Trials / Conditions / Li-Fraumeni Syndrome

Li-Fraumeni Syndrome

21 registered clinical trials studyying Li-Fraumeni Syndrome — 12 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Clinical Genetics Branch Eligibility Screening Survey NCT07005297	National Cancer Institute (NCI)	—
Completed	Exploring How to Adapt an Evidence-Based Mindful Self-Compassion Program for Young Adults With Li-Fraumeni Syn NCT07032922	National Cancer Institute (NCI)	—
Recruiting	Video Capsule Examination in Patients With Lynch Syndrome NCT06712095	Royal Marsden NHS Foundation Trust	N/A
Recruiting	Arsenic Trioxide Combined With Chemotherapy for the Treatment of p53-mutated Pediatric Cancer NCT06088030	Yang Li	Phase 2
Recruiting	Willingness to Participate in a Trial Comparing Standard Genetic Counseling Versus Personalized Genetic Counse NCT05126810	M.D. Anderson Cancer Center	—
Recruiting	Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients NCT06523582	Universidad Nacional Autonoma de Mexico	—
Unknown	Inherited Cancer Early Diagnosis (ICED) Study NCT06163365	Royal Marsden NHS Foundation Trust	—
Recruiting	Li-Fraumeni & TP53 (LiFT UP): Understanding and Progress NCT04541654	Dana-Farber Cancer Institute	—
Recruiting	Registry of Li Fraumeni and Li Fraumeni Like Syndromes NCT04982744	Istituto Ortopedico Rizzoli	—
Recruiting	Li-Fraumeni Syndrome/TP53 Biobank NCT04367246	Abramson Cancer Center at Penn Medicine	—
Completed	Phenotype and Prognosis of Patients With Breast Cancer and Pathogenic Variants of TP53 NCT04966923	Instituto do Cancer do Estado de São Paulo	—
Recruiting	Familial Investigations of Childhood Cancer Predisposition NCT03050268	St. Jude Children's Research Hospital	—
Enrolling By Invitation	Li-Fraumeni Syndrome Imaging Study NCT03176836	The Hospital for Sick Children	N/A
Completed	Biomarker Monitoring in TP53 Mutation Carriers NCT02289326	Scripps Health	—
Completed	A Pilot Study of Metformin in Patients With a Diagnosis of Li-Fraumeni Syndrome NCT01981525	National Cancer Institute (NCI)	Phase 1
Completed	Magnetic Resonance Imaging Screening in Li Fraumeni Syndrome NCT01737255	Institute of Cancer Research, United Kingdom	—
Active Not Recruiting	Screening With Whole Body MRI For Detection Of Primary Tumors In Children And Adults With Li-Fraumeni Syndrome NCT02950987	Dana-Farber Cancer Institute	N/A
Recruiting	Clinical and Genetic Studies of Li-Fraumeni Syndrome NCT01443468	National Cancer Institute (NCI)	—
Completed	LIFSCREEN : Evaluation of Whole Body MRI for Early Detection of Cancers in Subjects With P53 Mutation (Li-Frau NCT01464086	Gustave Roussy, Cancer Campus, Grand Paris	Phase 3
Recruiting	Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiova NCT01143454	National Heart, Lung, and Blood Institute (NHLBI)	—
Completed	Role of p53 Gene in Metabolism Regulation in Patients With Li-Fraumeni Syndrome NCT00406445	National Heart, Lung, and Blood Institute (NHLBI)	—