mitral Valve Regurgitation

Mitral Valve Regurgitation

70 registered clinical trials studyying Mitral Valve Regurgitation — 11 currently recruiting.

Status	Trial	Sponsor	Phase
Withdrawn	Understanding the Metabolic and Functional Derangement of Primary Mitral Regurgitation: a Feasibility Study Us NCT04795856	University of Alabama at Birmingham	EARLY_Phase 1
Not Yet Recruiting	The Asia-Pacific Mitral & Tricuspid Valve-in-Valve/Valve-in-Ring Registry NCT07296016	Prince of Wales Hospital, Shatin, Hong Kong	—
Recruiting	Impact of Transcatheter Aortic Valve Implantation and Mitral Valve Repair on Sleep-Disordered Breathing NCT07520656	Aristides Plaitis	—
Recruiting	AltaValve Pivotal Trial NCT06465745	4C Medical Technologies, Inc.	N/A
Recruiting	Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation NCT06805253	Petrovsky National Research Centre of Surgery	—
Completed	Post-market Safety and Performance Outcomes of the VIVERE® Bovine Pericardial Bioprosthetic Valve NCT06959836	Braile Biomedica Ind. Com. e Repr. Ltda.	—
Recruiting	GISE Registry of Transcatheter Treatment of Mitral Valve Regurgitation With the MitraClip G4 NCT05455489	Fondazione GISE Onlus	—
Withdrawn	Structural Heart and Valve Network PROSPECTIVE Registry NCT03928639	National Heart, Lung, and Blood Institute (NHLBI)	—
Completed	Aortic or Mitral Valve Replacement With the Braile Biomédica® Bovine Pericardium Valvular Bioprosthesis NCT05902897	Braile Biomedica Ind. Com. e Repr. Ltda.	—
Unknown	A Prospective, Multicenter Study to Evaluate the JensClip Transcatheter Valve Repair System NCT05417945	Jenscare Scientific	N/A
Completed	Chordal Repair for Transcatheter Mitral Valve Repair (TMVr) NCT04281940	Pipeline Medical	N/A
Recruiting	Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY) NCT05051033	Annetine Gelijns	N/A
Active Not Recruiting	Real World Study of the Tendyne™ Mitral Valve System to Treat Mitral Regurgitation NCT04818502	Abbott Medical Devices	—
Completed	Mi-thos® Transcatheter Mitral Valve Replacement(First-in-Man Study) NCT05784337	Shanghai NewMed Medical Co., Ltd.	N/A
Recruiting	Mi-thos® Transcatheter Mitral Valve Replacement Study NCT04195984	Shanghai NewMed Medical Co., Ltd.	N/A
Recruiting	First-In-Human Clinical Study for Treatment of Severe Mitral Valve INsufficiency With Epygon™ TRanscatheter Mi NCT04775108	Epygon	N/A
Completed	Transcatheter Mitral Valvuloplasty Pilot Study NCT04351984	Duk-Woo Park, MD	—
Recruiting	The Prospecive OBSERVational Munich Interventional MITRAl-Valve Registry NCT04577248	Deutsches Herzzentrum Muenchen	—
Active Not Recruiting	MitraClip REPAIR MR Study NCT04198870	Abbott Medical Devices	N/A
Completed	Validation of the EuroSCORE II in Open and Trans-catheter Mitral Valve Repair. NCT05714228	Michele De Bonis	—
Active Not Recruiting	MitraClip EXPAND G4 Study NCT04177394	Abbott Medical Devices	—
Unknown	AltaValve Early Feasibility Study Protocol NCT03997305	4C Medical Technologies, Inc.	N/A
Unknown	OPtimisation of Surgical Repair for Treating Insufficiency of the MItral Valve - Safety and Effectiveness Eval NCT03908983	Kephalios	N/A
Unknown	The Conveyor Study NCT03893578	Synecor, LLC	N/A
Completed	The MitraClip® EXPAND Study of the Next Generation of MitraClip® Devices NCT03502811	Abbott Medical Devices	—
Completed	MitraClip NT System Post-marketing Surveillance Study - Japan NCT03500692	Abbott Medical Devices	—
Active Not Recruiting	PARTNER 3 Trial - Mitral Valve in Valve NCT03193801	Edwards Lifesciences	N/A
Completed	OPtimisation of Surgical Repair for Treating Insufficiency of the MItral Valve - Safety Evaluation NCT03842397	Kephalios	N/A
Recruiting	Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Sympto NCT03242642	Medtronic Cardiovascular	N/A
Completed	Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Funct NCT07227675	Abbott Medical Devices	N/A
Completed	HighLife™ Transcatheter Mitral Valve Replacement System Study NCT02974881	HighLife SAS	N/A
Completed	The CLASP Study Edwards PASCAL TrAnScatheter Mitral Valve RePair System Study NCT03170349	Edwards Lifesciences	N/A
Terminated	Safety and Performance Study of the Harpoon Mitral Valve Repair System NCT03285724	Edwards Lifesciences	N/A
Completed	Coronary and Structural Interventions Ulm - Transcatheter Mitral Valve Repair (CSI-Ulm-TMVR) NCT03104660	University of Ulm	N/A
