| Not Yet Recruiting | App-Based Migraine Treatment: The Health enSuite Study NCT06797076 | IWK Health Centre | N/A |
| Not Yet Recruiting | Myotensive Extraocular Muscle Techniques Added to Manual Therapy for Migraine Without Aura NCT07254598 | Facultad de Enfermería, Fisioterapia y Podología (FEFP) | N/A |
| Not Yet Recruiting | Efficacy and Mechanism of Fu's Subcutaneous Needling Treatment for Migraine Without Aura NCT07068815 | Guangzhou University of Chinese Medicine | Phase 1 |
| Withdrawn | Healthy Living Partnerships for Veterans With Migraine NCT04373330 | Wake Forest University Health Sciences | N/A |
| Recruiting | Trial Designs for Evaluating Migraine Treatment NCT06617832 | University of Aarhus | N/A |
| Active Not Recruiting | Italian Real-life obServational Study on the effecTiveness, sAfety and Tolerability of Atogepant in Migraine P NCT06414044 | University of Florence | — |
| Recruiting | Effectiveness and Tolerability of Eptinezumab NCT06409845 | University of Florence | — |
| Recruiting | RimegepAnt effectIvenesS and tolErability as Migraine Preventive Treatment NCT06409832 | University of Florence | — |
| Completed | Mi-Helper Transnasal Cooling for Acute Treatment of Migraine NCT06051604 | CoolTech LLC | N/A |
| Unknown | Anisodine Hydrobromide For The Preventive Treatment Of Episodic Migraine NCT05416476 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 3 |
| Recruiting | Migraine Attack Pain Phase Prediction Study NCT06459635 | Fundación de Investigación Biomédica - Hospital Universitario de La Princesa | — |
| Recruiting | Responding With Evidence and Access for Childhood Headaches NCT05889624 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | Migraine With and Without Aura Characteristics and Response to Remote Electrical Neuromodulation (REN) Treatme NCT06023953 | Theranica | — |
| Completed | Ditan Acute tReatments: Effectiveness and Tolerability (DART) NCT05903040 | University of Florence | — |
| Recruiting | Gepant treAtments: EffectIveNess and tolERability (GAINER) NCT05903027 | University of Florence | — |
| Recruiting | TIzanidine for the Preventive Treatment of Episodic MigrainE （TIME） NCT05484349 | Second Affiliated Hospital, School of Medicine, Zhejiang University | Phase 3 |
| Completed | Effect of Riocigaut on Migraine Attack Induction in People With Migraine NCT05750446 | Danish Headache Center | N/A |
| Completed | Effect of Sildenafil in Individuals With Migraine Pretreated With Erenumab NCT05889455 | Danish Headache Center | N/A |
| Completed | Effect of Levcromakalim in Individuals With Migraine Pretreated With Erenumab NCT05889442 | Danish Headache Center | N/A |
| Unknown | The FreMRI Study: Advanced MRI on Migraine Patients Treated With Fremanezumab NCT06244823 | Hospital Clínico Universitario de Valladolid | Phase 4 |
| Unknown | Tailored Digital Treatment for Migraine NCT05617339 | Vastra Gotaland Region | N/A |
| Recruiting | Molecular Phenotyping of Migraine Patients According to Sex and Age Through CGRP Quantification NCT06674772 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Unknown | Monoclonal CGRP Antibodies for Migraine Prevention - a Nationwide Real Life Study NCT05281770 | Austrian Migraine Registry Collaboration | — |
| Unknown | The Involvement of ATP Sensitive Potassium Channel in Migraine Aura and Migraine Pain. NCT05565001 | Danish Headache Center | N/A |
| Terminated | Evaluation of the Efficacy of Almotriptan and Ubrogepant for the Acute Treatment of Migraine NCT05214001 | Messoud Ashina, MD | Phase 4 |
| Unknown | Brain Connectome for Acupuncture-treated Migraine Patients NCT04157192 | Centre Hospitalier Universitaire de Nīmes | N/A |
| Terminated | Evaluation of the Efficacy of Diclofenac Potassium and Rimegepant for the Acute Treatment of Migraine NCT05211154 | Danish Headache Center | Phase 4 |
| Unknown | Optical Coherence Tomography Findings in Migraine NCT05332431 | Assiut University | — |
| Completed | Effect of Sumatriptan on Levcromakalim-Induced Symptoms in Individuals With Migraine NCT05211050 | Danish Headache Center | N/A |
| Terminated | Transnasal Cooling for Migraine NCT04936061 | CoolTech LLC | N/A |
