| Completed | A Study of the Safety and Efficacy of Two Different Regimens of Mipomersen in Patients With Familial Hyperchol Hypercholesterolemia, Heterozygous Familial | Phase 3 | 2011-12-01 |
| Completed | Study to Assess the Effects of Mipomersen on Lipid and Lipoprotein Metabolism in Healthy Subjects Healthy Volunteer | Phase 1 | 2011-09-01 |
| Completed | A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Single Doses of Mipomersen in Japanese H Healthy Volunteer | Phase 1 | 2011-01-01 |
| Completed | A Study to Determine the Effects of Multiple Doses of Mipomersen (200 mg SC) on the Pharmacodynamics and Pharm Healthy | Phase 1 | 2010-05-01 |
| Completed | A Study to Evaluate the Effect of Mipomersen on Cardiac Repolarization Conducted in Healthy Subjects Healthy | Phase 1 | 2010-03-01 |
| Completed | A Study to Evaluate 3 Different Dosing Regimens of Mipomersen Administered Via Subcutaneous Injections to Heal Healthy Volunteer | Phase 1 | 2010-01-01 |
| Completed | Safety and Efficacy of Mipomersen in Patients With Severe Hypercholesterolemia on a Maximally Tolerated Lipid- Hypercholesterolemia, Coronary Heart Disease | Phase 3 | 2009-01-01 |
| Completed | Safety and Efficacy of Mipomersen (ISIS 301012) As Add-on Therapy in High Risk Hypercholesterolemic Patients Hypercholesterolemia, Coronary Heart Disease | Phase 3 | 2008-11-01 |
| Completed | Safety and Efficacy Study of ISIS 301012 (Mipomersen) Administration in High Risk Statin Intolerant Subjects Metabolic Diseases, Hyperlipidemias, Metabolic Disorder | Phase 2 | 2008-10-01 |
| Completed | Efficacy and Safety Study of ISIS 301012 (Mipomersen) as Add-on in Familial Hypercholesterolemic Patients With Heterozygous Familial Hypercholesterolemia, Coronary Artery Disease | Phase 3 | 2008-07-01 |
| Completed | An Open-label Extension Study to Assess the Long-term Safety and Efficacy of ISIS 301012 (Mipomersen) in Patie Lipid Metabolism, Inborn Errors, Hypercholesterolemia, Autosomal Dominant, Hyperlipidemias | Phase 3 | 2008-04-01 |
| Completed | Study to Assess the Safety and Efficacy of ISIS 301012 (Mipomersen) in Homozygous Familial Hypercholesterolemi Lipid Metabolism, Inborn Errors, Hypercholesterolemia, Autosomal Dominant, Hyperlipidemias | Phase 3 | 2007-07-01 |
| Completed | Open Label Extension of ISIS 301012 (Mipomersen) to Treat Familial Hypercholesterolemia Lipid Metabolism, Inborn Errors, Hypercholesterolemia, Autosomal Dominant, Hyperlipidemias | Phase 2 | 2007-05-01 |
| Completed | Measure Liver Fat Content After ISIS 301012 (Mipomersen) Administration Lipid Metabolism, Inborn Errors, Hyperlipidemias, Metabolic Diseases | Phase 2 | 2006-07-01 |
| Completed | Study of ISIS 301012 (Mipomersen) in Heterozygous Familial Hypercholesterolemia Subjects on Lipid Lowering The Hypercholesterolemia, Familial | Phase 2 | 2006-02-01 |
| Completed | Dose-escalating Safety Study of ISIS 301012 in Homozygous Familial Hypercholesterolemia Subjects on Lipid Lowe Hypercholesterolemia, Familial | Phase 2 | 2006-01-01 |
| Completed | Dose-escalating Safety Study in Subjects on Stable Statin Therapy Hypercholesterolemia | Phase 2 | 2005-09-01 |
| Completed | Safety and Tolerability of Varying Load and Dose of ISIS 301012 in People With Elevated LDL-cholesterol Levels Hypercholesterolemia | Phase 2 | 2005-08-01 |