| Not Yet Recruiting | Infant Massage for Lymphedema and Comfort in Preterm Newborns NCT07418814 | Erzurum Technical University | N/A |
| Not Yet Recruiting | Care Bundle for Prevention of Skin Complications and Edema in Restrained Patients NCT07442344 | Kocaeli City Hospital | N/A |
| Recruiting | Effects of Red and Infrared Photobiomodulation in Rhinoplasty at a Single Centre NCT07033039 | University of Nove de Julho | N/A |
| Withdrawn | Steroids for Rhinoplasty: Pain, Nausea, Edema and Ecchymosis NCT06483204 | Vanderbilt University Medical Center | Phase 4 |
| Completed | Comparing Natriuretic Effects of ER Torsemide to IR Torsemide in Patients With Heart Failure NCT06995144 | Sarfez Pharmaceuticals, Inc. | Phase 4 |
| Enrolling By Invitation | Lymphatic Drainage Massage and Melatonin in Post-Orthognathic Surgery Pain and Edema NCT07062757 | Bezmialem Vakif University | N/A |
| Completed | Single-Session Extraoral PBM After Third Molar Extraction NCT07522918 | Konya Necmettin Erbakan Üniversitesi | N/A |
| Not Yet Recruiting | Naturally Controlled Decongestion Using Renal Independent System in ADHF Patients, a European Registry NCT06401109 | AquaPass Medical Ltd. | N/A |
| Recruiting | Muscle and Subcutaneous Tissue Variation by Ultrasound and Impedance Linked to Fluid Balance in ICU Patients NCT06697470 | Dr F Duprez | — |
| Enrolling By Invitation | COMPARISON OF BANDAGE IN HAND EDEMA NCT06938048 | Regione del Veneto - AULSS n. 7 Pedemontana | N/A |
| Recruiting | Efficacy and Safety of Combination Diuretic Therapy in Patients With Acute Decompensated Heart Failure and Vol NCT06414759 | Cairo University | Phase 4 |
| Completed | Negative Pressure Wound Therapy in Oral Surgery NCT06758258 | Tokat Gaziosmanpasa University | N/A |
| Recruiting | Diuretic Tuner Clinical Decision Support NCT04759274 | University of Texas Southwestern Medical Center | N/A |
| Unknown | Detecting Fluid Accumulation With a Wearable Bioimpedance Sensor NCT06053710 | Mode Sensors AS | N/A |
| Recruiting | Surgical Evaluation for Upper Extremity Lymphedema (BioBridge) NCT05695924 | Fibralign Corporation | N/A |
| Completed | Transcutaneous Auricular Vagus Nerve Stimulation in Upper Extremity Lymphedema NCT06069908 | Seda Saka | N/A |
| Completed | Contributing Factors to Local Bioimpedance Spectroscopy NCT06003205 | Mode Sensors AS | N/A |
| Completed | Control of Edema in the Knee in Patients With Knee Osteoarthritis NCT06010394 | Uskudar University | N/A |
| Unknown | Examination of Edema After Arthroscopic Shoulder Surgery NCT06014203 | Gazi University | — |
| Completed | Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DM NCT06011798 | Unity Biotechnology, Inc. | Phase 2 |
| Completed | A Non-randomized, Open-Label Study to Evaluate the Safety and Effectiveness of Insight® Pro Device for Evaluat NCT05628688 | Koya Medical, Inc. | — |
| Completed | Use of Red Light Emitting Diode (LED) and Polydioxanone Thread in Glabellar Wrinkles NCT05720000 | University of Nove de Julho | N/A |
| Completed | Comparison of Isotonic Versus Hypotonic Fluids in Neonates for Maintenance Fluid Therapy After Surgery NCT06484608 | Rawalpindi Medical College | N/A |
| Completed | Foot and Ankle Post-operative Oedema Management Using Geko™ NCT04927234 | Firstkind Ltd | N/A |
| Unknown | Effect of Intraoperative Taping on the Control of Edema Resulting From Stripping NCT05534308 | University of Sao Paulo | N/A |
| Completed | Lornoxicam Versus Etodolac After Third Molar Surgery NCT05679453 | Kutahya Health Sciences University | Phase 4 |
| Completed | The Efficacy of Kinesiotaping on Pain, Edema and Functionality After Total Knee Arthroplasty NCT05457686 | Kirsehir Ahi Evran Universitesi | N/A |
| Recruiting | Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome. NCT05505500 | University of Michigan | — |
| Completed | Effectiveness Of Tranexamic Acıd Application Wıth Different Doses On Bleeding, Edema And Physician Comfort In NCT06301204 | Bezmialem Vakif University | N/A |
