Clinical Trials Directory

Trials / Unknown

UnknownNCT05070234

Genetic Diagnosis and Human Growth Hormone Treatment in Small for Gestational Age Children With Short Stature

Genetic Diagnosis and the Response to Recombinant Human Growth Hormone Treatment in Small for Gestational Age Children With Short Stature

Status
Unknown
Phase
Study type
Observational
Enrollment
150 (estimated)
Sponsor
Chunxiu Gong · Academic / Other
Sex
All
Age
2 Years – 20 Years
Healthy volunteers
Not accepted

Summary

This study is a multi-center, retrospective and non-interventional research. In this study, a total of 150 short children who were small for gestational age and had been treated with recombinant human growth hormone (rhGH) are selected for genetic testing. The aims of this study are to analyze the genetic etiology of SGA children with short stature, and to compare the efficacy and safety of rhGH treatment in subjects with different etiologies.

Conditions

Interventions

TypeNameDescription
GENETICBlood collection for genetic analysisGenetic tests in this study are sequential testing, including MS-MLPA, whole exome sequencing, whole genome sequencing, as well as RNA-seq.

Timeline

Start date
2021-10-11
Primary completion
2022-08-30
Completion
2022-08-30
First posted
2021-10-07
Last updated
2021-10-07

Source: ClinicalTrials.gov record NCT05070234. Inclusion in this directory is not an endorsement.