| Not Yet Recruiting | Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD NCT07348783 | Karolinska Institutet | N/A |
| Recruiting | Light Exposure, Migraine Outcomes, and Sleep Quality NCT07476053 | Arizona State University | N/A |
| Enrolling By Invitation | Assessment of the Impact of Headache on the Employee Population of Libbs Pharmaceutical Ltd NCT07295587 | Libbs Farmacêutica LTDA | — |
| Recruiting | Yogabased Movements for Primary Headaches (Migraine and/or Cluster Headache) - YOURHEAD - a Pilot Study NCT07292090 | Karolinska Institutet | N/A |
| Active Not Recruiting | The Impact of Acupuncture on Biomarkers of Brain Injury and Inflammatory Response in Migraine NCT07292506 | University Medical Centre Ljubljana | N/A |
| Completed | Evaluation of a Wearable Device for Acute Treatment of Migraines NCT07015125 | Hinge Health, Inc | N/A |
| Recruiting | Neuro-Complex & Multi Supplements for Migraine Prevention NCT07015411 | Benfida, a department of Handi-Move | N/A |
| Completed | Cooling to Alleviate Migraine #3 NCT06874361 | Mi-Helper, Inc. | N/A |
| Active Not Recruiting | Autonomic Dysfunction in Patients With Migraine: Cardiovascular and Neurophysiology Assessment NCT06798259 | Beni-Suef University | — |
| Recruiting | Vitamin K2 Supplementation in Adult Episodic Migraine NCT05943457 | Sola Aoun Bahous, M.D. Ph.D. | N/A |
| Recruiting | A Comparison of Biodegradable and Metal Occluders in Patients With PFO and Migraine NCT06203873 | Chinese Academy of Medical Sciences, Fuwai Hospital | N/A |
| Recruiting | Migraine Attack Pain Phase Prediction Study NCT06459635 | Fundación de Investigación Biomédica - Hospital Universitario de La Princesa | — |
| Completed | Oxygen in Migraine Treatment NCT05780671 | Ankara Ataturk Sanatorium Training and Research Hospital | — |
| Unknown | Migraine With Aura and Patent Foramen Ovale: Identification of Biomarkers to Select Patients In Whom Intervent NCT06046508 | Centro Cardiologico Monzino | — |
| Recruiting | Assessment of Oral Caffeine Intake in Changing the Severity of Acute Migraine Attack Using VAS Score Among Pat NCT07022496 | Ain Shams University | Phase 4 |
| Recruiting | Molecular Phenotyping of Migraine Patients According to Sex and Age Through CGRP Quantification NCT06674772 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Completed | Effectiveness and Acceptability of MINDFULNESS by Smartphone, for Patients with Chronic Migraine and Medicatio NCT04389372 | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | Phase 4 |
| Completed | Ketone for Migraine Prevention NCT05085483 | Société des Produits Nestlé (SPN) | N/A |
| Completed | Repeat Dosing of Psilocybin in Migraine Headache NCT04218539 | Yale University | Phase 1 |
| Completed | TelemEdiciNe-bAsed Cognitive TherapY for Migraines NCT04613362 | VA Office of Research and Development | N/A |
| Withdrawn | Cefaliv® Compared to Neosaldina® in the Treatment of Migraine Attacks NCT02706015 | Ache Laboratorios Farmaceuticos S.A. | Phase 3 |
| Unknown | Automated Variable Pattern Insufflator Device (AVPI) for the Acute Treatment of Migraine NCT04584762 | Nocira, LLC | N/A |
| Unknown | Effectiveness of Education and Relaxation Program on Migraine Related Disability in Patients Attending Headach NCT05039996 | Ain Shams University | N/A |
| Unknown | Peri-neural Electrical Dry Needling Migraine Treatment Study NCT04252391 | Wheaton Franciscan Healthcare | N/A |
| Completed | Mesotherapy Versus Systemic Therapyin Treatment of Migraine Headache NCT04519346 | Ataturk University | N/A |
| Completed | A Study to Evaluate the Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache NCT03971071 | Amgen | Phase 4 |
| Completed | Assessment of Prolonged Safety and tOLerability of in Migraine Patients in a Long-term OpeN-label Study NCT04084314 | Novartis Pharmaceuticals | Phase 4 |
| Completed | Comparative Study Between Valproate and Memantine in the Prophylactic Management of Episodic Migraine. NCT04698525 | Universidad Autonoma de San Luis Potosí | Phase 3 |
