Trials / Completed
CompletedNCT00004365
Study of Pituitary Size and Function in Familial Dwarfism of Sindh
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 4 (planned)
- Sponsor
- National Center for Research Resources (NCRR) · NIH
- Sex
- All
- Age
- 10 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
OBJECTIVES: I. Assess pituitary size and anatomic configuration by magnetic resonance imaging (MRI) in 4 affected dwarfs in the province of Sindh, Pakistan. II. Evaluate ultradian growth hormone (GH) secretory patterns in 4 affected dwarfs.
Detailed description
PROTOCOL OUTLINE: Pituitary size and anatomy and growth hormone response are evaluated. All patients undergo MRI of the pituitary fossa on day 1. On day 2, homozygous patients receive a slow infusion of normal saline with blood sampling every 10 minutes.
Conditions
Timeline
- Start date
- 1995-09-01
- Completion
- 2000-02-01
- First posted
- 1999-10-19
- Last updated
- 2005-06-24
Source: ClinicalTrials.gov record NCT00004365. Inclusion in this directory is not an endorsement.