| Terminated | Efficacy of CLORazepate for the Treatment of MIGraine Attack in the Emergency Room NCT04726592 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Completed | Digital Treatment for Migraines - a Feasibility Study NCT05018572 | Vastra Gotaland Region | N/A |
| Completed | A Randomized, Double-Blind, Parallel Group, Placebo-Controlled Study to Assess STS101 in the Acute Treatment o NCT04940390 | Satsuma Pharmaceuticals, Inc. | Phase 3 |
| Completed | Effect of Ivabradine on Levcromakalim-Induced Symptoms in Individuals With Migraine Without Aura (ILIM) NCT04853797 | Danish Headache Center | N/A |
| Unknown | A Randomized Controlled Trial of Acupuncture in Treating Migraine NCT04766762 | The Third Affiliated hospital of Zhejiang Chinese Medical University | N/A |
| Recruiting | Mind Body Balance for Pediatric Migraine NCT04715685 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | A Study of the PK and Safety of Single Doses of STS101, DHE Injection and Nasal Spray in Healthy Subjects NCT05337254 | Satsuma Pharmaceuticals, Inc. | Phase 1 |
| Completed | Migraine STImulation Crisis of Migraine NCT04568252 | Remedee SA | N/A |
| Completed | A Study to Evaluate the Safety of STS101 in the Acute Treatment of Migraine NCT04406649 | Satsuma Pharmaceuticals, Inc. | Phase 3 |
| Completed | Ibuprofen in Migraine Patients NCT04533568 | Kecioren Education and Training Hospital | Phase 4 |
| Unknown | The Effect of Anti-calcitonin Gene-related Peptide (CGRP) Receptor Antibodies on the Headache Inducing Propert NCT04452929 | Danish Headache Center | N/A |
| Completed | A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate STS101 in the Acute Treatment of Migraine NCT03901482 | Satsuma Pharmaceuticals, Inc. | Phase 3 |
| Completed | The Effect of Connective Tissue Massage in Patients With Migraine NCT04171362 | Ankara Yildirim Beyazıt University | N/A |
| Completed | A Phase I Study to Study the PK and Safety of Single Doses of STS101, DHE Injection and Nasal Spray in Healthy NCT03874832 | Satsuma Pharmaceuticals, Inc. | Phase 1 |
| Completed | PACAP38 Induced Headache, Migraine and Flushing in Patients With Migraine NCT03881644 | Danish Headache Center | N/A |
| Unknown | Multiparametric Diagnostic Model of Thick-section Clinical-quality MRI Data in Detecting Migraine Without Aura NCT03570086 | Xidian University | — |
| Completed | Amylin and CGRP Head to Head Provocation in Migraine Without Aura Patients NCT03598075 | Danish Headache Center | N/A |
| Completed | Can DFN-15 Terminate Migraine With Allodynia? NCT03472378 | Hartford Hospital | Phase 2 |
| Completed | ACT Therapy for HF Migraine NCT03461874 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | N/A |
| Completed | Acupuncture In Migraine Without Aura Patients NCT04542811 | Ataturk University | N/A |
| Completed | Evaluation of a Novel Device for Treatment of Migraine Headache NCT03361423 | Theranica | N/A |
| Completed | Study the Effect of Acupuncture on Migraine Patient Without Aura Via Functional Magnetic Resonance Imaging. NCT04636359 | Beijing University of Chinese Medicine | N/A |
| Completed | PACAP27 Headache Properties in Migraine Without Aura Patients NCT03471039 | Danish Headache Center | N/A |
| Completed | Ultrasound Greater Occipital Nerve Block at C2 Level Compared to Landmark-based Greater Occipital Nerve Block NCT03478735 | Mayo Clinic | N/A |
| Completed | Integrative Migraine Pain Alleviation Through Chiropractic Therapy NCT03177616 | Harvard University Faculty of Medicine | N/A |
| Completed | Continue or Stop Applying Wet Cupping (Al-Hijamah) in Migraine NCT03479060 | Karabuk University | N/A |
| Terminated | Understanding the Pathophysiology of Migraine Pain NCT03026101 | Montefiore Medical Center | N/A |
| Completed | Efficacy Study of Acupuncture in the Prevention of Migraine Without Aura NCT02765581 | Wei Wang | N/A |
| Completed | Investigation of Vascular Inflammation in Migraine Using Molecular Nano-imaging and Black Blood Imaging MRI NCT02549898 | Danish Headache Center | N/A |
