| Not Yet Recruiting | The AgRP and GH/IGF-1 Axis in Children NCT05645211 | Columbia University | — |
| Not Yet Recruiting | Evaluation of (Cardio)Metabolic and Auxological Outcomes of GHD Patients Under rhGH or LAGH With Stratificatio NCT07173036 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Not Yet Recruiting | BELux Children OutcoME During A(@)Dulthood With GHD NCT06694506 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Enrolling By Invitation | A Study to Follow Paediatric Participants With Growth Hormone Deficiency Treated With Somapacitan for Long Ter NCT06709040 | Novo Nordisk A/S | — |
| Not Yet Recruiting | Growing up With the Young Endocrine Support System (YESS!) NCT04252001 | dr. Laura C. G. de Graaff-Herder | N/A |
| Recruiting | Evaluation of the Propensity of Patients Under rhGH to Envision a Modification of Their Treatment Regimen Towa NCT06542809 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Enrolling By Invitation | A Long-Term Safety Trial of LUM-201 in Children With Idiopathic Growth Hormone Deficiency Who Have Previously NCT05796440 | Lumos Pharma | Phase 2 |
| Completed | Biological Age in Children With GH Deficiency Undergoing Hormone Replacement Therapy NCT06294860 | Istituto Auxologico Italiano | — |
| Recruiting | Effects of GH and Lirglutide on AgRP NCT05681299 | Columbia University | Phase 4 |
| Recruiting | Use of miRNAs in Growth Hormone Deficiency (GHD) NCT06455956 | University of Parma | — |
| Recruiting | A US Non-interventional, Effectiveness and Safety Study of Patients Treated With SKYTROFA NCT05820672 | Ascendis Pharma Endocrinology Division A/S | — |
| Recruiting | A Post-Authorisation Safety Study (PASS) of Patients Treated With Lonapegsomatropin NCT05775523 | Ascendis Pharma Endocrinology Division A/S | — |
| Unknown | Growth Hormone Deficiency in Mild Traumatic Brain Injury NCT05660356 | University of Calgary | EARLY_Phase 1 |
| Unknown | Adaption and Testing of the Quality of Life in Short Stature Youth (QoLISSY) Questionnaire for Parents With Ch NCT05603936 | Universitätsklinikum Hamburg-Eppendorf | — |
| Completed | Phase 2 Study of LUM-201 in Children Who Have Previously Completed the LUM-201-01 Trial (OraGrowtH213) NCT05250063 | Lumos Pharma | Phase 2 |
| Completed | Isolated Growth Hormone Deficiency and Amennorrhea NCT05448924 | Universitas Padjadjaran | — |
| Completed | A Research Study of How Well Macimorelin Works to Find Out if Children Have a Lack of Growth Hormone and How S NCT04786873 | AEterna Zentaris | Phase 3 |
| Completed | Assessment of Adherence, Quality of Life, Clinical Response and Safety of Daily and Long-Acting Growth Hormone NCT04938466 | University of Minnesota | — |
| Active Not Recruiting | PK and PD Study of LUM-201 in Children With Idiopathic Growth Hormone Deficiency: (OraGrowtH212) NCT04806854 | Lumos Pharma | Phase 2 |
| Recruiting | Long-term Safety and Effectiveness of Growtropin®-II Treatment in Children With Short Stature NCT04798690 | Dong-A ST Co., Ltd. | — |
| Completed | Phase 2 Study of LUM-201 in Children With Growth Hormone Deficiency (OraGrowtH210 Trial) NCT04614337 | Lumos Pharma | Phase 2 |
| Completed | A Trial to Compare the Efficacy and Safety of Once-weekly Lonapegsomatropin With Placebo and a Daily Somatropi NCT04615273 | Ascendis Pharma Endocrinology Division A/S | Phase 3 |
| Withdrawn | Fluids Administration During Combined Clonidine-Arginine Growth Hormone Stimulation Test NCT04465565 | Rabin Medical Center | N/A |
| Unknown | Safety, Tolerability and Efficacy of TransCon hGH Weekly Versus Daily hGH in Chinese Pediatric Growth Hormone NCT04326374 | Visen Pharmaceuticals (Shanghai) Co., Ltd. | Phase 3 |
