NCT01276977

Zolmitriptan Nasal Spray Versus Eletriptan in the Acute Treatment of Migraine

Zolmitriptan Nasal Spray VS Eletriptan in the Acute Treatment of Migraine

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: California Medical Clinic for Headache · Academic / Other
• Sex: All
• Age: 15 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to Compare the efficacy of zolmitriptan 5 mg nasal spray vs. eletriptan 40 mg tablet in the acute treatment of migraine. To develop and evaluate a set of importance weights for a predefined set of treatment attributes for migraine suffers using zolmitriptan 5 mg nasal spray vs. eletriptan 40 mg tablet. To contrast the efficacy of zolmitriptan 5 mg nasal spray vs. eletriptan 40 mg tablet at early time points. To analyze the patterns of self-reported tolerability of migraine sufferers using zolmitriptan 5 mg nasal spray vs. eletriptan 40 mg tablet.

Detailed description

An open-label, randomized, cross-over study comparing the efficacy of zolmitriptan 5 mg nasal spray with eletriptan 40 mg tablet at early time points. Satisfaction endpoints include global assessment of preference, overall satisfaction and effectiveness as well as tolerability of both medications.

Conditions

• Acute Migraine
• Migraine Headache
• Headache Disorders

Interventions

Type	Name	Description
DRUG	Zolmitriptan 5 mg Nasal Spray	Patients will treat 2 migraine attacks with zolmitriptan 5 mg nasal spray and 2 migraine attacks with eletriptan.
DRUG	Eletriptan 40 mg tablet	Patients will treat 2 migraine attacks with Eletriptan and 2 migraine attacks with zolmitriptan 5 mg nasal spray

Timeline

• Start date: 2008-04-01
• Primary completion: 2010-12-01
• Completion: 2010-12-01
• First posted: 2011-01-14
• Last updated: 2011-01-14

Locations

1 site across 1 country: United States