NCT03967717

Correlation of Clinical and Laboratory Findings and Diuretic Efficacy in Patients With Edematous States in the Emergency Department

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 102 (actual)
• Sponsor: University of Cologne · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is the characterization of parameters from medical history, physical examination and diagnostics, which correlate with and could be used to predict diuretic efficacy.

Detailed description

This prospective observational study is conducted to identify and further isolate possible predictors for the efficacy of diuretics and to identify potential new predictors. The study also observes if specific diuretic regimes (e.g. combination of loop diuretics and distal effective diuretics for sequential nephron blockade) have a greater diuretic effect. This is not yet proved. The data of the study shall to help to determine criteria, allowing to choose an effective diuretic regime in different patient cohorts already at the beginning of therapy and to identify patients at high risk.

Conditions

• Edema

Interventions

Type	Name	Description
OTHER	Characterization of parameters of medical history, examination and diagnostics.	Patients receive standard of care diuretics. The study only collects data to characterize parameters of medical history, examination and diagnostics.

Timeline

• Start date: 2019-06-28
• Primary completion: 2022-03-18
• Completion: 2022-04-04
• First posted: 2019-05-30
• Last updated: 2023-11-29

Locations

1 site across 1 country: Germany