| Recruiting | Growth Hormone Replacement Therapy for Retried Professional Football Players NCT04121780 | Center for Neurological Studies | Phase 2 |
| Completed | Skeletal Muscle Effects of GH in Boys NCT04020913 | Nemours Children's Clinic | — |
| Completed | Adipose Tissue and Serum Inflammation in GH Deficiency NCT03500913 | Columbia University | — |
| Unknown | Effects of Growth Hormone and IGF-1 on Anabolic Signals and Stem Cell Recruitment in Human Skeletal Muscle NCT03878992 | University of Aarhus | N/A |
| Unknown | Gene Expression in Monocytes of Growth Hormone Deficient Children NCT04352712 | University of Salerno | — |
| Completed | Impact of GH Measurements on GHD Diagnosis NCT04508673 | University Hospital, Montpellier | — |
| Completed | A Study to Compare the Uptake Into the Blood of Two Strengths of Somapacitan After Injection Under the Skin in NCT03905850 | Novo Nordisk A/S | Phase 1 |
| Unknown | Treatment of GHD Associated With CHF NCT03775993 | Federico II University | Phase 3 |
| Completed | Patient Perception of Treatment Burden in Weekly Versus Daily Growth Hormone Injections in Children With GHD NCT03831880 | Pfizer | Phase 3 |
| Completed | Safety and Efficacy of Y-shape Pegylated Somatropin in Growth Hormone Deficiency Children NCT04513171 | Xiamen Amoytop Biotech Co., Ltd. | Phase 2 / Phase 3 |
| Completed | Body Composition and Adipose Tissue in HIV NCT03226821 | Columbia University | Phase 4 |
| Completed | Development and Validation of a Self-assessment System Based on a Mobile App to Manage Adult Growth Hormone De NCT03525587 | Azienda Ospedaliero-Universitaria di Modena | N/A |
| Completed | Safety and Efficacy Study of MOD-4023 to Treat Children With Growth Hormone Deficiency NCT03874013 | OPKO Health, Inc. | Phase 3 |
| Unknown | Exploring Interactions Between Growth Hormone and the Microbiome NCT03327207 | Rambam Health Care Campus | — |
| Completed | Adipose Tissue and Circulating Markers of Inflammation in GH Deficiency and Changes With GH Therapy NCT03225755 | Columbia University | — |
| Terminated | A Long-Term Safety Study of Somavaratan in Japanese Children With Growth Hormone Deficiency NCT03145831 | Versartis Inc. | Phase 3 |
| Completed | Dynamic Hormone Diagnostics in Endocrine Disease NCT02934399 | Haukeland University Hospital | — |
| Completed | Evaluation of the Ease of Use, Preference, and Safety of EutropinPen Inj. NCT03015909 | LG Life Sciences | Phase 4 |
| Completed | Dose Finding Study of GX-H9 in Paeditaric Patients With Growth Hormone Deficiency NCT03309891 | Genexine, Inc. | Phase 2 |
| Terminated | Study of TV-1106 in Growth Hormone-Deficient Adults NCT02410343 | Teva Branded Pharmaceutical Products R&D, Inc. | Phase 3 |
| Terminated | Study to Assess Safety and Tolerability in Adults With Growth Hormone-Deficiency (GHD) NCT02410356 | Teva Branded Pharmaceutical Products R&D, Inc. | Phase 3 |
| Completed | A Post-Marketing Study of the Immunogenicity of Somatropin (Ribosomal Deoxyribo Nucleic Acid [rDNA] Origin) In NCT02311894 | Genentech, Inc. | Phase 4 |
| Completed | Pharmacokinetics and Pharmacodynamics of Long Acting Human Growth Hormone (hGH) Product (MOD-4023) in Healthy NCT02418767 | OPKO Health, Inc. | Phase 1 |
| Unknown | The Impact of the Use of Recombinant Human Growth Hormone on ADHD Characteristics in Children and Adolescents NCT02973061 | Assaf-Harofeh Medical Center | — |
| Unknown | Pegylated Somatropin (PEG Somatropin) in the Treatment of Children With Growth Hormone Deficiency NCT02976675 | Changchun GeneScience Pharmaceutical Co., Ltd. | Phase 4 |
