| Completed | A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Neonates and I NCT06086626 | Shionogi | Phase 2 |
| Recruiting | Clinical Trial to Study the Efficacy and Safety of Fluorothiazinone (N.F. Gamaleya NRCEM) in Prophylaxis of No NCT06135350 | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | Phase 2 |
| Completed | Pharmacokinetics and Safety of HRS-8427 in Healthy Volunteers and in Patients With Impaired Renal Function NCT07070375 | Jiangsu HengRui Medicine Co., Ltd. | Phase 1 |
| Recruiting | Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative In NCT05639647 | Pfizer | Phase 2 |
| Terminated | Seven Versus 14 Days of Antibiotic Therapy for Multidrug-resistant Gram-negative Bacilli Infections NCT05210387 | Hospital Moinhos de Vento | N/A |
| Completed | Quantifying Gram-negative Resistance to Empiric Therapy in the Intensive Care Unit NCT05171257 | Methodist Health System | — |
| Unknown | The Clinical Character，Risk and Prognosis of Post-neurosurgical Intracranial Infection With Different Pathogen NCT04917380 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Withdrawn | Imipenem/Cilastatin/Relebactam (IMI/REL) in Treatment of CRE Infections NCT04785924 | Wake Forest University Health Sciences | Phase 4 |
| Unknown | Unfractioned Heparin for Treatment of Sepsis Caused by Abdominal Infection NCT04861922 | The Third Xiangya Hospital of Central South University | Phase 3 |
| Completed | A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol i NCT04335539 | Shionogi | Phase 2 |
| Completed | A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Pediatric Part NCT04215991 | Shionogi | Phase 2 |
| Unknown | Comparison of Solid Organ Transplant NCT04055922 | Methodist Health System | — |
| Completed | A Retrospective Observational Study to Evaluate the Utilization, Outcomes, and Adverse Events in Participants NCT03160040 | Rempex (a wholly owned subsidiary of Melinta Therapeutics, Inc.) | — |
| Completed | A Study to Investigate the Intrapulmonary Lung Penetration of Nacubactam in Healthy Participants NCT03182504 | Hoffmann-La Roche | Phase 1 |
| Completed | Effect of Different Colistin Doses on Clinical Outcome of Pediatric Cancer Patients With Gram Negative Infecti NCT03397914 | National Cancer Institute, Egypt | Phase 4 |
| Completed | An Observational Pharmacokinetic Sudy of Ceftolozane-Tazobactam in Intensive Care Unit in Patients With and Wi NCT02962934 | Royal Brisbane and Women's Hospital | — |
| Unknown | Feasibility Studies to Inform Novel Proposals to Avert Community-Based Antimicrobial Resistance Spread NCT02666274 | Guy's and St Thomas' NHS Foundation Trust | — |
| Unknown | Efficacy and Mortality of a Loading Dose of Colistin in Critical Ill Patients NCT02117986 | Hospital Barros Luco Trudeau | Phase 4 |
| Completed | Survey of Severe Infections by Gram Negative Bacteria in Patients Submitted to Stem Cell Transplant NCT02088840 | Gruppo Italiano Trapianto di Midollo Osseo | — |
| Completed | Multicenter Open-label Randomized Controlled Trial (RCT) to Compare Colistin Alone Versus Colistin Plus Merope NCT01732250 | Mical Paul | Phase 4 |
| Unknown | Evaluation of Extended Intravenous of Beta-lactams in the Treatment of Serious Gram-negative Infections in Cri NCT01600768 | National Taiwan University Hospital | N/A |
| Completed | Temocillin Pharmacokinetic in Hemodialysis NCT02285075 | AZ Sint-Jan AV | Phase 4 |
| Completed | Efficacy and Safety Study of Finafloxacin Used in Helicobacter Pylori Infected Patients NCT00723502 | MerLion Pharmaceuticals GmbH | Phase 2 |
| Withdrawn | Surveillance Study - Incidence of Antibiotic Resistance in Serial Gram-negative Bloodstream Isolates NCT00394784 | University of Pittsburgh | — |
| Completed | The Effects of Polymyxin-B Protects on Sepsis Induced Kidney Dysfunction: a Randomized Clinical Trial NCT00490477 | University of Turin, Italy | Phase 3 |
| Completed | Early-Onset Sepsis Surveillance Study NCT00874367 | NICHD Neonatal Research Network | — |
| Suspended | A Randomised Trial on the Saftely and Efficacy of GR270774 in the Treatment of Gram-negative Sepsis in Adult NCT00563134 | Hospital Authority, Hong Kong | N/A |
| Completed | Piperacillin as a Part of Antibiotic Streamlining in the Intensive Care Unit NCT00177814 | University of Pittsburgh | — |
| Completed | Gram Negative Bacteremia, Risk Factors for Failure of Therapy NCT00177957 | University of Pittsburgh | — |
| Completed | Early Use of Polymyxin B Hemoperfusion in Abdominal Sepsis NCT00629382 | St. Bortolo Hospital | Phase 4 |
| Completed | Study Evaluating Tigecycline in Selected Serious Infections Due to Resistant Gram-Negative Organisms NCT00079989 | Wyeth is now a wholly owned subsidiary of Pfizer | Phase 3 |
| Completed | Impact of Continuous Venovenous Haemofiltration on Organ Failure During the Early Phase of Severe Sepsis NCT00406198 | Hopital Lariboisière | Phase 4 |