| Recruiting | Copper Supplementation in Cirrhosis NCT07471542 | University of Washington | N/A |
| Recruiting | A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD NCT07333183 | Pulmovant, Inc. | Phase 2 |
| Recruiting | Reversing External-beam Radiotherapy-associated Fibrosis Syndrome: an Interventional Bayesian Adaptive Randomi NCT06912763 | M.D. Anderson Cancer Center | Phase 2 |
| Recruiting | Systemic Therapy of Open-label Prophylactic Pravastatin or Pentoxifylline/Tocopherol Prevention of Lymphedema NCT06494111 | M.D. Anderson Cancer Center | Phase 2 |
| Completed | Effectiveness of Percutaneous Electrolysis in Subacute and Early Chronic Medial Gastrocnemius Muscle Injuries NCT06713200 | University of Salamanca | N/A |
| Active Not Recruiting | A Study of Mosliciguat in PH-ILD NCT06635850 | Pulmovant, Inc. | Phase 2 |
| Recruiting | The Gastric Bypass Stent System as a Treatment for Hepatic Fibrosis in Obese Patients in European Region NCT06561529 | MDCECRO LLC | N/A |
| Unknown | Subcutaneous Semaglutide in Systemic Scleroderma NCT06149260 | Second Xiangya Hospital of Central South University | Phase 1 |
| Active Not Recruiting | Radiological Spectrum Of Fatty Liver Correlate With High Resolution Ultrasonography Of Fibrosis And Cirrhosis NCT06749522 | Superior University | — |
| Recruiting | Evaluation of the Medical Benefit of Spa Therapy on Fibrosis After Radiotherapy for Breast Cancer or UADT (Upp NCT05874492 | Association Francaise pour la Recherche Thermale | N/A |
| Unknown | Effect of Modified Complete Decongestive Therapy on Lower Limbs Fibrosis Post Cellulitis NCT05661123 | Cairo University | N/A |
| Recruiting | Diaphragmatic Function as a Biomarker NCT05903001 | RWTH Aachen University | — |
| Active Not Recruiting | Myocardial Fibrosis in Patients With Permanent Pacemakers NCT05920226 | Ryazan State Medical University | — |
| Unknown | Multiple Ascending Dose Study of CG200745 'Ivaltinostat' Oral Capsule NCT05716919 | Machaon Biotherapeutics, Inc. | Phase 1 |
| Recruiting | Evaluation of Electrode-modiolus Distance and Cochlear Fibrosis Using Depth Sounding and Spectroscopy Tools NCT05402969 | University Hospital, Montpellier | — |
| Unknown | Physiotherapy for Arthrofibrosis Following Knee Replacement. NCT05459259 | University of Nottingham | — |
| Active Not Recruiting | Assess the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of RXC007 in Idiopathic Pulmonary NCT05570058 | Redx Pharma Ltd | Phase 2 |
| Recruiting | Screening and Follow-up in Patients With HIV Infection Combined With Metabolic Associated Fatty Liver Disease NCT05330923 | Peking Union Medical College Hospital | — |
| Completed | Efficacy and Safety of Longidaza® for the Treatment of Patients With Residual Changes in the Lungs After COVID NCT06383819 | NPO Petrovax | Phase 3 |
| Unknown | Pilot Study of the Predictive Value of TREM1 Expression and Activation in Inflammation and Radio-induced Mamma NCT04948840 | Centre Francois Baclesse, Luxembourg | N/A |
| Completed | Growth Hormone in Decompensated Liver Cirrhosis NCT05253287 | Post Graduate Institute of Medical Education and Research, Chandigarh | Phase 2 / Phase 3 |
| Completed | Evaluation of Advanced US Tools in Assessing Allograft Complications NCT04423458 | Imperial College London | — |
| Completed | Covid-19 Respiratory Sequelae French Cohort NCT05075785 | Centre Hospitalier Universitaire, Amiens | — |