| Completed | AquaPass Device in Treatment of CHF Patients NCT05843201 | AquaPass Medical Ltd. | N/A |
| Completed | The Impact of Arnica Montana Following the Surgical Extraction of Impacted Third Molars NCT06193720 | Saint-Joseph University | N/A |
| Unknown | PVP-Guided Decongestive Therapy in HF NCT05217342 | Marmara University | Phase 4 |
| Unknown | The Effect of Local Tranexamic Acid on Post-operative Edema and Ecchymosis in Eyelid Surgery NCT04951128 | Consultants in Ophthalmic and Facial Plastics Surgery | Phase 4 |
| Completed | Topical Tranexamic Acid Application in Rhinoplasty NCT05326139 | Baskent University | Phase 4 |
| Completed | A Comparison of Volatile Anesthesia and Total Intravenous Anesthesia (TIVA) NCT04773002 | Tokat Gaziosmanpasa University | — |
| Completed | Effects of Sterile Kinesio Tape on Anterior Cruciate Ligament Reconstruction NCT04873921 | Baskent University | N/A |
| Active Not Recruiting | GOREISAN for Heart Failure (GOREISAN-HF) Trial NCT04691700 | Takeshi Morimoto | Phase 4 |
| Completed | A Dual-center Study Evaluating Clinical Acceptance of a NPWT Wound Care System NCT04593693 | Medela AG | N/A |
| Completed | Bromelain and Escin in the Reduction of Postoperative Sequelae in Periodontal and Implant Surgery NCT04657874 | University of L'Aquila | N/A |
| Recruiting | LymphBridge: Surgical Evaluation for Breast Cancer-Associated Lymphedema (BioBridge) NCT04606030 | Fibralign Corporation | N/A |
| Completed | Lymphatic Function in Patients With Secondary Tricuspid Valve Regurgitation NCT04595448 | University of Aarhus | — |
| Completed | Effect of Electroacupuncture in Patients Submitted Orthognathic Surgery and Mentoplasty NCT05310019 | University of Nove de Julho | N/A |
| Terminated | Amiloride in Nephrotic Syndrome NCT05079789 | University Hospital Tuebingen | Phase 3 |
| Recruiting | Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Stan NCT04278404 | Duke University | — |
| Completed | Point of Care Ultrasound Measurements of Perioperative Edema in Infants With Congenital Heart Disease NCT04151160 | University of Colorado, Denver | — |
| Completed | Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema NCT05466604 | Hacettepe University | Phase 4 |
| Completed | Evaluation of the Action of MOBIDERM® on Periarticular Edema After Total Knee Prosthesis - Randomized Controll NCT03867305 | Centre Hospitalier Universitaire de Nīmes | N/A |
| Unknown | Effectiveness of Khat on Eyelid Wound Healing After Oculoplastic Surgery - a Prospective Study. NCT03917641 | Sheba Medical Center | N/A |
| Completed | Correlation of Clinical and Laboratory Findings and Diuretic Efficacy in Patients With Edematous States in the NCT03967717 | University of Cologne | — |
| Completed | Soft Part Management for Surgical Fractures of the Lower Limb NCT03915223 | University Hospital, Clermont-Ferrand | N/A |
| Active Not Recruiting | Screening For BCRL In Targeted Therapy For Breast Cancer NCT05142800 | Massachusetts General Hospital | — |
| Completed | Tongue Depressor-related Ischemia-Reperfusion Injury in Tongue NCT04205253 | Selcuk University | — |
| Unknown | Effectiveness of Light-emitting Diode (LED) Photobiomodulation in the Extraction of Retained Lower Third Molar NCT03442166 | University of Nove de Julho | Phase 2 |
| Completed | The Effect of Complex Decongestive Therapy in Patients With Lymphedema NCT06220903 | Medipol University | N/A |
| Withdrawn | Effect of Vitrectomy on the Evolution of Refractory Diabetic Macular Edema NCT03603990 | Fondation Ophtalmologique Adolphe de Rothschild | N/A |
| Completed | An Approach to Reduce Uvula Edema After Tonsillectomy NCT03079453 | Bezmialem Vakif University | Phase 4 |
| Completed | Investigation of the Effects of CGF and A-PRF on Pain, Edema and Trismus After Impacted Lower Third Molar Surg NCT03690167 | Dr. Damla Torul | N/A |
| Unknown | The Mount Sinai Diabetic Foot Ulcer Prospective Trial NCT03404895 | Windsor Ting | N/A |