| Completed | Music Intervention on Migraine Headaches NCT03763058 | Association de Musicothérapie Applications et Recherches Cliniques | N/A |
| Completed | Safety and Tolerability of POD-DHE (INP104) in Migraine (STOP 301) NCT03557333 | Impel Pharmaceuticals | Phase 3 |
| Completed | Psilocybin for the Treatment of Migraine Headache NCT03341689 | Yale University | Phase 1 |
| Completed | Bioavailability of DHE Administered by I123 POD Device, IV Injection, and Migranal Nasal Spray in Healthy Adul NCT03401346 | Impel Pharmaceuticals | Phase 1 |
| Terminated | Acute Stress Response in Migraine Sufferers NCT03099070 | Massachusetts General Hospital | N/A |
| Completed | Intravenous Fluid Therapy for the Treatment of Emergency Department Patients With Migraine Headache NCT02933060 | The Cooper Health System | Phase 2 / Phase 3 |
| Completed | Efficacy, Tolerability, and Safety of DFN-15 NCT03009019 | BioDelivery Sciences International | Phase 3 |
| Completed | Efficacy, Tolerability, and Safety Study of DFN-15 NCT03006276 | BioDelivery Sciences International | Phase 3 |
| Unknown | Study of Low-level Laser Therapy in the Acute Treatment of Migraine NCT02969642 | The San Francisco Clinical Research Center | Phase 2 |
| Terminated | Migraine and Homeostasis:What Can we Learn From Glucose NCT03097536 | Beth Israel Deaconess Medical Center | N/A |
| Unknown | Auricular Acupuncture vs SOC in Migraine HA NCT02681211 | University of Louisville | N/A |
| Completed | Testing myWHI: Online Self-guided Programs for Migraine NCT02710942 | IWK Health Centre | N/A |
| Unknown | IM Ketorolac vs Cambia for the Acute Treatment of Severe Migraine NCT02664116 | Scripps Health | Phase 4 |
| Terminated | Intranasal Cooling for Symptomatic Relief of Migraine NCT02375789 | Cumbria Partnership NHS Foundation Trust | N/A |
| Completed | Ticagrelor Therapy for RefrACTORy Migraine Study NCT02518464 | Columbia University | Phase 4 |
| Unknown | Clinical Decision Rule for Pediatric Intracranial Pathology NCT02742272 | Children's Hospitals and Clinics of Minnesota | — |
| Completed | Investigation of Vascular Inflammation in Migraine Using Molecular Nano-imaging and Black Blood Imaging MRI NCT02549898 | Danish Headache Center | N/A |
| Completed | Treatment Sleep Bruxism With the Luco Hybrid OSA Appliance NCT02882880 | Luco Hybrid OSA Appliance Inc. | N/A |
| Completed | Relief of Migraine Pain Through Electro Stimulation NCT02453399 | Theranica | N/A |
| Completed | Low- Dose Propofol Infusion as an Abortive Treatment for Migraine Headaches in Pediatric Patients NCT02485418 | University of Texas Southwestern Medical Center | N/A |
| Completed | A Preliminary Investigation of the Efficacy of Aromatherapy in Reducing Discomfort in Youth With Chronic Heada NCT02440997 | Children's Mercy Hospital Kansas City | N/A |
| Terminated | Low-dose Propofol for the Treatment of Severe Refractory Migraine Headache in the Emergency Department NCT02492295 | Albert Einstein Healthcare Network | N/A |
| Completed | A Study of Galcanezumab (LY2951742) in Participants With Migraine Headache NCT02163993 | Eli Lilly and Company | Phase 2 |
| Unknown | Effect of "Sekanjabin e Safarjali" (Quince Oxymel) in the Prevention of Migraine Attacks NCT02179775 | Shiraz University of Medical Sciences | N/A |
| Completed | Ibudilast in the Treatment of Patients With Chronic Migraine. NCT01389193 | Parisa Gazerani | Phase 1 |
| Completed | Low-dose Propofol for Pediatric Migraine NCT01604785 | Oregon Health and Science University | Phase 2 / Phase 3 |
| Withdrawn | The Impact of Triptan and Doxycycline on Neuroinflammatory Biomarkers in Acute Migraine NCT01653522 | The Cleveland Clinic | N/A |
| Completed | A Study of LY2951742 in Participants With Migraine NCT01625988 | Eli Lilly and Company | Phase 2 |
| Completed | Neurostimulation Device for Treatment of Migraine Headache NCT01630044 | Scion NeuroStim | N/A |
| Unknown | Chiropractic and Acupressure for Headaches NCT01509326 | Canadian Memorial Chiropractic College | Phase 2 / Phase 3 |
| Unknown | The Efficacy and Safety of Intra-oral Topical Ketoprofen for the Treatment of Acute Migraine NCT01228552 | Behar, Caren, M.D. | Phase 3 |
