Clinical Trials Directory

Trials / Completed

CompletedNCT01085318

Rebif Advanced Magnetic Resonance Imaging (MRI) and Immunology Pilot Trial

A Twenty-four Week, Two Arm, Pilot Trial to Evaluate Remyelination/ Demyelination, Gray Matter Volume and Iron Deposition in the Central Nervous System (CNS) and Immune Status of Subjects With Relapsing-remitting Multiple Sclerosis (RRMS) Treated With Rebif® 44 mcg Subcutaneously (sc) Three Times a Week (Tiw) Compared to a Healthy Control Group

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
38 (actual)
Sponsor
EMD Serono · Industry
Sex
All
Age
18 Years – 65 Years
Healthy volunteers
Accepted

Summary

The purpose of this trial is to evaluate the effects of Rebif® 44 mcg subcutaneous (sc) three times a week (tiw) on a) remyelination/demyelination, b) lesion and brain volume, c) central nervous system (CNS) iron deposition, and d) immune status in subjects with relapsing-remitting multiple sclerosis (RRMS) RRMS via several MRI techniques.

Conditions

Interventions

TypeNameDescription
DRUGRebif44 mcg tiw

Timeline

Start date
2010-06-30
Primary completion
2012-02-29
Completion
2012-03-31
First posted
2010-03-11
Last updated
2018-02-23
Results posted
2013-05-03

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01085318. Inclusion in this directory is not an endorsement.