| Completed | 1H Magnetic Resonance Spectroscopy in Migraine Patients NCT04220606 | Leiden University Medical Center | N/A |
| Completed | The Effect of Histamine H1 Receptor Antagonist, Clemastin, on PACAP38 Induced Headache in Migraine Patients NCT02364453 | Song Guo | N/A |
| Completed | Investigation of Serotonin Receptor Binding in the Migraine Brain Using Positron Emission Tomography NCT02309606 | Danish Headache Center | — |
| Completed | PACAP Induced Migraine Attacks in Patients With High and Low Genetic Load NCT02158221 | Danish Headache Center | N/A |
| Completed | IndoProCaf Effervescent Tablets Effectiveness in Acute Treatment of Migraine and/or Episodic Tension-type Head NCT02115269 | Abbott | — |
| Completed | CGRP Induced Migraine Attacks in Patients With High and Low Genetic Load NCT01924052 | Danish Headache Center | N/A |
| Completed | Impact of a Nurse for Migraine Management: the IMPACT Project NCT01804517 | Notre-Dame Hospital, Montreal, Quebec, Canada | — |
| Completed | Is Chiropractic Spinal Manipulative Therapy an Efficient Treatment Option for Migraine NCT01741714 | University Hospital, Akershus | N/A |
| Completed | Efficacy and Safety of Oral Sumatriptan Plus Oral Promethazine in Migraine Treatment NCT01814189 | Shahid Beheshti University of Medical Sciences | Phase 3 |
| Unknown | Investigation of the Blood-brain and Blood-dura Barrier Durin Migraine Attacks Using MRI NCT02202486 | Glostrup University Hospital, Copenhagen | — |
| Completed | Acupuncture for Migraine Prophylaxis NCT01687660 | Li ying | N/A |
| Withdrawn | The Impact of Triptan and Doxycycline on Neuroinflammatory Biomarkers in Acute Migraine NCT01653522 | The Cleveland Clinic | N/A |
| Completed | Intravenous Ketorolac and Metoclopramide for Pediatric Migraine in the Emergency Department NCT01596166 | University of Alberta | Phase 4 |
| Completed | Effect of PACAP38/VIP on Migraineurs Measured by Magnetic Resonance NCT01471990 | Glostrup University Hospital, Copenhagen | N/A |
| Unknown | Preventive Treatment of Episodic and Chronic Migraine NCT01319825 | California Medical Clinic for Headache | Phase 4 |
| Completed | Study of the Safety and Effectiveness of NXN-188 for the Treatment of Migraine Headache Without Aura NCT00959751 | NeurAxon Inc. | Phase 2 |
| Completed | Candesartan Versus Propranolol for Migraine Prevention NCT00884663 | Norwegian University of Science and Technology | Phase 2 / Phase 3 |
| Terminated | A Study of a Melatonin Receptor Agonist to Prevent Migraine NCT00739024 | Swedish Medical Center | Phase 2 |
| Completed | Dose Ranging Study of the Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache NCT00534560 | Minster Research Ltd | Phase 2 |
| Unknown | Efficacy and Safety Clinical Trial of Intranasal AST-726 for the Prevention of Migraine NCT00285402 | Ariston Pharmaceuticals, Inc. | Phase 2 |
| Completed | Maxalt 10mg Plus Caffeine 75mg in the Acute Treatment of Migraine Headache NCT00471952 | Diamond Headache Clinic | Phase 3 |
| Completed | PACAP38´s (Pituitary Adenylate Cyclase-Activating Polypeptide) Headache Inducing Characteristics and Effects o NCT00380263 | Danish Headache Center | N/A |
| Completed | Functional MRI (fMRI) in CGRP Induced Migraine NCT00363532 | Danish Headache Center | N/A |
| Completed | TREXIMET (Formerly Known as TREXIMA) for the Acute Treatment of Probable Migraine (ICHD-II 1.6.1) NCT00387881 | GlaxoSmithKline | Phase 3 |
| Completed | Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache NCT00311662 | Minster Research Ltd | Phase 2 |
| Completed | Study to Evaluate the Efficacy and Safety of Dronabinol Metered Dose Inhaler (MDI) in Acute Treatment of Migra NCT00123201 | Solvay Pharmaceuticals | Phase 2 |
| Completed | Evaluation of the Efficacy and Safety of Laxymig® as Prophylactic Treatment in Patients With Migraine NCT00334178 | Lotus Pharmaceutical | Phase 3 |
| Completed | Eletriptan Provides Consistent Migraine Relief: Results Of A Within-Patient Multiple-Dose Study NCT01859481 | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | Phase 3 |
| Unknown | Cortical Reorganisation in Patients With Primary Headache Disorders NCT00263991 | Danish Headache Center | — |