| Unknown | Pegylated Somatropin (PEG Somatropin) in the Treatment of Children With Growth Hormone Deficiency NCT03249480 | Changchun GeneScience Pharmaceutical Co., Ltd. | Phase 4 |
| Unknown | Phase IV Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency Children ( NCT02380235 | Changchun GeneScience Pharmaceutical Co., Ltd. | Phase 4 |
| Unknown | Clinical Study of Pegylated Somatropin to Treat Children Growth Hormone Deficiency NCT02908958 | Changchun GeneScience Pharmaceutical Co., Ltd. | Phase 4 |
| Withdrawn | Effects of Growth Hormone (GH) Deficiency and Growth Hormone Replacement on Serum Fibroblast Growth Factor 21 NCT02243852 | University of Liverpool | — |
| Terminated | Evaluation of the Adherence and the Patient Acceptability of Zomacton® Treatment With the Zomajet® Vision X De NCT02018172 | Ferring Pharmaceuticals | — |
| Completed | Growth and Asymmetric diMethylArginine NCT03422081 | University Hospital, Lille | — |
| Terminated | A Phase 2, Safety and Dose-Finding Study in Treatment-Naive, Pre-Pubertal, Growth Hormone-Deficient Children NCT02092077 | Teva Pharmaceutical Industries, Ltd. | Phase 2 |
| Completed | Observational Longitudinal Study in Children Affected by Idiopathic Growth Hormone Deficiency (GHD) NCT02507245 | Stefania La Grutta, MD | — |
| Completed | Evalutation of Insulin Sensitivity Through Hyperinsulinemic Clamp in Children With GH Deficiency NCT03525171 | University of Palermo | N/A |
| Completed | A Prospective Non-Interventional Study Protocol With Primary Data Collection - Assessment Of The Long Term Tre NCT01947894 | Pfizer | — |
| Completed | GH and Cardiovascular Risk Factors NCT01877512 | Amsterdam UMC, location VUmc | Phase 4 |
| Completed | Safety, Tolerability and Efficacy of Weekly TV-1106 in Adults With Growth Hormone Deficiency NCT01811576 | Teva Branded Pharmaceutical Products R&D, Inc. | Phase 2 |
| Completed | Phase 1 Safety Study of ALRN-5281 in Healthy Subjects NCT01775358 | Aileron Therapeutics, Inc. | Phase 1 |
| Withdrawn | Surveillance of Treatment of Children With Growth Hormone Deficiency With Zomacton® NCT01731028 | Ferring Pharmaceuticals | — |
| Recruiting | Long-term Safety and Effectiveness of Growth Hormone With GHD, TS, CRF, SGA , ISS and PWS in Children NCT01604395 | LG Chem | — |
| Completed | Safety, Pharmacokinetics and Pharmacodynamics Study of HL-032 in Healthy Male Volunteers NCT01440686 | HanAll BioPharma Co., Ltd. | Phase 1 |
| Completed | The Effect of Dietary Fat Load and Physical Exercise on the Flexibility and Partitioning of Ectopic Lipids. NCT01467193 | Insel Gruppe AG, University Hospital Bern | — |
| Terminated | Free Fatty Acids, Body Weight, and Growth Hormones Secretion in Children NCT01237041 | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | Phase 1 / Phase 2 |
| Completed | Effects of Growth Hormone Supplementation to Adults With Growth Hormone Deficient on Metabolism and Adipose Ti NCT01616095 | Slovak Academy of Sciences | — |
| Completed | VRS-317 in Adult Subjects With Growth Hormone Deficiency NCT01359488 | Versartis Inc. | Phase 1 |
| Terminated | A Study to Evaluate Growth in Participants Treated With Somatropin (Nutropin) Using NuSpin Device NCT01243892 | Genentech, Inc. | — |
| Completed | Diurnal Variation of Exogenous Peptides (GH Puls/Jurgita I) NCT01090778 | Aarhus University Hospital | Phase 2 |
| Completed | Cross Over Convenience And Preference Study Of New Mark VII Compared To Genotropin Pen In Pediatric And Adult NCT01112865 | Pfizer | Phase 3 |