| Completed | Effect of CGF on Short Term Clinical Outcomes After Partially Impacted Mandibular Third Molar Surgery NCT03913884 | Ege University | N/A |
| Unknown | Kinesio Tex Tape in Reducing Edema and Seroma After Complex Reconstructive Breast Surgery NCT03477565 | IRCCS San Raffaele | N/A |
| Completed | Effect of Compression Therapy on Postoperative Swelling and Pain After Total Knee Arthroplasty NCT03490409 | Naestved Hospital | N/A |
| Terminated | Bedside Evaluation of Edema NCT03296085 | Geisinger Clinic | — |
| Unknown | Different Endodontic Treatment Techniques in Postoperative Symptoms, Apical Repair, Longevity of Rehabilitatio NCT03704857 | Universidade Federal Fluminense | N/A |
| Completed | Effect of Body Weight Loading on Urinary Electrolyte Excretion NCT03213717 | Göteborg University | N/A |
| Unknown | Impact of Preemptive Intravenous Ibuprofen on Postoperative Edema and Trismus in the Third Molar Teeth NCT03170713 | Erzincan University | N/A |
| Unknown | Leukocyte- and Platelet Rich Fibrin (L-PRF) Application in Impacted Mandibular Third Molar Removal Surgery NCT03357484 | Lithuanian University of Health Sciences | N/A |
| Completed | Acute Effects of Interferential Current on Edema, Pain and Muscle Strength in Patients With Distal Radius Frac NCT03438864 | Ege University | N/A |
| Active Not Recruiting | Carboplatin and Paclitaxel With or Without Panitumumab in Treating Patients With Invasive Triple Negative Brea NCT02876107 | M.D. Anderson Cancer Center | Phase 2 |
| Completed | Acupuncture on Anxiety and Inflammatory Events Following Surgery of Mandibular Third Molars NCT03545022 | Federal University of the Valleys of Jequitinhonha and Mucuri | N/A |
| Completed | Prospective Evaluation of a Surgical Solution for Breast Cancer-Associated Lymphedema NCT02734979 | Stanford University | N/A |
| Completed | A Single-Center, Clinical Study to Evaluate the Safety of a New Personal Lubricant in Healthy Female Subjects NCT02737852 | Church & Dwight Company, Inc. | N/A |
| Completed | A Clinical Study to Evaluate the Safety of a Personal Lubricant in Healthy Female Subjects NCT02737592 | Church & Dwight Company, Inc. | N/A |
| Completed | Human Repeat Insult Patch Test to Evaluate Personal Lubricants NCT02737631 | Church & Dwight Company, Inc. | N/A |
| Completed | Breast Edema Compression Vest NCT02627976 | UMC Utrecht | N/A |
| Completed | Evaluation of Two Pharmacological Protocols for Pre-emptive Analgesia in Impacted Third Molar Surgery NCT02665533 | Federal University of the Valleys of Jequitinhonha and Mucuri | N/A |
| Unknown | Microcurrent Stimulation Reduces Post-Operative Swelling and Healing Time Following Knee Replacement Surgery NCT02623660 | Bioelectric Research Corporation | N/A |
| Completed | Relation Between the Increase of Peripheral Edema by Fluid Therapy and the Decrease in Microcirculatory Vessel NCT02661269 | Frisius Medisch Centrum | — |
| Completed | Impact of Negative Pressure Wound Therapy on Free Muscle Flaps NCT02526342 | Ulf Dornseifer, MD | N/A |
| Terminated | Oedematous Lower Limb Subcutaneous Drainage in Palliative Care NCT02473744 | University Hospital, Limoges | N/A |
| Active Not Recruiting | Pembrolizumab in Treating Patients With Stage IV Metastatic or Recurrent Inflammatory Breast Cancer or Triple- NCT02411656 | M.D. Anderson Cancer Center | Phase 2 |
| Completed | The Effect of Neuromuscular Stimulation on Post-Transplant Leg Edema NCT01860820 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Completed | Role of Acetazolamide and Hydrochlorothiazide Followed by Furosemide in Treating Nephrotic Edema NCT02427880 | Shiraz University of Medical Sciences | Phase 4 |
| Completed | The Effects of Manual Lymphatic Drainage and Kinesiotaping on Lower Extremity Edema NCT04164927 | Hacettepe University | N/A |
| Completed | A Single-Center, Clinical Study to Evaluate the Safety of a Non-Fragranced Personal Lubricant in Healthy Femal NCT02320227 | Church & Dwight Company, Inc. | N/A |
