| Terminated | Long-term Safety and Tolerability of Atacicept (Long-term Follow-Up of Participant Who Participated in ADDRESS Lupus Erythematosus, Systemic | Phase 2 | 2014-07-29 |
| Terminated | Sym004 in Subjects With Stage IV Non-small Cell Lung Cancer Carcinoma, Non-Small-Cell Lung | Phase 1 | 2014-07-01 |
| Terminated | RESOunD: REbif Satisfaction On Discontinuing Oral Dimethyl Fumarate Multiple Sclerosis | Phase 4 | 2014-06-01 |
| Terminated | Tecemotide Following Concurrent Chemo-radiotherapy for Non-small Cell Lung Cancer Carcinoma, Non-Small-Cell Lung | Phase 3 | 2014-03-01 |
| Completed | Rebif® Rebidose® Versus Rebiject II® Ease-of-Use Multiple Sclerosis, Relapsing-Remitting | Phase 4 | 2014-03-01 |
| Terminated | MSB0010445 and Stereotactic Body Radiation Therapy in Advanced Melanoma Melanoma | Phase 2 | 2014-01-01 |
| Completed | First-in-Human Dose Escalation Trial in Subjects With Advanced Malignancies Solid Tumor | Phase 1 | 2013-12-13 |
| Completed | Efficacy and Safety of Atacicept in Systemic Lupus Erythematosus Lupus Erythematosus, Systemic | Phase 2 | 2013-12-01 |
| Completed | Relative Bioavailability of Pimasertib in Cancer Patients Neoplasms | Phase 1 | 2013-11-30 |
| Terminated | Efficacy, Safety, and Tolerability of Plovamer Acetate (Pathway 1) Relapsing Remitting Multiple Sclerosis | Phase 2 | 2013-10-01 |
| Completed | Trial of Pimasertib With SAR245409 or Placebo in Ovarian Cancer Ovarian Cancer | Phase 2 | 2013-09-30 |
| Terminated | Adherence Trial With MS LifeLines ® Services Multiple Sclerosis, Relapsing-Remitting | — | 2013-07-01 |
| Terminated | A Multicenter Trial of Sprifermin (AS902330 [Recombinant Human Fibroblast Growth Factor-18]) or Placebo After Cartilage Injury of Knee | Phase 2 | 2013-04-01 |
| Completed | Phase II Trial of Pimasertib Versus Dacarbazine in N-Ras Mutated Cutaneous Melanoma N-Ras Mutated Locally Advanced or Metastasis Malignant Cutaneous Melanoma | Phase 2 | 2012-12-05 |
| Withdrawn | Atacicept Demonstrating Dose RESponSe Systemic Lupus Erythematosus | Phase 2 | 2012-02-01 |
| Completed | Tecemotide (L-BLP25) in Prostate Cancer Prostate Cancer | Phase 2 | 2011-10-24 |
| Terminated | MSC2015103B in Solid Tumors Advanced Solid Tumor | Phase 1 | 2011-09-01 |
| Terminated | Atacicept in Lupus Nephritis Patients Taking Stable Regimen of Mycophenolate Mofetil Lupus Nephritis | Phase 1 | 2011-06-01 |
| Terminated | Combination Trial of Pimasertib (MSC1936369B) With Temsirolimus Advanced Solid Tumor | Phase 1 | 2011-05-27 |
| Completed | Trial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid Tumors Locally Advanced Solid Tumor, Metastatic Solid Tumor, Breast Cancer | Phase 1 | 2011-05-01 |
| Completed | EMD 525797 in Subjects With Asymptomatic or Mildly Symptomatic Metastatic Castrate-resistant Prostate Cancer Prostate Cancer Metastatic | Phase 2 | 2011-04-01 |
| Terminated | Saizen® Solution for Injection Adult Growth Hormone Deficiency (GHD) Immunogenicity Study Growth Hormone Deficiency (GHD) | Phase 3 | 2010-10-01 |
| Terminated | Phase 2 Extension Trial in Patients With Relapsing-Remitting Multiple Sclerosis (RRMS) Multiple Sclerosis | Phase 2 | 2010-10-01 |
| Completed | Retrospective Cohort Study of Rebif® Use in Pediatric Multiple Sclerosis (MS) Subjects (REPLAY) Multiple Sclerosis | — | 2010-07-01 |
| Completed | Rebif Advanced Magnetic Resonance Imaging (MRI) and Immunology Pilot Trial Multiple Sclerosis | Phase 4 | 2010-06-30 |
