| Not Yet Recruiting | Nutritional Ketosis Marfan NCT07495267 | Washington University School of Medicine | N/A |
| Not Yet Recruiting | Clinical and Psychosocial Factors Associated With Physical Activity Level in Adults With Marfan Syndrome NCT07419386 | University of Oviedo | — |
| Not Yet Recruiting | Multicentre Longitudinal Study of Bone Mineralisation Characteristics in Marfan Syndrome and Ehlers-Danlos Syn NCT07169669 | IRCCS Policlinico S. Donato | — |
| Enrolling By Invitation | Fibroblasts and Thoracic Aortic Aneurysms: in Vitro Characterization in With Marfan Syndrome and Genetic Aorti NCT06786754 | IRCCS Policlinico S. Donato | — |
| Recruiting | National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in B NCT06546137 | Hospital do Coracao | — |
| Completed | APPLICATION OF THERAPEUTIC PHOTOGRAPHY AND EXPRESSIVE WRITING IN THE MANAGEMENT OF PATIENTS WITH MARFAN SYNDRO NCT06872268 | IRCCS Policlinico S. Donato | N/A |
| Completed | Single-Session "Empowered Relief" Class for Marfan Syndrome and Related Conditions NCT05980104 | Stanford University | N/A |
| Active Not Recruiting | Proximal Aortopathy in Scotland - Epidemiology and Surgical Outcomes NCT05389865 | Golden Jubilee National Hospital | — |
| Completed | Mortality and Morbidity Outcomes in Marfans NCT04774172 | Barts & The London NHS Trust | — |
| Recruiting | Marfan Syndrome Moderate Exercise Trial II NCT05809323 | Baylor College of Medicine | N/A |
| Recruiting | Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Marfan Syndro NCT05838235 | University Hospital, Toulouse | N/A |
| Completed | Measurement of Heart-carotid Pulse Wave Velocity (hcPWV) by Laser Doppler Vibrometry (LDV) NCT05711693 | Institut National de la Santé Et de la Recherche Médicale, France | N/A |
| Completed | Towards Optimal Treatment of Marfan Syndrome NCT05944614 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Active Not Recruiting | Analysis of Muscular Properties in Patients With MFS and EDS NCT05720923 | IRCCS Policlinico S. Donato | — |
| Unknown | Psychological Support in Adult Patients With Marfan Syndrome NCT05712577 | IRCCS Policlinico S. Donato | — |
| Recruiting | Marfan Syndrome (MFS) and Facial Dysmorphism: Non-invasive 3D Assessment NCT05702476 | IRCCS Policlinico S. Donato | — |
| Completed | Clinical Signs and Activity Limitations Associated With Dural Ectasia in Patients With Marfan Disease NCT05123339 | Assistance Publique - Hôpitaux de Paris | — |
| Recruiting | Biological Collection for Marfan and Related Syndromes NCT04970459 | University Hospital, Toulouse | — |
| Recruiting | Transcriptomic Study of Adult Population With Marfan Syndrome NCT05700175 | IRCCS Policlinico S. Donato | — |
| Completed | Living With Marfan Syndrome and Your Aorta NCT04776668 | Barts & The London NHS Trust | — |
| Completed | Living With Marfans and Your Aorta: Surgical Outcomes Study NCT04776681 | Barts & The London NHS Trust | — |
| Completed | Safety and Performance of POLYTHESE® Vascular Prosthesis NCT05516043 | Perouse Medical | — |
| Completed | Effects of Personalized Training at Home Combining Endurance and Resistance in Patients Suffering From Marfan NCT04553094 | French Cardiology Society | N/A |
| Unknown | Effect on the Quality of Life of a Therapeutic Education Program in Patients With Marfan Syndrome NCT04731493 | University Hospital, Toulouse | — |
| Unknown | Genome-wide Epistasis for Cardiovascular Severity in Marfan Study NCT06257004 | University Hospital, Antwerp | — |
| Completed | Marfan Syndrome Moderate Exercise Pilot NCT04641325 | Baylor College of Medicine | N/A |
| Completed | Cardiorespiratory and Muscular Rehabilitation of Children and Young Adults With Marfan Syndrome. NCT03236571 | University Hospital, Toulouse | N/A |
| Completed | Tele-Clinic Visits in Pediatric Marfan Patients Using Parental Echo: The Future? NCT03581682 | Stanford University | N/A |
| Completed | Children and Adolescents With Marfan Syndrome: 10,000 Healthy Steps and Beyond NCT03567460 | Stanford University | N/A |
| Unknown | Surgical Treatment of Marfan Syndrome With Subluxation Lens NCT05578469 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Active Not Recruiting | Pathogenetic Basis of Aortopathy and Aortic Valve Disease NCT03440697 | Yale University | — |
| Completed | Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes NCT02213484 | University of Colorado, Denver | — |
| Recruiting | Complex Aortic Aneurysm Repair Using Physician Modified Endografts and Custom Made Devices NCT02050113 | Andres Schanzer | N/A |
| Unknown | The Oxford Marfan Trial NCT01949233 | University of Oxford | Phase 2 |
| Unknown | Development of a Blood Test for Marfan Syndrome NCT02148900 | Shriners Hospitals for Children | — |
| Completed | Aortopathy in Persons With Bicuspid Aortic Valve, Turner and Marfan Syndrome NCT01760668 | University of Aarhus | — |
| Completed | Thoracic Aortic Dilatation Syndromes NCT02111668 | University of Aarhus | — |
| Completed | Genotypes and Craniofacial Phenotypes in Orthodontic Patients With Marfan and Loeys-Dietz Syndromes NCT07360704 | Andrea Scribante | — |
| Withdrawn | Circulating Transforming Growth Factor Beta (TGF-β) in Individuals With Marfan Syndrome NCT01361087 | Ann & Robert H Lurie Children's Hospital of Chicago | Phase 3 |
| Completed | Comparison of Aliskiren vs Negative Controls on Aortic Stiffness in Patients With MFS NCT01715207 | Samsung Medical Center | Phase 3 |
| Completed | Randomized, Double-blind Study for the Evaluation of the Effect of Losartan Versus Placebo on Aortic Root Dila NCT00782327 | University Hospital, Ghent | Phase 3 |
| Completed | Clinical Variability in Marfan Syndrome NCT01707563 | Assistance Publique - Hôpitaux de Paris | N/A |
| Unknown | Atenolol Versus Losartan in the Prevention of Progressive Dilation of the Aorta in Marfan Syndrome NCT01145612 | Forteza, Albert, M.D. | Phase 3 |
| Terminated | Study of the Efficacy of Losartan on Aortic Dilatation in Patients With Marfan Syndrome NCT00763893 | Assistance Publique - Hôpitaux de Paris | Phase 3 |
| Unknown | Nebivolol Versus Losartan Versus Nebivolol+Losartan Against Aortic Root Dilation in Genotyped Marfan Patients NCT00683124 | Fondazione IRCCS Policlinico San Matteo di Pavia | Phase 3 |
| Completed | Losartan Versus Atenolol for the Treatment of Marfan Syndrome NCT00593710 | University of British Columbia | Phase 2 |
| Completed | National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions NCT01322165 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Effects of Losartan Versus Atenolol on Aortic and Cardiac Muscle Stiffness in Adults With Marfan Syndrome NCT00723801 | Brigham and Women's Hospital | Phase 3 |
| Unknown | A Randomized, Open-label, LOSARTAN Therapy on the Progression of Aortic Root Dilation in Patients With Marfan NCT00651235 | National Taiwan University Hospital | Phase 2 |
| Completed | Comparison of Two Medications Aimed at Slowing Aortic Root Enlargement in Individuals With Marfan Syndrome NCT00429364 | Carelon Research | Phase 3 |
| Completed | Comparison of Medical Therapies in Marfan Syndrome. NCT01295047 | Cardiff University | Phase 4 |
| Completed | Angiotensin Converting Enzyme Inhibitors in Marfan Syndrome NCT00485368 | Bayside Health | Phase 3 |
| Completed | Studies of Heritable Disorders of Connective Tissue NCT00270686 | National Institute on Aging (NIA) | — |
| Completed | Classifying Ectopia Lentis in Marfan Syndrome Into Five Grades of Increasing Severity NCT04319107 | Hospices Civils de Lyon | — |
| Completed | Study of Heritable Connective Tissue Disorders NCT00001641 | National Human Genome Research Institute (NHGRI) | — |