Completed	Tiara™ Transcatheter Mitral Valve Replacement Study NCT03039855	Shockwave Medical, Inc.	N/A
Withdrawn	CardiAQ-Edwards™ Transcatheter Mitral Valve Replacement (TMVR) Study NCT02722551	Edwards Lifesciences	Phase 1 / Phase 2
Completed	MERIT Study - Mistral Percutaneous Mitral Valve Repair FIM Study NCT02948231	Mitralix	N/A
Unknown	Mitral Valve Replacement With MValve Dock and Lotus NCT02719912	MValve Technologies Ltd	N/A
Unknown	Caisson Transcatheter Mitral Valve Replacement (TMVR) System Early Feasibility Study NCT02768402	Caisson Interventional LLC	N/A
Completed	CE Mark Study for the Harpoon Medical Device NCT02768870	Edwards Lifesciences	N/A
Completed	CE Mark Study for the Harpoon Medical Device in Poland NCT02432196	Edwards Lifesciences	N/A
Completed	AVJ-514 Japan Trial NCT02520310	Abbott Medical Devices	N/A
Completed	The Role of Myocardial Fibrosis in Degenerative Mitral Regurgitation NCT02355418	University Hospital Birmingham NHS Foundation Trust	—
Completed	Safety and Early Feasibility Study of the Harpoon Medical Device (EFS) NCT02771275	Edwards Lifesciences	N/A
Active Not Recruiting	Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System NCT02276547	Shockwave Medical, Inc.	N/A
Completed	Expanded Clinical Study of the Tendyne Mitral Valve System NCT02321514	Abbott Medical Devices	N/A
Unknown	Hemodynamic Stress Test in Severe Mitral Regurgitation (HEMI) NCT02961647	Odense University Hospital	—
Completed	Cardiopulmonary Exercise Testing in Severe Mitral Regurgitation NCT03154034	University Hospital Regensburg	—
Recruiting	STS/ACC TVT Registry Mitral Module NCT02245763	American College of Cardiology	—
Unknown	Treatment of Heart Failure and Associated Functional Mitral Valve Regurgitation NCT02302872	Mvrx, Inc.	N/A
Unknown	Mitralign Percutaneous Annuloplasty System for Chronic Functional Mitral Valve Regurgitation NCT01740583	Mitralign, Inc.	N/A
Unknown	Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Funct NCT01626079	Abbott Medical Devices	N/A
Completed	Atrioventricular Valve Regurgitation Vena Contracta; Echo Versus MRI NCT01504880	Medical College of Wisconsin	—
Completed	New Techniques to Evaluate Mitral Regurgitation NCT01063322	National Heart, Lung, and Blood Institute (NHLBI)	—
Unknown	Pilot Study of Lovaza (Omega 3 Fatty Acids) to Improve Cardiac Antioxidant/Anti-inflammatory Profile Before Ca NCT01046604	East Carolina University	Phase 4
Completed	Safety and Performance Study of the NeoChord Device NCT01777815	NeoChord	N/A
Completed	Real World Expanded Multicenter Study of the MitraClip® System (REALISM) NCT01931956	Abbott Medical Devices	N/A
Unknown	Dynamic Annuloplasty System With Activation for the Treatment of Mitral Regurgitation NCT00833014	MiCardia Corporation	Phase 2
Completed	A Study of Percutaneous Repair of Functional Mitral Regurgitation Using the Ancora Heart, Inc. AccuCinch® Vent NCT00800046	Ancora Heart, Inc.	N/A
Unknown	VIVID - Valvular and Ventricular Improvement Via iCoapsys Delivery - Feasibility Study NCT00512005	Myocor	Phase 1
Completed	Safety and Efficacy Study of the Sorin 3D Annuloplasty Ring For Mitral Repair NCT00567853	Sorin Group USA, Inc.	Phase 3
Completed	Magna® Mitral Pericardial Bioprostheses Post-Approval Study Protocol NCT00853632	Edwards Lifesciences	N/A
Completed	Mitral Adjustable Annuloplasty Ring Feasibility and Safety Study NCT00554151	Abbott Medical Devices	N/A
Completed	Aortic or Mitral Valve Replacement With the Biocor and Biocor Supra NCT00636987	Abbott Medical Devices	N/A
Completed	EVEREST II Pivotal Study High Risk Registry (HRR) NCT01940120	Abbott Medical Devices	N/A
Completed	Effect of Etomidate on Hemodynamics and Adrenocortical Function After Cardiac Surgery NCT00415701	Insel Gruppe AG, University Hospital Bern	Phase 4
Withdrawn	Effects of Mitral Valve Repair With the Geoform Ring on Cardiomyopathy NCT00428103	Juan Crestanello, MD	N/A
Completed	Pivotal Study of a Percutaneous Mitral Valve Repair System NCT00209274	Abbott Medical Devices	N/A
Completed	RESTOR-MV: Randomized Evaluation of a Surgical Treatment for Off-Pump Repair of the Mitral Valve NCT00120276	Myocor	Phase 2
Completed	Feasibility Study of a Percutaneous Mitral Valve Repair System. NCT00209339	Abbott Medical Devices	Phase 1 / Phase 2