| Terminated | First-in-Man, Dose-escalation Trial of c-Met Kinase Inhibitor EMD 1204831 in Subjects With Advanced Solid Tumo Solid Tumors | Phase 1 | 2010-04-01 |
| Terminated | MEK Inhibitor MSC1936369B Plus FOLFIRI in Second Line K-Ras Mutated Metastatic Colorectal Cancer (mCRC) Metastatic Colorectal Cancer | Phase 1 / Phase 2 | 2010-03-01 |
| Completed | The REbif® vs Glatiramer Acetate in Relapsing Multiple Sclerosis Pharmacogenetics Trial Relapsing Multiple Sclerosis | Phase 4 | 2010-02-01 |
| Completed | A Multicenter, Open-label, RebiSmart™ Autoinjector Ease of Use Study Multiple Sclerosis | Phase 3 | 2010-01-01 |
| Completed | EMD 1201081 in Combination With Cetuximab in Second-Line Cetuximab-Naïve Subjects With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck Cancer | Phase 2 | 2009-12-01 |
| Completed | Trial of Gemcitabine With or Without MSC1936369B in Pancreatic Cancer Pancreatic Adenocarcinoma | Phase 1 / Phase 2 | 2009-11-30 |
| Completed | Prospective Observational Long-term Safety Registry of Multiple Sclerosis Participants Who Have Participated i Multiple Sclerosis | — | 2009-11-30 |
| Completed | First-in-Man, Dose-escalation Trial of C-met Kinase Inhibitor MSC2156119J in Subjects With Advanced Solid Tumo Patients With Solid Tumors, Either Refractory to Standard Therapy or for Which no Effective Standard Therapy is Available | Phase 1 | 2009-11-30 |
| Completed | The Multicenter, Open-label, Single-use Autoinjector Convenience Study Multiple Sclerosis | Phase 3 | 2009-10-01 |
| Terminated | Trial of Pimasertib in Hematological Malignancies Leukemia, Myeloid, Acute, Hematologic Neoplasms | Phase 2 | 2009-09-30 |
| Terminated | STRIDE - STimulating Immune Response In aDvanced brEast Cancer Breast Cancer | Phase 3 | 2009-09-01 |
| Completed | Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Un Glioblastoma | Phase 2 | 2009-03-01 |
| Terminated | Atacicept in Multiple Sclerosis Extension Study, Phase II Relapsing Multiple Sclerosis | Phase 2 | 2009-03-01 |
| Terminated | Study of FOLFIRI Plus Cetuximab Plus IMO-2055 in Patients With Colorectal Cancer Colorectal Cancer | Phase 1 | 2009-01-01 |
| Completed | Cilengitide, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma and Me Glioblastoma | Phase 3 | 2008-09-01 |
| Completed | 12-week Study to Evaluate RebiSmart™ Suitability for Self Injection in Relapsing Multiple Sclerosis. Multiple Sclerosis | Phase 3 | 2008-07-01 |
| Completed | r-hGH Liquid Multidose Versus Freeze-dried Multidose Bioequivalence Trial Growth Failure, Growth Hormone Deficiency | Phase 1 | 2008-07-01 |
| Terminated | Atacicept in Subjects With Optic Neuritis Optic Neuritis | Phase 2 | 2008-06-01 |
| Completed | Oocyte Cryopreservation Registry (HOPE Registry) Oocyte Cryopreservation | — | 2008-06-01 |
| Terminated | A Phase 2 Study of Atacicept in Subjects With Relapsing Multiple Sclerosis (ATAMS) Relapsing Multiple Sclerosis | Phase 2 | 2008-04-01 |
| Completed | Easypod United States User Trial Growth Hormone Deficiency | Phase 4 | 2008-03-01 |
| Completed | Atacicept Phase 2/3 in Generalized Systemic Lupus Erythematosus (APRIL-SLE) Lupus Erythematosus, Systemic | Phase 2 / Phase 3 | 2008-01-01 |
| Terminated | The Efficacy and Safety of Atacicept in Combination With Mycophenolate Mofetil Used to Treat Lupus Nephritis Lupus Nephritis | Phase 2 / Phase 3 | 2007-12-01 |
| Completed | A Multi-center, Multi-regional Observational Study to Test the Responsiveness of the Validated MusiQoL (Multip Multiple Sclerosis | — | 2007-11-01 |
