NCT05466604

Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema

Comparison of the Effects of Hyaluronidase and Dexamethasone on Reduction of Postoperative Edema in Impacted Wisdom Teeth Surgery

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Hacettepe University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

The present study is designed to reveal effectiveness of hyaluronidase and dexamethasone on reduction of postoperative edema, pain, trismus, and infection. For this purpose, 60 participants with symmetrical mandibular wisdom teeth enrolled the present study. All measurements and evaluations were performed before and 1, 2, 3, and 7 days later the operation.

Conditions

• Edema
• Pain
• Trismus
• Infection, Surgical Site

Interventions

Type	Name	Description
DRUG	Hyaluronidase Injection mesomedica	injection of 150 IU hyaluronidase to perioperative region, submucosally.
DRUG	Dexamethasone dekort	injection of 8 mg dexamethasone to perioperative region, submucosally.

Timeline

• Start date: 2019-12-01
• Primary completion: 2022-06-30
• Completion: 2022-06-30
• First posted: 2022-07-20
• Last updated: 2022-07-20

Locations

2 sites across 2 countries: Cyprus, Turkey (Türkiye)