Clinical Trials Directory

Trials / Conditions / Genetic Diseases, Inborn

Genetic Diseases, Inborn

40 registered clinical trials studyying Genetic Diseases, Inborn6 currently recruiting.

StatusTrialSponsorPhase
Not Yet RecruitingPrenatal Transplantation for Fetuses With Fanconi Anemia
NCT07408583
Agnieszka CzechowiczPhase 1 / Phase 2
Not Yet RecruitingHealth Economic Evaluation of Non-Invasive Prenatal Exclusion Diagnosis
NCT07469657
Assistance Publique - Hôpitaux de Paris
RecruitingA Study to Learn About the Safety and Efficacy of the Drug Oleogel-S10 in Japanese Patients With Epidermolysis
NCT06917690
Chiesi Farmaceutici S.p.A.Phase 3
RecruitingEffect of Large Neutral Amino Acids in Adults With Classical Phenylketonuria
NCT06337864
Rigshospitalet, DenmarkN/A
CompletedAbsorption, Metabolism, Excretion and Absolute Bioavailability of EDG-5506 in Healthy Volunteers
NCT05730842
Edgewise Therapeutics, Inc.Phase 1
CompletedExtension of AOC 1001-CS1 (MARINA) Study in Adult Myotonic Dystrophy Type 1 (DM1) Patients
NCT05479981
Avidity Biosciences, Inc.Phase 2
RecruitingEvaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thal
NCT05477563
Vertex Pharmaceuticals IncorporatedPhase 3
Active Not RecruitingA Study of Deramiocel (CAP-1002) in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy
NCT05126758
Capricor Inc.Phase 3
Active Not RecruitingEvaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia
NCT05356195
Vertex Pharmaceuticals IncorporatedPhase 3
Active Not RecruitingEvaluating Prenatal Exome Sequencing Study
NCT05290701
Leiden University Medical Center
UnknownGenetic Diagnosis and Human Growth Hormone Treatment in Small for Gestational Age Children With Short Stature
NCT05070234
Chunxiu Gong
Enrolling By InvitationA Long-term Follow-up Study in Participants Who Received CTX001
NCT04208529
Vertex Pharmaceuticals IncorporatedPhase 3
CompletedGuanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader
NCT05657860
Maimonides Medical CenterPhase 4
CompletedWhole Genome Sequencing in the Neonatal Intensive Care Unit
NCT03721458
Milton S. Hershey Medical Center
CompletedDose-finding Study of SPK-8016 Gene Therapy in Patients With Hemophilia A to Support Evaluation in Individuals
NCT03734588
Spark Therapeutics, Inc.Phase 1 / Phase 2
CompletedNYCKidSeq: Incorporating Genomics Into Clinical Care of Diverse NYC Children
NCT03738098
Icahn School of Medicine at Mount SinaiN/A
CompletedLead-in Study to Collect Prospective Efficacy and Safety Data of Current FVIII Prophylaxis Replacement Therapy
NCT03876301
Spark Therapeutics, Inc.
CompletedSubcutaneous Hydrocortisone Children With Congenital Adrenal Hyperplasia
NCT03718234
University of MinnesotaPhase 1
CompletedStudy Evaluating Efficacy and Safety of PF-04965842 and Dupilumab in Adult Subjects With Moderate to Severe At
NCT03720470
PfizerPhase 3
CompletedA Safety and Efficacy Study Evaluating CTX001 in Participants With Transfusion-Dependent β-Thalassemia
NCT03655678
Vertex Pharmaceuticals IncorporatedPhase 2 / Phase 3
CompletedEffect of Benralizumab in Atopic Dermatitis
NCT03563066
McMaster UniversityPhase 2
CompletedStudy to Investigate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years and Over With Moderate to Se
NCT03627767
PfizerPhase 3
CompletedA Study of CAP-1002 in Ambulatory and Non-Ambulatory Patients With Duchenne Muscular Dystrophy
NCT03406780
Capricor Inc.Phase 2
CompletedEvaluating Innovations in Transition From Pediatric to Adult Care - The Transition Navigator Trial
NCT03342495
University of CalgaryN/A
UnknownStudy on the Mechanism of Neurodevelopment Dysplasia of Fetal Brain Caused by ASNS Gene Mutation
NCT03587155
The First Hospital of Jilin University
CompletedLong-Term Outcomes of Ataluren in Duchenne Muscular Dystrophy
NCT03179631
PTC TherapeuticsPhase 3
UnknownUterine Irrigation Method in Infertility Patients Who Require PGD
NCT02676479
Istanbul UniversityN/A
TerminatedNatural History Study of Children With Metachromatic Leukodystrophy
NCT01963650
Shire
CompletedUtilizing Free DNA in Embryo Culture for PGT
NCT02884063
Al Baraka Fertility Hospital
TerminatedAn Extension Study of Ataluren (PTC124) in Participants With Nonsense Mutation Dystrophinopathy
NCT02090959
PTC TherapeuticsPhase 3
CompletedPilot Study of Cardiac MR in Patients With Muscular Dystrophy
NCT02921321
Children's National Research Institute
CompletedPhase 3 Study of Ataluren in Participants With Nonsense Mutation Duchenne Muscular Dystrophy (nmDMD)
NCT01826487
PTC TherapeuticsPhase 3
CompletedAn Analysis of the Symptomatic Domains Most Relevant to Charcot Marie Tooth Neuropathy (CMT) Patients
NCT02429947
University of South Florida
CompletedAn Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patie
NCT00694109
Kastle Therapeutics, LLCPhase 3
CompletedStudy to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemi
NCT00607373
Kastle Therapeutics, LLCPhase 3
CompletedOpen Label Extension of ISIS 301012 (Mipomersen) to Treat Familial Hypercholesterolemia
NCT00477594
Kastle Therapeutics, LLCPhase 2
CompletedHigh-Density Lipoprotein (HDL) Treatment Study
NCT00458055
McGill University Health Centre/Research Institute of the McGill University Health CentreN/A
CompletedMeasure Liver Fat Content After ISIS 301012 (Mipomersen) Administration
NCT00362180
Kastle Therapeutics, LLCPhase 2
CompletedRilonacept for Treatment of Cryopyrin-Associated Periodic Syndromes (CAPS)
NCT00288704
Regeneron PharmaceuticalsPhase 3
AvailableManaged Access Program for Del-zota in Participants With DMD Mutations Amenable to Exon 44 Skipping
NCT07250737
Avidity Biosciences, Inc.