| Completed | Safety of Adding IMO-2055 to Erlotinib + Bevacizumab in 2nd Line Treatment for Patients With NSCLC Non-Small Cell Lung Cancer | Phase 1 | 2007-11-01 |
| Completed | Atacicept in Anti-Tumor Necrosis Factor Alpha-naïve Subjects With Rheumatoid Arthritis (AUGUST II) Rheumatoid Arthritis | Phase 2 | 2007-09-01 |
| Completed | Rebif New Formulation (RNF) Quality of Life (QOL) Study Relapsing Multiple Sclerosis | Phase 3 | 2007-04-01 |
| Completed | Cancer Vaccine Study for Unresectable Stage III Non-small Cell Lung Cancer (START) Non-small Cell Lung Cancer | Phase 3 | 2007-01-01 |
| Withdrawn | Determine if Either of 2 Doses of Study Drug Given With a Low-dose of Cyclophosphamide After a Complete or Par Ovarian Cancer | Phase 2 | 2006-12-31 |
| Completed | A Phase 2 Dose-finding Study of Atacicept in Subjects With Rheumatoid Arthritis (AUGUST I) Rheumatoid Arthritis | Phase 2 | 2006-12-01 |
| Completed | RNF and Betaseron® Tolerability Study Relapsing Remitting Multiple Sclerosis (RRMS) | Phase 3 | 2006-12-01 |
| Terminated | A Phase I, Dose-escalation Study of AS703569 Given Orally to Subjects With Haematological Malignancies Haematological Malignancies | Phase 1 | 2006-12-01 |
| Completed | AS703569 Phase I in Patients With Solid Tumours Solid Tumors | Phase 1 | 2006-08-01 |
| Terminated | Luveris® (Lutropin Alfa for Injection) in Women With Hypogonadotropic Hypogonadism (Luteinizing Hormone [LH] L Hypogonadotropic Hypogonadism | Phase 4 | 2006-03-01 |
| Completed | ATS-1 Needle Free Injection Device Study-a Device for Administering r-hGH (Saizen) to Treat Growth Hormone Def Healthy | Phase 1 | 2005-09-01 |
| Completed | Effects of Matuzumab in Combination With Pemetrexed for the Treatment of Advanced Lung Cancer Lung Cancer, Non Small Cell Lung Carcinoma | Phase 2 | 2005-05-31 |
| Completed | EMD 273066 in Patients With Recurrent EpCAM Positive Ovarian, Prostate, Colorectal or Non-small Cell Lung Canc Ovarian Cancer, Colorectal Cancer, Carcinoma, Non-small-cell Lung | Phase 1 | 2005-05-01 |
| Completed | A Safety and Efficacy Study of Oral Cladribine in Subjects With Relapsing-remitting Multiple Sclerosis (RRMS) Multiple Sclerosis, Relapsing-Remitting | Phase 3 | 2005-04-01 |
| Completed | Comparison of Anastrozole Verses Clomiphene Citrate in Stimulating Follicular Growth and Ovulation in Infertil Anovulation | Phase 2 | 2005-03-10 |
| Completed | Safety and Efficacy Study of Serostim® Human Immunodeficiency Virus-Associated Adipose Redistribution Syndrome Human Immunodeficiency Virus-Associated Adipose Redistribution Syndrome | Phase 3 | 2005-02-01 |
| Completed | Cool.Click™ Adolescent Transition Study: Study of Saizen® in Subjects With Childhood-onset Growth Hormone Defi Childhood-onset Growth Hormone Deficiency, Pituitary Dwarfism | Phase 3 | 2005-01-01 |
| Completed | Rebif New Formulation (RNF) in Relapsing Forms of Multiple Sclerosis Multiple Sclerosis | Phase 3 | 2005-01-01 |
| Withdrawn | Implementation Study of Treatment Optimization Recommendations on Relapsing-Remitting Multiple Sclerosis (RR M Relapsing-Remitting Multiple Sclerosis | Phase 4 | 2004-11-01 |
| Completed | Cilengitide (EMD 121974) for Recurrent Glioblastoma Multiforme (Brain Tumor) Glioblastoma Multiforme | Phase 2 | 2004-10-13 |
| Completed | Sarizotan in Participants With Parkinson's Disease Suffering From Treatment Associated Dyskinesia Parkinson's Disease, Dyskinesia | Phase 3 | 2004-09-30 |
| Completed | Sarizotan HC1 in Patients With Parkinson's Disease Suffering From Treatment-associated Dyskinesia Parkinson's Disease, Dyskinesia | Phase 3 | 2004-09-30 |
