NCT02480972

Hepatic Fibrosis Assessment Using Multiparametric Magnetic Resonance Imaging

Hepatic Fibrosis Assessment Using Multiparametric Magnetic Resonance Imaging (MRI)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 69 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to assess degree of hepatic fibrosis using multiparametric MRI for investigating difference between normal or early fibrosis and advanced fibrosis.

Detailed description

In patients with liver parenchymal disease or normal liver parenchyma who are scheduled to undergo either liver resection or liver biopsy are included. Referred patients undergo multiparametric MRI including perfusion, diffusion, elastography and fat quantification before surgery or biopsy. The pathophysiologic changes are evaluated using multiparametric MRI, and compared between normal/early fibrosis and advanced fibrosis.

Conditions

• Fibrosis
• Cirrhosis

Interventions

Type	Name	Description
PROCEDURE	magnetic resonance imaging	multiparametric MRI as follows: 1. diffusion weighted imaging using multiple b-values 2. Fat quantification sequence 3. perfusion MRI using ECCM agent 4. MR elastography \------------------------------------ 5. routine MRI using hepatocyte specific agent (optional in patients with focal liver lesion)

Timeline

• Start date: 2015-06-23
• Primary completion: 2016-09-20
• Completion: 2020-08-28
• First posted: 2015-06-25
• Last updated: 2021-12-17

Locations

1 site across 1 country: South Korea