Dry Eye Syndrome

138 registered clinical trials studyying Dry Eye Syndrome — 6 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Effects of AffronEye®/ Crocuvis+® on Dry Eye Syndrome NCT06240364	University of Alicante	N/A
Recruiting	Autologous Serum Eye Drops in Dry Eye Syndrome NCT07295691	The General Authority for Teaching Hospitals and Institutes	N/A
Recruiting	A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusio NCT06977724	AbbVie	Phase 1
Active Not Recruiting	Comparing Effect of Hylorunic Acid and Lipid-coated Carbomer Gel on Dry Eyes After Phacoemulsification in DP NCT06913556	Superior University	N/A
Active Not Recruiting	Efficacy of Warm Compress Therapy in Enhancing Tear Film Quality and Reducing Postoperative DES NCT06914232	Superior University	N/A
Completed	Performance and Safety of T2769 Versus Hylo-Forte® in the Treatment of Moderate to Severe Dry Eye Syndrome. NCT06375499	Laboratoires Thea	N/A
Not Yet Recruiting	Exosome-miRNA and Transcriptome Profiling of Dry Eye Syndrome and Sjogren's Syndrome NCT06475027	Taipei Veterans General Hospital, Taiwan	—
Completed	A Study to Assess Symptom Relief and Product Tolerability of ABBV-444 Drops in Adult Participants NCT05878067	AbbVie	Phase 3
Terminated	Evaluation of Performance and Safety of Carbopol 980 NF 0.2%- Based Medical Device in the Management of Patien NCT06190028	Fidia Farmaceutici s.p.a.	N/A
Completed	VGH-DESJS-1 in Ocular and Oral Dryness Symptoms of Dry Eye Syndrome and Sjögren's Syndrome NCT05656196	Taipei Veterans General Hospital, Taiwan	N/A
Unknown	Observational Study on the Improvement of Dry Eye Syndrome, Treatment Satisfaction, and Intraocular Tolerance NCT06172530	Hanlim Pharm. Co., Ltd.	—
Completed	Effect of an Educational Program on Health-related Outcomes of Patients With Dry Eye Syndrome NCT06288945	Alexandria University	N/A
Completed	Clinical Trial to Assess the Effectiveness of I+Med's DayDrop Advanced Ophthalmic Drop NCT06732830	i+Med S.Coop.	N/A
Unknown	To Evaluate the Short-term and Long Term Efficacy of Acupuncture in Ocular and Oral Dryness Symptoms of Dry Ey NCT04877483	Taipei Veterans General Hospital, Taiwan	N/A
Not Yet Recruiting	Dry Eye Syndrome, Healthy Control, Sjögren's Syndrome and Other Inflammation Disease in Taiwan Biobank NCT03938207	Taipei Veterans General Hospital, Taiwan	—
Completed	Probiotic in Dry Eye Syndromes NCT04938908	Shiraz University of Medical Sciences	Phase 2
Unknown	Treatment of Dry Eye Disease Using Pro-ocular™ - A Proof of Concept, Safety, and Efficacy Study NCT04884217	PharmaDax Inc.	Phase 2
Unknown	Objective Measurement With TCM Pattern for AIDDES NCT04747288	Taipei Veterans General Hospital, Taiwan	—
Unknown	Comprehensive Study on Dry Eye and Ocular Surface Disease Prior and After Cataract Surgery NCT04711642	Fundación Oftalmológica Los Andes	Phase 3
Unknown	Evaluating the Efficacy and Safety of TJO-087 in Moderate to Severe Dry Eye Disease Patients NCT05245604	Taejoon Pharmaceutical Co., Ltd.	Phase 3
Completed	A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye Disease NCT04030962	AbbVie	Phase 1 / Phase 2
Recruiting	Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface NCT04198740	Centre hospitalier de l'Université de Montréal (CHUM)	—