| Completed | Growth Hormone Deficiency in Chronic Heart Failure: an Observational Study NCT00511927 | Federico II University | — |
| Completed | Reference Values for Body Composition Parameters and IGF-I in the Adult NordiNet® International Outcome Study NCT01120977 | University of Aarhus | — |
| Completed | Crossover Study to Assess the Safety and Pharmacokinetic of Pegylated Somatropin(PEG Somatropin) in GHD Childr NCT01613573 | Changchun GeneScience Pharmaceutical Co., Ltd. | Phase 1 |
| Completed | A Study of Zomacton in Children With Growth Hormone Deficiency NCT00884000 | Ferring Pharmaceuticals | Phase 3 |
| Completed | Safety and Efficacy of SR-hGH (Sustained-release Human Growth Hormone, Declage Inj.) NCT01605331 | LG Life Sciences | Phase 4 |
| Completed | Peripheral Metabolic Effects of Somatostatin NCT01062529 | University of Aarhus | N/A |
| Completed | Genotropin Study Assessing Use of Injection Pen NCT00965484 | Pfizer | Phase 3 |
| Completed | Comparison of a Needle-free Injection Method With a Needle-syringe Injection Method NCT00990340 | Teva Branded Pharmaceutical Products R&D, Inc. | Phase 4 |
| Unknown | Study of Weekly ALTU-238 Compared With Daily Nutropin AQ in Prepubertal Children With Growth Hormone Deficienc NCT00837863 | Altus Pharmaceuticals | Phase 2 |
| Completed | Is There a Sensibility Increased in the Growth Hormone at Child With Prader-Willi Syndrome? NCT01298180 | University Hospital, Toulouse | Phase 4 |
| Completed | Effectiveness of Growth Hormone Releasing Hormone in Reducing Abdominal Fat in People Who Are Obese NCT00675506 | Massachusetts General Hospital | Phase 2 |
| Completed | r-hGH Liquid Multidose Versus Freeze-dried Multidose Bioequivalence Trial NCT01034735 | EMD Serono | Phase 1 |
| Completed | Safety, Tolerability and PK/PD Study in Young Adult Patients With Childhood Onset Growth Hormone Deficiency (G NCT00778518 | Ambrx, Inc. | Phase 2 |
| Completed | Cardiovascular Risk in Growth Hormone Deficient Young Adult Males After Completing Growth Hormone Therapy NCT00711061 | Children's Mercy Hospital Kansas City | — |
| Terminated | Efficacy of Somatropin in Adult Patients With Isolated Growth Hormone Deficiency NCT00630487 | Pfizer | Phase 3 |
| Completed | Insulin Sensitivity and Substrate Metabolism Before and After Treatment in Patients With Growth Hormone Defici NCT00646815 | University of Aarhus | N/A |
| Terminated | Treatment Of Adult Growth Hormone Deficiency After Traumatic Brain Injury NCT00555009 | Pfizer | Phase 4 |
| Terminated | Assessment of Cardiovascular Risk Markers in Growth Hormone Deficient Patients With Nonsecreting Pituitary Ade NCT00646308 | Columbia University | — |
| Completed | Easypod United States User Trial NCT00689260 | EMD Serono | Phase 4 |
| Terminated | Differential Effects of rhGH vs. rhIGF-1 on Cardiovascular Risk Factors NCT00684957 | Columbia University | Phase 1 / Phase 2 |
| Completed | Online Surveillance of Treatment of Children With Growth Hormone Deficiency With ZOMACTON NCT01365351 | Ferring Pharmaceuticals | — |
| Withdrawn | Inter-Assay Growth Hormone and IGF-I Variability NCT00638287 | Cedars-Sinai Medical Center | — |
| Completed | Sexually Dimorphic Effects of GHRH in Adult Growth Hormone Testing NCT00324064 | Children's Mercy Hospital Kansas City | N/A |
| Completed | The Effects of Growth Hormone (GH) on Lipid Depots NCT00491582 | Insel Gruppe AG, University Hospital Bern | N/A |
| Completed | Cardiac and Skeletal Muscle Energy Metabolism in Abnormal Growth Hormone States NCT00461240 | Barts & The London NHS Trust | — |
