| Not Yet Recruiting | Human Models of Selective Insulin Resistance: Pancreatic Clamp NCT06558422 | Columbia University | Phase 1 |
| Not Yet Recruiting | How Abnormal Function of Fat Tissue in Type 1 Diabetes Contributes to Fat in the Liver NCT07133854 | Université de Sherbrooke | N/A |
| Not Yet Recruiting | SMART Diets for MASLD NCT07459504 | Corewell Health West | Phase 2 |
| Not Yet Recruiting | Samsung S-Viscosity vs Canon Dispersion Slope in Steatotic Liver Disease (SAVID-SLD) NCT07530419 | Seoul National University Hospital | — |
| Not Yet Recruiting | Impact of Circadian Exercise on Metabolic Dysfunction-Associated Steatotic Liver Disease in Postmenopausal Wom NCT07386665 | Universidad de Almeria | N/A |
| Recruiting | A Large Language Model-based Chatbot for Alcohol Reduction in Patients With Metabolic Alcohol-Related Liver Di NCT07450144 | The University of Hong Kong | N/A |
| Recruiting | Advanced Fibrosis Detection for MASLD in Primary Care NCT07159386 | Medical University of South Carolina | N/A |
| Not Yet Recruiting | MPV as a Predictor for ACS in Patients With MASLD NCT07487571 | Sohag University | — |
| Not Yet Recruiting | Using Digital Twin Technology and Clinical Decision Support Systems to Improve the Early Detection, Personalis NCT07430501 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Recruiting | Efficacy and Safety of Rifaximin-α in Treating MASLD NCT07381257 | Shanghai Changzheng Hospital | EARLY_Phase 1 |
| Not Yet Recruiting | Ultrasound Liver Imaging for Classification of Metabolic Dysfunction-associated Steatotic Liver Disease NCT07373769 | University of British Columbia | — |
| Not Yet Recruiting | Improving Diagnostic Safety Through STeatosis Identification, Risk Stratification, and Referral in the ED NCT06944353 | Northwestern University | N/A |
| Enrolling By Invitation | Assessment of Non-Invasive Testing in Major Liver-Related Outcomes NCT06986447 | HRI-MAIL-NIT | — |
| Recruiting | A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease ( NCT07165028 | Eli Lilly and Company | Phase 3 |
| Completed | Digital Pathology and AI for Liver Outcomes in MASLD (DPAILO-2) NCT06493253 | PharmaNest, Inc | — |
| Completed | Digital Pathology and AI for Liver Outcomes in MASLD NCT06344364 | PharmaNest, Inc | — |
| Not Yet Recruiting | Clinical Efficacy of Pegylated Interferon Alpha-2b Combined With Nucleos(t)Ide Analogues in the Treatment of C NCT07071636 | Shenzhen Third People's Hospital | Phase 4 |
| Not Yet Recruiting | Prognostic Model for MASLD Related Cirrhosis NCT07082751 | Beijing Friendship Hospital | — |
| Not Yet Recruiting | Reducing Barriers to Lifestyle Modification for Newly Diagnosed MASLD NCT06483711 | Stanford University | N/A |
| Recruiting | Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial NCT06138821 | Pichamol Jirapinyo, MD, MPH | N/A |
| Recruiting | Quantitative Ultrasound(DeepUSFF) vs MRI-PDFF for Liver Fat Assessment in MASLD NCT07192159 | Seoul National University Hospital | N/A |
| Not Yet Recruiting | Effect of In-Place Slow Jogging on Metabolic Dysfunction-Associated Steatotic Liver Disease NCT06994234 | Shanghai East Hospital | N/A |
| Recruiting | The Establishment of Hong Kong Diabetes Steatotic Liver Disease Register NCT07437157 | Chinese University of Hong Kong | — |
| Recruiting | The Impact of Pectin Supplementation on Systematic Inflammation Pathway, Gut Microbiome, and Metabolic Health NCT07093346 | University of Nottingham | N/A |
| Recruiting | Aspirin for Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease NCT06935994 | Taichung Veterans General Hospital | Phase 2 |
| Not Yet Recruiting | Digital Diet and Exercise Intervention to Reduce Liver Fibrosis in Metabolic Dysfunction-associated Steatotic NCT06920316 | St. George's Hospital, London | Phase 4 |
| Recruiting | A Study to Evaluate ALN-CIDEB in Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Dise NCT06836609 | Regeneron Pharmaceuticals | Phase 1 |
| Enrolling By Invitation | Effect on Body Weight Reduction of a Behavioral Intervention on Lifestyle Using a Digital Nutritional Program NCT07456332 | Hospital Universitari de Bellvitge | N/A |
| Recruiting | Study of the Link Between MASH ( Metabolic Dysfunction-Associated Steatohepatitis) and MAMs (Mitochondria-Asso NCT06868992 | Hospices Civils de Lyon | — |
| Enrolling By Invitation | Metabolically Healthy Obesity Increases the Risks of MASLD and Hyperuricemia NCT07001865 | Ningbo No. 1 Hospital | — |
| Recruiting | Accelerated Biological Aging is Associated With Increased Risk of T2DM in the MASLD Population NCT06984510 | Ningbo No. 1 Hospital | — |
| Enrolling By Invitation | Effects of iGlarLixi Versus iGlar on Liver Fat Content in Patients With Type 2 Diabetes Mellitus Combined With NCT07274644 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | Phase 4 |
| Enrolling By Invitation | Effects of Different Exercises on Intrahepatic Lipid in Patients With Metabolic Dysfunction-associated Steatot NCT06994871 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | N/A |
