Trials / Completed
CompletedNCT01860898
A Phase I Study of iPS Cell Generation From Patients With COPD
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 31 (actual)
- Sponsor
- Mayo Clinic · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
As part of the long-term goal of successfully implementing tissue regeneration strategies in an individualized manner for patients with thoracic diseases including, but not limited to: cystic fibrosis, pulmonary fibrosis and pulmonary hypertension, the investigators will assess the feasibility of collecting skin biopsies from patients undergoing surgery for thoracic disease, culturing skin fibroblasts from the biopsy, and reprogramming these skin fibroblasts into induced pluripotent cells.
Conditions
- Thoracic Diseases
- Respiratory Tract Diseases
- Cancer of Lung
- Cancer of the Lung
- Lung Cancer
- Lung Diseases, Obstructive
- COPD
- Pulmonary Emphysema
- Neoplasms, Lung
- Neoplasms, Pulmonary
- Pulmonary Cancer
- Pulmonary Neoplasms
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Small Cell
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Skin Biopsy | Biopsy samples will be taken as a 2mm x 2cm excision of a wedge of skin at the edge of the incision during your surgery at the Mayo Clinic Rochester. Such excisions are frequently done as part of routine skin closure for optimal skin cosmesis following the surgical procedure. |
Timeline
- Start date
- 2009-09-01
- Primary completion
- 2014-10-28
- Completion
- 2014-10-28
- First posted
- 2013-05-23
- Last updated
- 2022-09-28
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01860898. Inclusion in this directory is not an endorsement.