Clinical Trials Directory

Trials / Completed

CompletedNCT00264966

Multiple Dose ASM8 in Mild Asthmatics

A Double-blind, Placebo-controled, Crossover Study To Evaluate the Efficacy, Safety and Tolerability of Inhaled ASM8-003 in Subjects With Mild Allergic Asthma.

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
15 (planned)
Sponsor
Syntara · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Not accepted

Summary

To determine the safety and efficacy of multiple doses of ASM8 antisense oligonucleotides in asthmatics.

Detailed description

This is a double-blind, placebo-controlled, crossover trial to evaluate the safety, tolerability and efficacy of inhaled ASM8 for the treatment of allergen-induced asthma. Individuals with stable, mild to moderate allergic asthma by American Thoracic Society (ATS) criteria (1), with a history of episodic wheeze and shortness of breath, will be eligible for enrolment. The study is divided into 2 parts.

Conditions

Interventions

TypeNameDescription
DRUGASM8

Timeline

Start date
2005-12-01
Completion
2006-04-01
First posted
2005-12-13
Last updated
2012-12-03

Locations

3 sites across 1 country: Canada

Source: ClinicalTrials.gov record NCT00264966. Inclusion in this directory is not an endorsement.