NCT07296016

The Asia-Pacific Mitral & Tricuspid Valve-in-Valve/Valve-in-Ring Registry

• Status: Not Yet Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 15 (estimated)
• Sponsor: Prince of Wales Hospital, Shatin, Hong Kong · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

A significant number of patients with severe mitral and tricuspid valve disease have been previously treated with either valve repair with annuloplasty rings or valve replacement with bioprosthetic/mechanical valves. Over time, these bioprosthetic valves and rings may fail resulting in recurrence of the valvular disease. The technical aspects of a re-do operation are complex and these patients are often times at high risk for repeat open surgery. The emergence of transcatheter options may provide a safer and less invasive alternative to open surgery. Majority of the data currently exist for Western cohorts with limited longer-term outcomes. Data on this therapy is particularly lacking in the Asia-Pacific region, especially important in the light of known differences in body habitus and size.

Conditions

• Structural Heart Disease
• Mitral Valve Regurgitation

Timeline

• Start date: 2026-01-05
• Primary completion: 2035-12-31
• Completion: 2035-12-31
• First posted: 2025-12-22
• Last updated: 2025-12-22

Locations

1 site across 1 country: Hong Kong