| Completed | Low-Level Laser in Head and Neck Chronic Lymphedema NCT04482855 | Abramson Cancer Center at Penn Medicine | N/A |
| Completed | Saroglitazar Magnesium for the Treatment of Nonalcoholic Steatohepatitis With Fibrosis NCT05011305 | Zydus Therapeutics Inc. | Phase 2 |
| Unknown | Growth Hormone as a Model for Reversible Activation of Adipose Tissue Fibrosis NCT04998500 | University of Aarhus | N/A |
| Completed | Study of Oral Idebenone to Treat Non-Alcoholic Steatohepatitis NCT04669158 | Stanford University | Phase 1 / Phase 2 |
| Not Yet Recruiting | THE FRENCH NATIONAL NAFLD COHORT (FRench pAtients With MEtabolic Steatosis) NCT04925362 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | A 3-part Study to Evaluate Safety, Tolerability, Food Effect and Drug-drug Interactions of RXC007 in Healthy V NCT04931147 | Redx Pharma Ltd | Phase 1 |
| Unknown | Cohort Follow-up of Survivors of Hospitalization for COVID-19 During the 2nd Wave of the Epidemic in France NCT04934202 | Assistance Publique - Hôpitaux de Paris | — |
| Unknown | 68Ga-FAPI PET/CT in Patients With Various Fibrotic Disease NCT04831034 | First Affiliated Hospital of Fujian Medical University | EARLY_Phase 1 |
| Withdrawn | Healthy Volunteer Study Comparing Tablet and Capsule Formulations NCT04001998 | Blade Therapeutics | Phase 1 |
| Completed | A Healthy Volunteer Study of PBI-4050 NCT04695041 | Liminal BioSciences Ltd. | Phase 1 |
| Unknown | Urethral Stricture After Transurethral Resection of the Prostate/Bladder: a Prospective Study of Risk Factors NCT04795570 | University Hospital Virgen de las Nieves | — |
| Terminated | Losartan to Improve Hip Microfracture NCT04212650 | Steadman Philippon Research Institute | Phase 1 / Phase 2 |
| Unknown | The Impact of Conventional Hemodialysis and Renal Transplantation on the Global Longitudinal Strain of the Lef NCT05685823 | Grigore T. Popa University of Medicine and Pharmacy | — |
| Completed | Identification of Biomarkers Related to Liver Fibrosis as New Therapeutic Targets NCT03979417 | Institut Pasteur | — |
| Completed | Zinc Status and Growth in Cystic Fibrosis NCT04302428 | Indiana University | — |
| Completed | Human Absorption, Distribution and Metabolism Study (hAME) [14C]-KD025 NCT03907540 | Kadmon Corporation, LLC | Phase 1 |
| Completed | Light Emitting Diode-Red Light (LED-RL) Phototherapy for Skin Scarring Prevention NCT03795116 | State University of New York - Downstate Medical Center | Phase 2 |
| Completed | Low-Level Laser in Treatment of Head and Neck Lymphedema: A Pilot Study NCT03738332 | University of Pennsylvania | N/A |
| Terminated | Pathology and Imaging in Kidney Allografts NCT03780101 | NHS Greater Glasgow and Clyde | — |
| Recruiting | Fibro-inflammatory Progression From Acute to Chronic Pancreatitis NCT03853447 | Copenhagen University Hospital, Hvidovre | — |
| Terminated | Validation of Point of Care Liver Function Tests NCT03800069 | University of Pennsylvania | — |
| Unknown | Clinical Benefit of Spa Care on Severe Radiation-induced Fibrosis After Postoperative Radiotherapy for Breast NCT02898376 | Institut de Cancérologie de Lorraine | Phase 3 |
| Active Not Recruiting | Manual Therapy in Treating Fibrosis-Related Late Effect Dysphagia in Head and Neck Cancer Survivors NCT03612531 | M.D. Anderson Cancer Center | N/A |
| Completed | First in Human Study in Healthy Volunteers Followed With Dosing in Participants With Lung or Liver Fibrosis NCT03559166 | Blade Therapeutics | Phase 1 |
| Completed | Self-Care for Head and Neck Cancer Survivors With Lymphedema and Fibrosis NCT03030859 | University of Pennsylvania | N/A |
| Unknown | Evaluating the Effect of Spironolactone on Hypertrophic Cardiomyopathy NCT02948998 | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | Phase 4 |
| Unknown | Phase 1 Study of HF-LED-RL in Fitzpatrick Skin Types I to III NCT03433222 | VA Northern California Health Care System | Phase 1 |
| Recruiting | Screening At-risk Populations for Hepatic Fibrosis With Non-invasive Markers NCT03308916 | Maja Thiele | N/A |
| Completed | Efficacy and Safety of Tigerase® vs. Pulmozyme® in Patients With Cystic Fibrosis NCT04468100 | AO GENERIUM | Phase 3 |
| Terminated | A Study to Evaluate the Efficacy and Safety of CC-90001 in Subjects With Idiopathic Pulmonary Fibrosis NCT03142191 | Celgene | Phase 2 |
| Completed | A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-98626 NCT03142165 | Bristol-Myers Squibb | Phase 1 |
| Completed | RNA and Heat Shock Protein Biomarkers in Radiation-induced Fibrosis in Breast Cancer NCT03000764 | Institut de Cancérologie de Lorraine | N/A |
| Unknown | Amniotic Membrane Wrapping and Tenolysis Versus Tenolysis Alone for Treatment of Tendon Adhesions of the Hand/ NCT03013582 | Thomas Jefferson University | N/A |
| Withdrawn | Comparison of EUS-Guided Liver Biopsy With Percutaneous Liver Biopsy NCT02947516 | Brigham and Women's Hospital | N/A |
| Completed | A Study of Safety, Tolerability, and the Effects Two ND-L02-s0201 Have on the Body NCT03241264 | Bristol-Myers Squibb | Phase 1 |
| Completed | The Alfred Step Test Exercise Protocol (A-STEP), for Adults With Cystic Fibrosis. NCT02717650 | The Alfred | N/A |
| Withdrawn | Midodrine, Octreotide and Albumin: Impact on Renal Function of Patients With Liver Cirrhosis and Renal Failure NCT01587222 | Anna Cruceta | Phase 2 |
| Unknown | Examination the Ability to Early Diagnose HCC by Combining Three Biomarkers Technology Developed by WAKO, And NCT02826005 | Ilex Medical | N/A |
| Completed | Efficacy of Delayed Enhancement MRI-Guided Ablation vs Conventional Catheter Ablation of Atrial Fibrillation NCT02529319 | Tulane University School of Medicine | N/A |
| Completed | Imaging FIB ONE in the Human Lung Using Endomicroscopy NCT02604862 | University of Edinburgh | EARLY_Phase 1 |
| Completed | B-mode Ultrasound Imaging in Detecting Early Liver Cancer NCT02774161 | Stanford University | N/A |
| Completed | Emricasan, a Caspase Inhibitor, for Evaluation in Subjects With Non-Alcoholic Steatohepatitis (NASH) Fibrosis NCT02686762 | Conatus Pharmaceuticals Inc. | Phase 2 |
| Completed | High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin NCT02630303 | Jared Jagdeo, MD, MS | Phase 1 |
| Completed | The Prevalence and Severity of HCV Infection in Thalassemia Major and Thalassemia Intermedia in Siriraj Hospit NCT02904252 | Mahidol University | — |
| Completed | Hepatic Fibrosis Assessment Using Multiparametric Magnetic Resonance Imaging NCT02480972 | Seoul National University Hospital | N/A |
| Unknown | Prospective Evaluation of HIV Patients Using Non-invasive Methods for Estimation of Liver Fibrosis and Steatos NCT02542020 | Oswaldo Cruz Foundation | — |
| Completed | Magnetic Resonance Imaging and Fibrosis NCT02790008 | Linkoeping University | — |
| Completed | Establishing Lymphedema and Fibrosis Measures in Oral Cancer Patients NCT02412241 | Vanderbilt-Ingram Cancer Center | N/A |
| Active Not Recruiting | Hypofractionated Loco-regional Adjuvant Radiation Therapy of Breast Cancer Combined With a Simultaneous Integr NCT02384733 | Danish Breast Cancer Cooperative Group | N/A |
| Unknown | Emtricitabine Plus Adefovir Dipivoxil for Naive Chinese HBV Related Cirrhosis Patients NCT02327689 | Asian-Pacific Alliance of Liver Disease, Beijing | Phase 4 |
| Unknown | Knee Stiffness in Fibrosis Diathesis NCT02294890 | University Hospital Pellenberg | — |
| Unknown | Inflammation and Obesity-associated Disease NCT02322073 | Göteborg University | — |
| Completed | Losartan to Reduce Inflammation and Fibrosis Endpoints in HIV Trial NCT02049307 | Hennepin Healthcare Research Institute | Phase 2 |
| Terminated | Study to Evaluate Fractional Collagen Synthesis Within Keloid Scars and Identify Biomarkers of Keloid Scars NCT01978301 | GlaxoSmithKline | Phase 1 |
| Unknown | Mesenchymal Stromal Cell Therapy in Renal Recipients NCT02057965 | Leiden University Medical Center | Phase 2 |
| Unknown | Assessment Of Liver and Spleen Fibrosis in Patients With Gaucher Disease Using Fibroscan NCT01898325 | Rambam Health Care Campus | N/A |
| Completed | Hepatic Fibrosis Non-invasive Methods Questionnaire NCT02132351 | Al-Azhar University | — |
| Recruiting | Blood Collection Biorepository for Liver Disease Research NCT03025074 | State University of New York at Buffalo | — |
| Completed | Placebo Controlled Evaluation of the Cell Mediated Immune Response of Cirrhotic Subjects to Zostavax™ NCT02958345 | Tulane University | Phase 4 |
| Completed | Angiogenesis and Fibrosis in Myocardial Infarction NCT01813045 | University of Edinburgh | — |
| Completed | Angiogenesis and Fibrosis in Aortic Stenosis NCT01837160 | University of Edinburgh | — |
| Unknown | Transitional Care Interventions for Patients With Cirrhosis Post-TIPS NCT02877953 | Shihezi University | N/A |
| Completed | Fibrosis a New Pathological Actor in Adipose Tissue NCT01655017 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Integrated Care for Patients With High Risk Substance Use and Psychiatric Disorder With Chronic Direct Acting NCT02648022 | VA Office of Research and Development | N/A |
| Completed | HIV Accelerated Liver Disease in Uganda NCT01524562 | National Institute of Allergy and Infectious Diseases (NIAID) | — |
| Completed | Study on Immunopathogenesis in HIV and Hepatitis C Coinfection NCT01296529 | Rush University Medical Center | — |
| Withdrawn | Examination of Left Atrial Fibrosis Using MRI NCT01233674 | University of Pittsburgh | — |
| Terminated | A Study to Characterize the Safety, PK and Biological Activity of CC-930 in Idiopathic Pulmonary Fibrosis (IPF NCT01203943 | Celgene | Phase 2 |
| Completed | International T1 Multicentre CMR Outcome Study NCT02407197 | King's College London | — |
| Completed | Curative Efficacy of Pravastatine in Patients Presented Delayed Cutaneous and Subcutaneous Radio-induced Fibro NCT01268202 | Gustave Roussy, Cancer Campus, Grand Paris | Phase 2 |
| Unknown | Human Menstrual Blood-derived Mesenchymal Stem Cells for Patients With Liver Cirrhosis NCT01483248 | S-Evans Biosciences Co., Ltd. | Phase 1 / Phase 2 |
| Unknown | Treatment of Radiation-induced Fibrosis in the Upper Aerodigestive Tract Cancer by a Combination of Pentoxifyl NCT01822405 | Hospital Universitario de Canarias | Phase 2 |
| Completed | The Fibrosis-Lymphedema Continuum in Head and Neck Cancer NCT01187173 | Vanderbilt University | — |
| Completed | Use of Bevacizumab in Trabeculectomy Surgery NCT01166594 | Sunnybrook Health Sciences Centre | Phase 4 |
| Unknown | Non-Invasive Evaluation of Fibrosis and Steatosis in Chronic Hepatopathy NCT01246388 | Tischendorf, Jens, M.D. | — |
| Completed | Utility of Prolonged-release Pirfenidone in the Progression of Chronic Kidney Disease NCT02408744 | University of Guadalajara | Phase 1 / Phase 2 |
| Completed | Prospective Clinical Trials on Skin Wound Healing in Young and Aged Individuals NCT01040104 | Medical University of Vienna | — |
| Completed | Safety of Gadovist in Renally Impaired Patients NCT00828737 | Bayer | Phase 4 |
| Completed | Risk of Nephrogenic Systemic Fibrosis (NSF) in Patients With Moderate Renal Insufficiency After the Administra NCT00744939 | Bayer | — |
| Completed | Polymorphisms of Fibrosis-Relating Genes on Outcome of HCV-Related Chronic Liver Disease NCT00629603 | Kaohsiung Medical University Chung-Ho Memorial Hospital | N/A |
| Completed | Safety and Efficacy Study of Depelestat in Acute Respiratory Distress Syndrome (ARDS) Patients NCT00455767 | Debiopharm International SA | Phase 2 |
| Completed | Peginterferon Alpha-2a Maintenance Therapy for Portal Hypertension in Patients With Hepatitis C NCT00252642 | Virginia Commonwealth University | N/A |
| Completed | Usefulness of Topical Non-Steroidal Anti-Inflammatory Drugs or Steroids Before Trabeculectomy and Clinical Out NCT00707421 | Universitaire Ziekenhuizen KU Leuven | Phase 3 |
| Completed | Pirfenidone, an Antifibrotic and Antiinflammatory Drug NCT02161952 | University of Guadalajara | Phase 2 |
| Completed | Adefovir Dipivoxil For The Treatment Of Patients With Chronic Hepatitis B Related Advanced Fibrosis Or Cirrhos NCT00347009 | GlaxoSmithKline | Phase 4 |
| Completed | Pergolide Treatment and Valvular Heart Disease NCT00234364 | Århus Amt | — |
| Unknown | Efficacy of Prazosin Versus Placebo Associated With Peg-Interferon Alpha 2b and Ribavirin in Chronic Hepatitis NCT00148837 | French National Agency for Research on AIDS and Viral Hepatitis | Phase 2 |
| Completed | Trental & Vitamin E for Radiation-Induced Fibrosis NCT00583700 | University of Iowa | Phase 2 |
| Completed | Effect of Vitamin E on Pediatric Nonalcoholic Fatty Liver Disease (NAFLD) NCT00655018 | Bambino Gesù Hospital and Research Institute | Phase 2 / Phase 3 |
| Completed | PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to Alpha-Interferon Plus NCT00039871 | Merck Sharp & Dohme LLC | Phase 3 |
| Completed | Pirfenidone to Treat Kidney Disease (Focal Segmental Glomerulosclerosis) NCT00001959 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 2 |
| Completed | Combination Drug Therapy for Patients With Hepatitis C NCT00001729 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 3 |
| Completed | Trial of Pentoxifylline in Patients With Functional Disability Caused by Radiation-Induced Advanced Regional F NCT00001437 | National Cancer Institute (NCI) | Phase 2 |