| Completed | Evaluation of Convenience and Compliance of the Easypod™ Electronic Self-injector NCT00738205 | Merck KGaA, Darmstadt, Germany | — |
| Completed | A Multi-Dose Study to Assess Tolerability, Safety and Pharmacology of hGH-ViaDerm™ System in Adults With GH-De NCT00455260 | Teva Neuroscience, Inc. | Phase 1 |
| Completed | Phase III Clinical Study of Pegylated Somatropin (PEG Somatropin) to Treat Growth Hormone Deficiency Children NCT01495468 | Changchun GeneScience Pharmaceutical Co., Ltd. | Phase 3 |
| Terminated | Adult Growth Hormone Deficiency and Cardiovascular Risk NCT00720902 | Columbia University | Phase 4 |
| Completed | Long-Term Efficacy and Safety of Growth Hormone Replacement Therapy in Chronic Heart Failure NCT01576861 | Federico II University | Phase 2 |
| Terminated | A Study To Evaluate The Dose Response And Safety Of PHA-794428 In Adults With Growth Hormone Deficiency NCT00308464 | Pfizer | Phase 2 |
| Completed | Efficiency and Safety Study of Pegylated Somatropin to Treat Growth Hormone Deficiency Children NCT01342146 | Changchun GeneScience Pharmaceutical Co., Ltd. | Phase 2 |
| Terminated | A Single Dose Study to Evaluate the PK-PD Response and Safety of PHA-794428 in Children With Growth Hormone De NCT00314938 | Pfizer | Phase 2 |
| Completed | Low Dose Growth Hormone (GH) on Insulin Sensitivity and Cortisol Production Rates NCT00517062 | Oregon Health and Science University | EARLY_Phase 1 |
| Completed | Cardiac Function and Morphology Evaluated by Magnetic Resonance Imaging in Growth Hormone Deficiency and Acrom NCT00970463 | Herlev Hospital | — |
| Unknown | 304-C03/L3301n: Effects of Growth Hormone on Glucose and Protein Metabolism in Children With Growth Hormone De NCT00362063 | Baylor College of Medicine | N/A |
| Completed | National Cooperative Growth Study in CKD NCT00616278 | University of California, Davis | — |
| Completed | The IGFBP-3 Stimulation Test: A New Tool for the Diagnosis of Growth Hormone Deficiency in Children. NCT00235599 | University of Massachusetts, Worcester | — |
| Completed | Consequence of Lifetime Isolated Growth Hormone Deficiency NCT00149708 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | N/A |
| Terminated | Growth Hormone's Effect on the Cardiovascular System NCT00397319 | Vanderbilt University | — |
| Completed | Predictive Markers in Growth Hormone Deficiency (GHD) and Turner Syndrome (TS) Children Treated With SAIZEN® NCT00256126 | Merck KGaA, Darmstadt, Germany | Phase 4 |
| Completed | Adipocyte Function and Somtropin Deficiency NCT01351818 | Ferring Pharmaceuticals | — |
| Unknown | Growth Hormone Treatment of Young Growth Hormone-Deficient Adults NCT00187993 | University Hospital, Angers | — |
| Completed | A Study to Optimize Growth Hormone Dosing in Children With Chronic Kidney Disease by Measuring IGF-1 Levels in NCT00212758 | Oregon Health and Science University | Phase 4 |
| Completed | Growth Hormone and Endothelial Function in Children NCT00373386 | Ohio State University | Phase 4 |
| Completed | Evolution Of Growth Rate In Children With Growth Retardation Due to Glucocorticosteroid Therapy And Treated By NCT00163189 | Pfizer | Phase 3 |
| Completed | Endocrine Dysfunction and Growth Hormone Deficiency in Children With Optic Nerve Hypoplasia NCT00140413 | Children's Hospital Los Angeles | Phase 4 |
| Completed | Growth Hormone Deficiency in Chronic Heart Failure: A Preliminary Trial NCT00591760 | Federico II University | Phase 2 |
| Completed | The Effects of TZD on Fat Metabolism and Insulin Sensitivity in GH-Replaced GHD Patients NCT00459940 | University of Aarhus | N/A |