| Not Yet Recruiting | Korean Health Screening-Based Metabolic Dysfunction-Associated Steatotic Liver Disease Registry NCT06843421 | Korea University | — |
| Withdrawn | A Phase 3 Study Evaluating the Safety and Efficacy of Denifanstat in Patients With MASLD and MASH NCT06692283 | Sagimet Biosciences Inc. | Phase 3 |
| Recruiting | Effect of Indianized Version of Mediterranean Diet vs. Low Fat Diet on Hepatic Steatosis in Overweight Childre NCT06768216 | Institute of Liver and Biliary Sciences, India | N/A |
| Not Yet Recruiting | Clinical Classification of MAFLD Based Liver Biopsy NCT06795646 | Beijing Friendship Hospital | — |
| Active Not Recruiting | Feasibility of the Paso Program for Patients With Metabolic Dysfunction Associated Steatotic Liver Disease NCT06854185 | Baylor College of Medicine | N/A |
| Recruiting | Development of Microbial Therapeutics for Metabolic-associated Fatty Liver Disease: From Mechanistic Investiga NCT06873165 | National Taiwan University Hospital | N/A |
| Recruiting | Developing Microbial Therapy for MASLD: From Mechanism to Clinical Validation NCT07488975 | Leeuwenhoek Laboratories Co. Ltd. | Phase 1 |
| Recruiting | COmmencing Menopausal HOrmone Replacement Therapy and the Effect on Metabolic-dysfunction Associated Steatotic NCT06704516 | University of Oxford | Phase 1 |
| Not Yet Recruiting | Henagliflozin on Liver Fibrosis in Patients with MASLD and T2DM NCT06762223 | Xiqiao Zhou | Phase 4 |
| Recruiting | Effect of a GnRH Analog on Hepatic Steatosis NCT06523530 | Aristotle University Of Thessaloniki | Phase 4 |
| Not Yet Recruiting | Liver Fibrosis Assessment in Diabetic Patients NCT06694974 | National Taiwan University Hospital | N/A |
| Recruiting | Prognostic Factors for HCC and Liver Transplantation in Patients With MASLD/MASH NCT06813508 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Not Yet Recruiting | Impact of Live Streaming Exercise on Liver Health in MASLD Pregnant Women NCT06682663 | Peking University | N/A |
| Not Yet Recruiting | Targeting the Skeletal Muscle to Treat Metabolic Dysfunction-associated Steatotic Liver Disease NCT06506513 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Recruiting | Metabolic Features Effects on FAST Score in MASLD Patients NCT06867419 | Tanta University | — |
| Not Yet Recruiting | Study of Metabolic Dysfunction-Associated Steatotic Liver Disease Among Sohag University Employees NCT06536933 | Sohag University | — |
| Recruiting | Hyperbaric Oxygen Therapy for Metabolic Dysfunction-associated Steatotic Liver Diseases NCT06619808 | Jinling Hospital, China | N/A |
| Completed | Alternate Dosing Study of MK-6024 in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MAS NCT06482112 | Merck Sharp & Dohme LLC | Phase 2 |
| Recruiting | Pattern of Cardiac Arrhythmia in Patients With MASLD NCT06490432 | Sohag University | — |
| Active Not Recruiting | A Clinical Study of Efinopegdutide in People With Compensated Cirrhosis Due to Steatohepatitis (MK-6024-017) NCT06465186 | Merck Sharp & Dohme LLC | Phase 2 |
| Recruiting | Fecal Microbiota Analysis of PNPLA3 Polymorphism in Hispanic Patients With MASLD NCT06495333 | Fundacion de Investigacion Science and Education | — |
| Recruiting | Effect of High Intensity Exercise Rehabilitation on Liver Function and Insulin Sensitivity in Patients With MA NCT06359444 | University Ghent | N/A |
| Unknown | Risk Factors and Impact MASLD in Patients With IBD NCT06328452 | Assiut University | — |
| Enrolling By Invitation | Guerbet Liver Fibrosis NCT06703450 | Icahn School of Medicine at Mount Sinai | — |
| Active Not Recruiting | Non-Invasive Diagnostic Tests for MASLD in Pediatric Population NCT06218589 | Emory University | N/A |
| Recruiting | Influence of Metabolic Syndrome on Endogenous Oxalate Synthesis NCT06735924 | University of Alabama at Birmingham | N/A |
| Completed | Probiotic Lysate (Postbiotic and Metabiotic) Supplementation for Adults MASLD Patients (DELI_MASLD Study) NCT06352697 | Bogomolets National Medical University | N/A |
| Recruiting | Liver Fat as a Dietary Target of the Chinese Medical Nutrition Therapy (CMNT) Diet for Treating Type 2 Diabete NCT07083336 | State Key Laboratory of Subhealth Intervention Technology | N/A |
| Completed | Lifestyle Habits and Metabolic Dysfunction-Associated Steatotic Liver Disease in Youth NCT07095010 | Harokopio University | — |
| Completed | The Impact of Nutrition Education and Rice Bran Supplementation on Metabolic Dysfunction-associated Steatotic NCT07524621 | Shih Chien University | N/A |
| Enrolling By Invitation | Investigating Myosteatosis in Steatotic Liver Diseases NCT06514300 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | — |
| Completed | Antidiabetic Drugs for Steatotic Liver Disease NCT03646292 | Yonsei University | Phase 4 |
| Completed | Risk Factors and Prediction Model for Liver-Related Outcomes in Elderly Patients With Steatotic Liver Disease NCT07537829 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | — |