| Completed | Exercise Performance on Ambient Air vs. Low-Flow Oxygen Therapy With Chronic Lung Diseases NCT06385301 | University of Zurich | N/A |
| Unknown | Determination of Posture in Patients With Restrictive and Obstructive Lung Disease NCT06306482 | Hacettepe University | — |
| Recruiting | Efficacy of EFA in Acquired Brain Injury NCT05993364 | Fondazione Don Carlo Gnocchi Onlus | N/A |
| Completed | Individualizing Treatment for Asthma in Primary Care NCT06272370 | DARTNet Institute | Phase 4 |
| Completed | Observational Bronchoscopy Video Data Collection Study With Adult Patients NCT06465797 | Ambu A/S | — |
| Completed | Diagnosing Obstructive Lung Disease With Point of Care Ultrasound NCT06251271 | Soroka University Medical Center | — |
| Withdrawn | TOBacco STOP in Chronic Obstructive Pulmonary Disease-Trial - Study Protocol NCT04088942 | Pradeesh Sivapalan | Phase 4 |
| Terminated | French Validation of the CAPTURE Case Finding Tool for Obstructive Respiratory Disease NCT05654597 | Groupe Hospitalier du Havre | — |
| Recruiting | Cough Capture as a Portal Into the Lung NCT05854563 | Albert Einstein College of Medicine | — |
| Completed | Holistic Wellbeing in COPD: Communication About Sexuality (COSY) NCT05696730 | University of Zurich | N/A |
| Terminated | Treatment Efficacy of Systemic Corticosteroids in AECOPD Patients With Higher Blood Eosinophil Levels NCT05059873 | Capital Medical University | Phase 4 |
| Recruiting | Thermotherapy Against Persistent Bacterial LUNG Infections NCT05351242 | Chronic Obstructive Pulmonary Disease Trial Network, Denmark | N/A |
| Active Not Recruiting | TCM Daoyin Therapy in Individuals At-risk for COPD NCT05940480 | Shanghai University of Traditional Chinese Medicine | N/A |
| Completed | Effects of Supervision During a Community-based Exercise Intervention (Urban Training) in Patients With COPD NCT05565872 | Universidad Complutense de Madrid | N/A |
| Not Yet Recruiting | Antibiotic Stewardship in AECOPD Through CRP-Guided Management NCT05286918 | The University of Hong Kong | N/A |
| Completed | Feasibility of Performing Peripheral Pulmonary Lesion Biopsy Using Robotic Bronchoscopy-Guided Cryoprobe NCT05399082 | Mayo Clinic | N/A |
| Unknown | Prospective, Observational Study of Wellinks Effect on COPD Hospital Readmissions NCT05330507 | Convexity Scientific Inc | — |
| Unknown | Social Media-based Bundle Care of AECOPD Patients. NCT05209607 | Beijing Chao Yang Hospital | Phase 4 |
| Completed | The Effect of Education Based on the Chronic Care Model in COPD Patients NCT05029557 | Hasan Kalyoncu University | N/A |
| Unknown | ECCO2R in the Treatment of Acute Exacerbation of COPD With Severe Hypercapnia NCT04842344 | Li Xuyan | N/A |
| Unknown | Capnography Monitoring in Ventilated Children NCT04354220 | Vincenzo Cannizzaro | — |
| Unknown | Anti-viral Effects of Azithromycin in Patients With Asthma and COPD NCT04319705 | Bispebjerg Hospital | Phase 4 |
| Completed | Preoperative Self-assessment for Cardio-pulmonary Risk Stratification NCT04156594 | Universitätsklinikum Hamburg-Eppendorf | — |
| Unknown | Respiratory Function in Patients With Post-tuberculosis Lung Impairment NCT03821285 | Università degli Studi dell'Insubria | N/A |
| Completed | Study to Evaluate Tezepelumab on Airway Inflammation in Adults With Uncontrolled Asthma (CASCADE) NCT03688074 | AstraZeneca | Phase 2 |
| Completed | Home-based Exercise Training for COPD Patients (HOMEX-2) NCT03654092 | University of Zurich | N/A |
| Unknown | Integration of Guidelines for Comorbidities NCT02928666 | Rambam Health Care Campus | N/A |
| Completed | Home-based Exercise Training for COPD Patients NCT03461887 | University of Zurich | N/A |
| Completed | Corticosteroid Reduction in COPD NCT02857842 | Chronic Obstructive Pulmonary Disease Trial Network, Denmark | Phase 4 |
| Unknown | Impacts of a Continuing Education Activity Targeted at COPD Case Managers NCT02870998 | Laval University | N/A |
| Completed | Airway Effects of Tiotropium in Patients With COPD NCT02683668 | Imperial College London | Phase 3 |
| Unknown | Effect of Atmospheric Pollution on Obstructive Lung Diseases NCT03059459 | National Council of Scientific and Technical Research, Argentina | — |
| Completed | The Leaky Lung Test NCT02306473 | University of Rochester | EARLY_Phase 1 |
| Completed | Prospective Randomized Study of Nasal High Flow in Treatment of Acute Exacerbation of Chronic Obstructive Pulm NCT02439333 | Li Xuyan | N/A |
| Completed | Preoperative Diagnostic Tests for Pulmonary Risk Assessment in COPD NCT02566343 | Universitätsklinikum Hamburg-Eppendorf | — |
| Terminated | Post-hospitalisation Nutritional Support and Gait Speed in COPD NCT02261350 | Royal Brompton & Harefield NHS Foundation Trust | Phase 3 |
| Withdrawn | TruFreeze™ Airway Obstruction: TAO STUDY NCT01903850 | CSA Medical, Inc. | Phase 4 |
| Completed | Physical Activity Augmentation Using Pedometers During Pulmonary Rehabilitation in Chronic Obstructive Pulmona NCT01719822 | Royal Brompton & Harefield NHS Foundation Trust | N/A |
| Completed | Asthma Data Innovation Demonstration Project NCT02162576 | David Van Sickle | N/A |
| Completed | Do the SPPB and 4-metre Gait Speed Predict Hospital Readmission in Patients Hospitalised for Acute Exacerbatio NCT01507415 | Royal Brompton & Harefield NHS Foundation Trust | — |
| Completed | Is the Short Physical Performance Battery a Useful Outcome Measure in Chronic Obstructive Pulmonary Disease NCT01515709 | Royal Brompton & Harefield NHS Foundation Trust | — |
| Completed | Growth, Health and Development in Children Born Extremely Preterm NCT01150071 | University of Bergen | — |
| Unknown | Efficacy of Oxygen Therapy Delivered by Systems Using Oxygen-Saving Valves in COPD Patients NCT01180803 | Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche | N/A |
| Completed | Does Positive Expiratory Pressure Mask Therapy Improve Recovery From Acute Exacerbations of Chronic Obstructiv NCT01101282 | La Trobe University | N/A |
| Completed | A Study To Investigate The Safety, Toleration And Efficacy of PF00610355 In Chronic Obstructive Pulmonary Dise NCT00808288 | Pfizer | Phase 2 |
| Completed | A Phase I Study of iPS Cell Generation From Patients With COPD NCT01860898 | Mayo Clinic | N/A |
| Withdrawn | A Study To Examine The Safety And Efficacy Of PF-00610355 In Moderately Asthmatic Subjects NCT00830427 | Pfizer | Phase 2 |
| Terminated | Interventional Cryotherapy for the Eradication of Benign Airway Disease ("ICE the BAD") NCT00747461 | CSA Medical, Inc. | Phase 4 |
| Unknown | LTOT in COPD Patients With Moderate Chronic Hypoxemia and Chronic Heart Failure NCT00668408 | Azienda Ospedaliero-Universitaria Careggi | Phase 4 |
| Completed | Viral Infections in Chronic Obstructive Pulmonary Disease (COPD) Exacerbations NCT00448604 | University Hospital, Geneva | — |
| Completed | 26 Week Efficacy, Safety and Tolerability Study of Indacaterol in Patients With Chronic Obstructive Pulmonary NCT00463567 | Novartis | Phase 2 / Phase 3 |
| Completed | Indacaterol Delivered Via a Single Dose Dry Powder Inhaler (SDDPI) in Chronic Obstructive Pulmonary Disease (C NCT00396604 | Novartis | Phase 2 / Phase 3 |
| Completed | Changes in Cytokine Levels During an Acute Exacerbation of Chronic Obstructive Pulmonary Disease NCT00281242 | University of Michigan | — |
| Completed | Innate and Adaptive Immunity in Individuals Experiencing Chronic Obstructive Pulmonary Disease Exacerbations NCT00281216 | University of Michigan | — |
| Completed | Comparison of Alveolar Macrophages in Individuals With COPD Versus Smokers With Normal Pulmonary Function NCT00281190 | University of Michigan | — |
| Completed | T Lymphocyte Cells in Individuals Experiencing an Acute Exacerbation of Chronic Obstructive Pulmonary Disease NCT00281229 | University of Michigan | — |
| Completed | Cigarette Smoke Nasal and Whole Blood Challenge in Patients With Chronic Obstructive Pulmonary Disease (COPD) NCT00159341 | Imperial College London | Phase 1 |
| Completed | Comparison of Alveolar Macrophages in Healthy Individuals Versus Individuals With COPD NCT00281203 | University of Michigan | — |
| Terminated | Method of Oxygen Delivery and the Effect on Transcutaneous PaCO2 NCT00135252 | The University of Texas Health Science Center, Houston | Phase 2 / Phase 3 |
| Completed | Aridol Challenge as a Tool to Predict Treatment Response to Inhaled Corticosteroids in COPD NCT00117182 | Syntara | Phase 2 |
| Completed | Monitoring Asthma and COPD in Primary Care NCT00542061 | Radboud University Medical Center | N/A |
| Completed | Genetic Factors That Influence Chronic Obstructive Pulmonary Disease in Hispanics NCT00106470 | University of Pittsburgh | — |
| Completed | Costs and Effects of Three Modes for Disease Management of Chronic Obstructive Pulmonary Disease in General Pr NCT00128765 | Radboud University Medical Center | N/A |
| Completed | Study of Acid Reflux in Asthma NCT00069823 | Johns Hopkins Bloomberg School of Public Health | Phase 3 |
| Completed | Supplemental Selenium and Vitamin E and Pulmonary Function NCT00063453 | Cornell University | Phase 3 |
| Completed | Yoga for Treating Shortness of Breath in Chronic Obstructive Pulmonary Disease (COPD) NCT00051792 | National Center for Complementary and Integrative Health (NCCIH) | Phase 1 / Phase 2 |
| Completed | Comparison of Two Programs to Encourage Physical Activity in Individuals With Chronic Obstructive Pulmonary Di NCT00328484 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |
| Completed | Assessing the Occupation Burden in COPD NCT00006513 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Diet and Chronic Obstructive Pulmonary Disease NCT00006419 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Effects of Chronic Ozone Exposure on Lung Function NCT00006306 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Feasibility of Retinoic Acid Treatment in Emphysema (FORTE) NCT00000621 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 2 |
| Completed | COPD on Primary Care Treatment (COOPT) NCT00184977 | Radboud University Medical Center | Phase 4 |
| Completed | Genetics of Airway Responsiveness and Lung Function NCT00005537 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | National Emphysema Treatment Trial (NETT) NCT00000606 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |
| Completed | Sources of Variability in Peak Expiratory Flow NCT00005382 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Characterization of the Pathobiology of Early Lung Destruction in Alpha 1-Antitrypsin Deficient Individuals NCT00001462 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Lung Health Study II NCT00000569 | University of Minnesota | Phase 3 |
| Completed | Longitudinal Study of Cortisol and Pulmonary Function NCT00005370 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Intervention for Resistant Pregnant Smokers NCT00005697 | The University of Texas Health Science Center, Houston | — |
| Completed | Statistical Analysis of Vlagtwedde-Vlaardingen Data Set NCT00005425 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Lay-Led Smoking Cessation Approach for Southeast Asian Men NCT00005720 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Medication Adherence in COPD--A Self-Regulation Study NCT00005717 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Emphysema: Physiologic Effects of Nutritional Support NCT00000573 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 2 |
| Completed | Epidemiology and Pulmonary Response To Organic Dust Exposure NCT00005288 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Trial of Inspiratory Muscle Rest and Exercise in Chronic Obstructive Lung Disease NCT00000571 | McGill University | Phase 3 |
| Completed | Effect of Maternal Smoking On Neonatal Lung Function NCT00005285 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Epidemiology of Airway Responsiveness NCT00005284 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Lung Health Study (LHS) I and III NCT00000568 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |
| Completed | Prospective Evaluation of Airways Reactivity NCT00005282 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Early Risk Predictors For Chronic Pulmonary Disease NCT00005281 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Clinical Study of Intermittent Positive Pressure Breathing (IPPB) NCT00000565 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |
| Completed | Nocturnal Oxygen Therapy NCT00000564 | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 |
| Completed | Specialized Center of Research in Occupational and Immunologic Lung Disease NCT00005280 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Tucson Epidemiology Study of Chronic Obstructive Lung Diseases NCT00005279 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Honolulu Heart Program NCT00005123 | National Heart, Lung, and Blood Institute (NHLBI) | — |
| Completed | Effectiveness and Cost Impact of a Telecommunications System in COPD NCT00012805 | US Department of Veterans Affairs | Phase 4 |