Trials / Recruiting
RecruitingNCT06805253
Left Ventricular Reverse Remodeling Evaluation After Surgical Correction of Aortic Regurgitation
Left Ventricular Reverse Remodeling Outcomes Evaluation in Patients With Aortic Regurgitation After Surgical Treatment
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 120 (estimated)
- Sponsor
- Petrovsky National Research Centre of Surgery · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Investigators assume that surgical correction approach to functional mitral regurgitation during intervention for chronic aortic regurgitation in patients with severe enlargement of the left heart chambers influences reverse remodeling of the left ventricle (LV) in the postoperative period. It is suggested that functional mitral regurgitation (MR) provides supra-physiological left ventricle volume overload and this fact plays positive role in early-stage post-operative left ventricle volume and function recovery. LV volume, systolic and diastolic function will be monitored with echocardiography (EchoCG) along with life quality in patients with different grades of functional mitral regurgitation secondary to severe chronic aortic insufficiency after surgical treatment of aortic regurgitation.
Conditions
- Aortic Valve Regurgitation
- Mitral Valve Regurgitation
- Left Ventricle Dilated
- Left Atrium Dilated
- Systolic Left Ventricular Heart Failure
- Diastolic Heart Failure
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Not applicable - observational study | observation only |
Timeline
- Start date
- 2024-05-09
- Primary completion
- 2029-05-01
- Completion
- 2030-05-01
- First posted
- 2025-02-03
- Last updated
- 2025-06-11
Locations
2 sites across 1 country: Russia
Source: ClinicalTrials.gov record NCT06805253. Inclusion in this directory is not an endorsement.