| Completed | A Single-Center, Clinical Study to Evaluate the Safety of a Fragranced Personal Lubricant in Healthy Female Su NCT02320214 | Church & Dwight Company, Inc. | N/A |
| Completed | Repeated Insult Patch Test of Personal Lubricants NCT02297841 | Church & Dwight Company, Inc. | N/A |
| Completed | Furosemide and Albumin for Diuresis of Edema: A Pilot Randomized Controlled Trial NCT02055872 | Hamilton Health Sciences Corporation | Phase 3 |
| Completed | The Effect of Postrhinoplasty Taping on Postoperative Edema and Nasal Draping NCT02626585 | Bezmialem Vakif University | N/A |
| Unknown | 2%-Mepivacaine With Two Different Vasoconstrictors Solutions in Third Molar Surgery a Comparative Study NCT02603198 | University of Sao Paulo | N/A |
| Unknown | Low Laser Light Therapy After Impacted Third Molar Removal NCT02602431 | University of Sao Paulo | N/A |
| Unknown | Validation of a New Method of Limb Volumetry NCT01574911 | University Hospital, Montpellier | — |
| Completed | Mild Compression Sock for Control of Lower Extremity Edema in Individuals With Diabetes NCT01529385 | Rosalind Franklin University of Medicine and Science | N/A |
| Completed | Safety and Feasibility of Prima-Temp Thermometer Patch NCT01587014 | Poudre Valley Health System | — |
| Completed | The Efficacy and Safety of Hypertonic Saline in Cardiac Surgery Patients. NCT01675453 | Meshalkin Research Institute of Pathology of Circulation | Phase 2 |
| Unknown | Effects of Hyperbaric Oxygen Therapy on Surgical Wound Healing NCT01605110 | Restorix Research Institute, LLLP | N/A |
| Completed | Body Composition and Serum Biochemistry After Intravenous Infusion or Oral Intake of Saline in Healthy Volunte NCT01539798 | Federal University of Mato Grosso | N/A |
| Completed | Effect of Dexamethasone and Methylprednisolone on Pain, Swelling and Trismus After Third Molar Surgery NCT01603498 | Federal University of the Valleys of Jequitinhonha and Mucuri | N/A |
| Unknown | Safety and Efficacy Study of Gamaline+Hipericin in PMS NCT01283568 | Phytopharm Consulting Brazil | — |
| Completed | Topical Treatment of Under Eye Dark Circles and Swelling NCT01172522 | The Connecticut Sinus Center, PC | Phase 2 |
| Terminated | Use of Compression Glove to Prevent Complications After Distal Radius Fractures: a Randomized Controlled Trial NCT01118715 | J&M Shuler | N/A |
| Unknown | Effect of Normatec Pump for Relief of Leg Edema NCT01112150 | Hillel Yaffe Medical Center | N/A |
| Completed | Xerecept Intravenous Dose Escalation in Japanese and Caucasian Volunteers NCT00820092 | Celtic Pharma Development Services | Phase 1 |
| Unknown | Etodalac, Etoricoxib and Dexamethasone for Prevention of Pain ,Swelling and Trismus Following Third Molar Surg NCT00793052 | Tel-Aviv Sourasky Medical Center | N/A |
| Completed | Reducing Edema Following Refractive Surgery NCT00691847 | FORSIGHT Vision3 | — |
| Completed | Lower Leg Edema Evaluation After Total Knee Arthroplasty Using Bioimpedance NCT00627770 | Haute Ecole de Santé Vaud | N/A |
| Completed | Effective Treatment of Posttraumatic and Postoperative Edema NCT01389089 | Luzerner Kantonsspital | N/A |
| Completed | Measuring Hand Edema in Burn Patients NCT00137228 | United States Army Institute of Surgical Research | N/A |
| Completed | Compression Device Safety Study on Edema NCT00732719 | ConvaTec Inc. | Phase 2 |
| Completed | A Dose-finding Study of OPC-41061 in Treatment of Cardiac Edema (Congestive Heart Failure) NCT00234104 | Otsuka Pharmaceutical Co., Ltd. | Phase 2 |
| Completed | Bioequivalency Study of Torsemide Tablets Under Fasting Conditions NCT00602303 | Roxane Laboratories | N/A |
| Completed | Bioequivalency Study of Torsemide Tablets Under Fed Conditions NCT00602615 | Roxane Laboratories | N/A |
| Completed | Trial Assessing the Effect of Preoperative Furosemide on Intraoperative Blood Pressure NCT00115726 | University of Calgary | Phase 4 |