| Completed | A Prospective Study to Evaluate the Addition of Subcutaneous Recombinant Human-Luteinizing Hormone With Recomb Infertility, Ovarian Stimulation | Phase 3 | 2004-09-01 |
| Terminated | Onercept in the Treatment and Re-Treatment of Subjects With Moderate to Severe Plaque Psoriasis Arthritis, Psoriatic | Phase 3 | 2004-09-01 |
| Completed | A Phase 3b Study to Evaluate Subject Satisfaction With Follitropin Alfa Injection in Oligoanovulatory Infertil Infertility | Phase 3 | 2004-07-01 |
| Completed | Treatment of Abnormal Adipose Tissue Accumulation in Human Immunodeficiency Virus (HIV) Patients HIV Infections, Lipodystrophy | Phase 3 | 2004-05-28 |
| Completed | Rebif® Versus Copaxone® in the Treatment of Relapsing Remitting Multiple Sclerosis Relapsing-remitting Multiple Sclerosis | Phase 4 | 2004-02-16 |
| Completed | An Open Label, Canadian Phase IIIb Study With Ovidrel in Ovulation Induction (OI) and Assisted Reproductive Te Ovulation Induction, Infertility | — | 2003-12-01 |
| Completed | A Study to Compare the Safety and Efficacy of Cetrotide® 3 Milligram (mg) Versus Antagon™ in Women Undergoing Infertile Women Undergoing Assisted Reproductive Technology (ART) | Phase 4 | 2003-09-01 |
| Completed | A Study of the Safety and Effects of EMD 72000 in Subjects With Recurrent Ovarian Cancer Ovarian Cancer | Phase 2 | 2003-04-01 |
| Completed | Rebif® Pregnancy Registry Multiple Sclerosis | — | 2002-12-01 |
| Completed | A Multicenter Phase 3 Study of Interferon-beta-1a for the Treatment of Chronic Hepatitis C in Asian Subjects Hepatitis C | Phase 3 | 2002-09-01 |
| Completed | Sarizotan in Parkinson Patients With L-dopa-induced Dyskinesia Parkinson's Disease, Dyskinesia | Phase 2 | 2002-07-01 |
| Completed | Safety and Efficacy of Interferon-Beta-1a (Rebif®) for Treating Subjects With Acute Symptoms of Ulcerative Col Ulcerative Colitis | Phase 2 | 2001-12-01 |
| Terminated | Safety and Efficacy of Treatment With Interferon Beta-1a Rebif® in Patients With Crohn's Disease Crohn's Disease | Phase 2 | 2001-11-01 |
| Completed | An Efficacy and Safety Trial of Serostim® in the Maintenance of the Treatment Effect Obtained During the Study Human Immunodeficiency Virus-associated Adipose Redistribution Syndrome (HARS), Human Immunodeficiency Virus Infections | Phase 2 / Phase 3 | 2001-09-01 |
| Completed | Safety and Efficacy Trial of Serostim® in the Treatment of Subjects With Human Immunodeficiency Virus-associat Human Immunodeficiency Virus-associated Adipose Redistribution Syndrome (HARS), Human Immunodeficiency Virus Infections | Phase 2 / Phase 3 | 2001-03-01 |
| Completed | Tolerability of Rebif® Injection With and Without the Use of Rebiject™Mini in Relapsing-Remitting Multiple Scl Multiple Sclerosis, Relapsing-remitting | Phase 3 | 2001-01-01 |
| Completed | Interleukin-2 Combined With Monoclonal Antibody Therapy in Treating Patients With Kidney, Bladder, or Lung Can Bladder Cancer, Kidney Cancer, Lung Cancer | Phase 1 | 2000-12-01 |
| Completed | Prospective, Open-label Tolerability and Safety Monitoring Study of Novantrone in a Selected Cohort of Multipl Multiple Sclerosis | — | 2000-10-01 |
| Completed | A Study of Rebif® Compared With Avonex® in the Treatment of Relapsing-remitting Multiple Sclerosis (MS) Multiple Sclerosis, Relapsing-Remitting | Phase 3 | 1999-11-01 |
| Completed | Growth Hormone in the Treatment of HIV-Associated Wasting HIV Infections, HIV Wasting Syndrome | Phase 3 | 1997-07-01 |