| Terminated | Integrating Acupuncture Into the Management of Migraines NCT01481103 | National University of Health Sciences | N/A |
| Completed | Electrical Stimulation of the Sphenopalatine Ganglion for the Treatment of Migraine Headaches NCT01294046 | The Cleveland Clinic | N/A |
| Completed | Safety & Efficacy of a Single Dose of Sumatriptan Powder Delivered Intranasally With the Bi-directional Device NCT01462812 | Optinose US Inc. | Phase 3 |
| Terminated | A Study in Migraine Prevention NCT01184508 | Eli Lilly and Company | Phase 2 |
| Completed | Zomig - Treatment of Acute Migraine Headache in Adolescents NCT01211145 | AstraZeneca | Phase 4 |
| Completed | Greater Occipital Nerve Block for Migraine Prophylaxis NCT00915473 | Mayo Clinic | Phase 4 |
| Unknown | Treximet in Acute Migraine Headache: Assessing Cognitive Function NCT00837044 | Neurological Research Center | N/A |
| Completed | Staccato Loxapine in Migraine (Out Patient) NCT00825500 | Alexza Pharmaceuticals, Inc. | Phase 2 |
| Terminated | Study in Participants With Acute Migraines Headaches NCT00804973 | Eli Lilly and Company | Phase 2 |
| Completed | Cupping and Serkangabin Versus Conventional Migraine Treatment NCT01476930 | Birjand University of Medical Sciences | Phase 4 |
| Completed | Zolmitriptan Nasal Spray Versus Eletriptan in the Acute Treatment of Migraine NCT01276977 | California Medical Clinic for Headache | N/A |
| Unknown | Effect of Dexamethasone on Migraine Headache NCT00733382 | Shiraz University of Medical Sciences | Phase 1 |
| Completed | A Study on the Usability of the Needle-free Intraject® System in Adult Patients During Acute Migraine Attack NCT00530517 | Zogenix, Inc. | Phase 2 |
| Unknown | Efficacy and Safety Clinical Trial of Intranasal AST-726 for the Prevention of Migraine NCT00285402 | Ariston Pharmaceuticals, Inc. | Phase 2 |
| Terminated | A Double-Blind Placebo-Controlled Trial of Rozerem in Migraine Headaches NCT00391755 | Charlottesville Neuroscience | Phase 4 |
| Completed | Staccato Prochlorperazine in Migraine (Out Patient) NCT00422812 | Alexza Pharmaceuticals, Inc. | Phase 2 |
| Completed | Examining the Efficacy of Kiko Exercises on the Prevention of Migraine Headaches NCT03651583 | Regional Clinical Research | EARLY_Phase 1 |
| Completed | Clinical Study Of Migraine Evolution NCT00460005 | GlaxoSmithKline | — |
| Unknown | Randomized Evaluation of Octreotide Versus Compazine for Emergency Department Treatment of Migraine Headache NCT00274170 | C.R.Darnall Army Medical Center | Phase 1 / Phase 2 |
| Terminated | Pilot Study of BOTOX for Migraine Headaches NCT00850421 | HealthPartners Institute | N/A |
| Completed | Safety and Efficacy of NPS 1776 in the Acute Treatment of Migraine Headaches NCT00172094 | Shire | Phase 2 |
| Completed | Clinical Study Examining Use of an Over-the-Counter Supplement for the Prevention of Menstrually-Associated Mi NCT00203255 | Thomas Jefferson University | N/A |
| Completed | An Evaluation Of The Efficacy And Safety Of Donepezil Hydrochloride (E2020) In Migraine Prophylaxis NCT01146509 | Eisai Inc. | Phase 2 |
| Completed | A Study to Measure the Safety and Effectiveness of Zonisamide in Subjects With Migraine Headache NCT00055484 | Elan Pharmaceuticals | Phase 2 |
| Completed | A Double Blind Randomized Controlled of Placebo and Nebulized Lidocaine for Migraine Headache NCT00287781 | Kern Medical Center | N/A |
| Completed | Drug and Non-Drug Treatment Of Severe Migraine NCT00910689 | Ohio University | Phase 4 |
| Completed | Rizatriptan 5 mg and 10 mg, Sumatriptan 100 mg, and Placebo Comparison Study (0462-030) NCT00898677 | Organon and Co | Phase 3 |
| Completed | MK0462 5 mg, Sumatriptan 50 mg, and Placebo Comparison Study (0462-029) NCT00897104 | Organon and Co | Phase 3 |
| Completed | Treatment of Multiple Attacks of Acute Migraine (0462-025) NCT00899379 | Organon and Co | Phase 3 |
| Completed | MK0462 in Treatment of Migraine With Recurrence (MK0462-022) NCT00897949 | Organon and Co | Phase 3 |