| Completed | Safety Study of Syntropin (Human Growth Hormone) for the Treatment of Growth Hormone Deficiency NCT00489294 | Phage Pharmaceuticals, Inc. | Phase 1 |
| Completed | Effects of Growth Hormone Administration on Cardiovascular Risk in Cured Acromegalics With Growth Hormone Defi NCT00182091 | Massachusetts General Hospital | N/A |
| Terminated | Constructing an Insulin-Like Growth Factor-based Prediction Model NCT00263445 | University of California, Los Angeles | — |
| Completed | Growth Hormone as Add-on Treatment in Severe Fibromyalgia With Low IGF-1 Serum Levels (56 Characters) NCT00497562 | Centro Medico Teknon | Phase 2 |
| Completed | Efficacy and Safety of a High Dosage Compared to the Label Dosage of Somatropin in Early Pubertal Stage Childr NCT00191165 | Eli Lilly and Company | Phase 3 |
| Completed | Testosterone and Growth Hormone for Bone Loss in Men NCT00080483 | University of Pennsylvania | Phase 2 |
| Completed | Comparative Validation of the Growth Hormone Releasing Hormone and Arginine Test for the Diagnosis of Adult Gr NCT01060488 | Merck KGaA, Darmstadt, Germany | Phase 3 |
| Completed | Molecular Basis of the Growth Axis in Short Stature NCT00453245 | HaEmek Medical Center, Israel | — |
| Completed | Anterior Pituitary Hormone Replacement in Traumatic Brain Injury NCT00957671 | The University of Texas Medical Branch, Galveston | Phase 4 |
| Completed | Growth Hormone and Glucose Metabolism NCT00929799 | Charite University, Berlin, Germany | Phase 4 |
| Completed | Evaluation of Efficacy and Safety of Recombinant Somatroipn in Patients With Growth Hormone Deficiency NCT02693522 | Daewoong Pharmaceutical Co. LTD. | Phase 3 |
| Completed | A Multicentre, Randomised, Open-label, Controlled Study to Evaluate the Effects of Saizen® on Cardiac Function NCT01157793 | Merck KGaA, Darmstadt, Germany | Phase 4 |
| Completed | Practicability and Acceptability of Stylomax® in Children NCT00476385 | Sanofi | Phase 3 |
| Completed | Sustained Release Formulation of Somatropin (rDNA Origin)for Injection NCT00600808 | BioPartners GmbH | Phase 2 / Phase 3 |
| Completed | Transition Study: Growth Hormone Therapy In Partial Growth Hormone Deficient Adolescents NCT00156143 | Pfizer | Phase 3 |
| Completed | Growth Hormone Administration and Its Effects on Cardiovascular Risk Factors in Growth Hormone Deficient Women NCT00136032 | Massachusetts General Hospital | N/A |
| Completed | Diagnosing Adult Growth Hormone Deficiency NCT03018886 | Helsinki University Central Hospital | N/A |
| Completed | IGF1 Generation Test NCT00145457 | Pfizer | Phase 4 |
| Completed | Growth Hormone and Chromosome 18q- and Abnormal Growth NCT00134420 | The University of Texas Health Science Center at San Antonio | Phase 3 |
| Completed | Low and Conventional Dose of Somatropin in Growth Hormone Deficient Adult Patients NCT00570011 | Eli Lilly and Company | Phase 3 |
| Completed | Randomized Study of Growth Hormone on Bone Mineral Density in Patients With Adult Onset Growth Hormone Deficie NCT00006394 | National Center for Research Resources (NCRR) | N/A |
| Completed | Treatment With Recombinant Human Growth Hormone Genotonorm (Registered) In Children With Short Stature Seconda NCT00174278 | Pfizer | Phase 3 |
| Completed | Effect of 5 Years of GH Replacement on Atherosclerosis NCT00462475 | Federico II University | — |
| Completed | Study of Pituitary Size and Function in Familial Dwarfism of Sindh NCT00004365 | National Center for Research Resources (NCRR) | — |
| Recruiting | Chromosome 18 Clinical Research Center NCT00227253 | The University of Texas Health Science Center at San Antonio | — |