| Active Not Recruiting | Effect of PXS-4728A on Microglia Activation in Participants With Isolated Rapid Eye Movement Sleep Behaviour D REM Sleep Behavior Disorder | Phase 2 | 2023-11-08 |
| Completed | Study to Evaluate Safety, Pharmacokinetic and Pharmacodynamic Dose Escalation and Expansion Study of PXS-5505 Myelofibrosis | Phase 1 / Phase 2 | 2021-02-18 |
| Completed | A Two-part Pharmacokinetic Study of PXS-5382A in Healthy Adult Males Pharmacokinetics | Phase 1 | 2019-12-20 |
| Completed | A Safety and Efficacy Trial of Inhaled Mannitol in Adult Cystic Fibrosis Subjects Cystic Fibrosis | Phase 3 | 2014-09-01 |
| Completed | Crossover Trial Determining the Efficacy of Dry Powder Mannitol to Improve Lung Function in Subjects Aged 6-17 Cystic Fibrosis | Phase 2 | 2013-06-01 |
| Withdrawn | A Single Blind Study to Evaluate the Safety, Tolerability and Explore the Efficacy of 8.0 mg ASM8 Inhaled Dail Asthma | Phase 2 | 2011-11-01 |
| Completed | Efficacy of TPI ASM8 During a 14-Day Allergen Challenge Asthma | Phase 2 | 2010-11-01 |
| Completed | Inhaled Mannitol as a Mucoactive Therapy for Bronchiectasis Bronchiectasis | Phase 3 | 2009-11-01 |
| Withdrawn | Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Inhaled TPI 1100 in Healthy Volunteers Chronic Obstructive Pulmonary Disease | Phase 1 | 2009-04-01 |
| Completed | Efficacy and Safety of Four Escalating Dose Regimens of TPI ASM8 in Patients With Allergic Asthma Asthma | Phase 2 | 2009-04-01 |
| Completed | High Dose Inhaled Mannitol Study Bronchiectasis | Phase 1 / Phase 2 | 2009-01-01 |
| Completed | Cystic Fibrosis (CF) Flow Rates Study Cystic Fibrosis | — | 2009-01-01 |
| Completed | Pharmacokinetics of Inhaled Mannitol in Cystic Fibrosis Patients Cystic Fibrosis | Phase 1 | 2008-12-01 |
| Completed | Long Term Administration of Inhaled Mannitol in Cystic Fibrosis Cystic Fibrosis | Phase 3 | 2008-09-01 |
| Completed | A Pilot Study to Investigate Administration of Mannitol Via a Novel Dry Powder Inhaler Device Healthy, Bronchiectasis | Phase 1 / Phase 2 | 2008-08-01 |
| Completed | Inspiratory Flow and Volumes in Bronchiectatics Bronchiectasis | — | 2008-06-01 |
| Completed | Study to Evaluate the Safety and Efficacy TPI ASM8 in Subjects With Asthma Allergic Asthma | Phase 2 | 2008-01-01 |
| Completed | Inspiratory Flow Using the Osmohaler Asthma | — | 2007-11-01 |
| Completed | Safety, Tolerability and PD Activity of Inhaled TPI 1020 Versus Inhaled Budesonide in COPD Patients Copd Bronchitis | Phase 2 | 2007-11-01 |
| Completed | Long Term Administration of Inhaled Dry Powder Mannitol In Cystic Fibrosis - A Safety and Efficacy Study Cystic Fibrosis | Phase 3 | 2007-03-01 |
| Terminated | Safety and Efficacy of Two Dosages of Inhaled TPI ASM8 Compared to Placebo in Mild to Moderate Asthmatic Patie Asthma | Phase 2 | 2007-02-01 |
| Completed | A Pharmacokinetic and Bioavailability Study of Mannitol for Inhalation Using Normal Subjects Healthy Volunteers | Phase 1 | 2006-10-01 |
| Withdrawn | A Pilot Safety Study of Inhaled Dry Powder Mannitol in Acute Exacerbations of COPD COPD, Exacerbation | Phase 1 / Phase 2 | 2006-10-01 |
| Completed | Inhaled TPI-1020 Versus Inhaled Budesonide in Smokers With Mild Reversible Asthma Asthma | Phase 2 | 2006-05-01 |
| Completed | Safety and Efficacy of Bronchitol in Bronchiectasis Bronchiectasis | Phase 3 | 2006-03-01 |
| Completed | Multiple Dose ASM8 in Mild Asthmatics Asthma | Phase 1 / Phase 2 | 2005-12-01 |
| Completed | Comparison of Inhaled Mannitol and rhDNase in Children With Cystic Fibrosis Cystic Fibrosis | Phase 2 | 2005-11-01 |
| Completed | Ability of Aridol to Detect Bronchial Hyperresponsiveness in Suspected Asthmatics Asthma | Phase 3 | 2005-11-01 |
| Completed | Mannitol Dose Response Study in Cystic Fibrosis Cystic Fibrosis | Phase 2 | 2005-10-01 |
| Completed | Aridol Challenge as a Tool to Predict Treatment Response to Inhaled Corticosteroids in COPD Lung Diseases, Obstructive | Phase 2 | 2005-07-01 |
| Completed | A Phase 2 Study to Determine the Safety and Efficacy of Inhaled Dry Powder Mannitol in Cystic Fibrosis Cystic Fibrosis | Phase 2 | 2004-03-01 |