Trials / Completed
CompletedNCT01732250
Multicenter Open-label Randomized Controlled Trial (RCT) to Compare Colistin Alone Versus Colistin Plus Meropenem
Multicenter Open-label RCT to Compare Colistin Alone vs. Colistin Plus Meropenem
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 406 (actual)
- Sponsor
- Mical Paul · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to determine whether the addition of meropenem to colistin is better than colistin alone in the treatment of clinically significant infections caused by multi-drug resistant bacteria
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Colistin | IV Colistin with loading dose of 9 mil IU units, Maintenance dose 4.5 mil IU q12h, adjusted for renal function, for 10 days. |
| DRUG | Meropenem | IV meropenem, 2 gram q8h, adjusted for renal function, for up to 10 days. |
Timeline
- Start date
- 2013-03-01
- Primary completion
- 2017-01-31
- Completion
- 2017-02-28
- First posted
- 2012-11-22
- Last updated
- 2017-04-12
Locations
7 sites across 3 countries: Greece, Israel, Italy
Source: ClinicalTrials.gov record NCT01732250. Inclusion in this directory is not an endorsement.