Completed	Safety and Efficacy of BRM421 for Dry Eye Syndrome Treatment NCT04343287	BRIM Biotechnology Inc.	Phase 2 / Phase 3
Completed	Vehicle-Controlled Study of SkQ1 as Treatment for Dry-eye Syndrome NCT04206020	Mitotech, SA	Phase 3
Completed	Dose Ranging Study to Assess the Efficacy and Safety of Voclosporin Ophthalmic Solution in Subjects With Dry E NCT04147650	Aurinia Pharmaceuticals Inc.	Phase 2 / Phase 3
Completed	Safety, PK and Efficacy Study of SJP-0132 in Subjects With Dry Eye Disease NCT04139122	Senju Pharmaceutical Co., Ltd.	Phase 1 / Phase 2
Unknown	Heidelberg In Vivo Confocal Microscopy to Evaluate the Ocular Surface Disorders of Healthy and Diseased Indivi NCT04025801	National Taiwan University Hospital	—
Terminated	To Demonstrate the Non-inferiority of Eyestil Protection® Compared to Vismed® in Terms of Clinical Performance NCT03803722	SIFI SpA	N/A
Completed	A Study to Evaluate Safety and Efficacy of rhNGF Eye Solution vs Vehicle in Patients With Moderate to Severe D NCT03982368	Dompé Farmaceutici S.p.A	Phase 2
Completed	Dry Eye Syndrome Description During Cataract Surgery, With Multimodal Analysis of the Ocular Surface NCT03923244	University Hospital, Clermont-Ferrand	N/A
Withdrawn	Objective Measurement Methods for Autoimmune Disease and Dry Eye Syndrome NCT03937271	Taipei Veterans General Hospital, Taiwan	—
Completed	Study of TOP1630 for Dry Eye Syndrome NCT03833388	Topivert Pharma Ltd	Phase 2 / Phase 3
Unknown	Assessment of the Mu-Drop System for Serum Eye Drops NCT03539159	Sanquin Research & Blood Bank Divisions	N/A
Completed	Study of SkQ1 as Treatment for Dry-eye Syndrome NCT03764735	Mitotech, SA	Phase 3
Completed	Efficacy, Safety of T2769 in Dry Eye Disease NCT03830359	Laboratoires Thea	N/A
Unknown	DRy Eye Outcome and Prescription Study NCT03652415	Guy's and St Thomas' NHS Foundation Trust	—
Completed	The Effect of Manuka Eye Drops on Tear Film Properties NCT03622619	The University of New South Wales	N/A
Completed	Piiloset Trehalose Emulsion Eye Drop Study in Moderate or Severe Dry Eye NCT03569202	Kuopio University Hospital	N/A
Unknown	Functional MRI Study of Cortical Modifications to Light Stimulation in Patients With Photophobia NCT03464357	University Hospital, Toulouse	N/A
Completed	Comparison of Ocular Surface Features in Patients With Diabetes and Dry Eye Syndrome NCT03576300	Peking University Third Hospital	—
Unknown	Corneal Tear Film Imaging of the Cornea Before and After Restasis Therapy NCT03403023	Meir Medical Center	N/A
Completed	Efficacy and Safety of HU007 Eye Drops in Patients With Dry Eye Syndrome NCT03461575	Huons Co., Ltd.	Phase 3
Completed	Effectiveness of Intense Pulsed Light for Improving Dry Eye Syndrome NCT03396913	Lumenis Be Ltd.	N/A
Completed	A Multi-Center, Randomized, Double Masked, Parallel-Group, Vehicle-Controlled, Clinical Study to Assess the Sa NCT03404115	Aldeyra Therapeutics, Inc.	Phase 2
Completed	Clinical Study to Investigate the Efficacy and Safety of Orally Administered SA001 in Patients With Dry Eye Sy NCT03723798	Samjin Pharmaceutical Co., Ltd.	Phase 2
Completed	Allogeneic Versus Autologous Serum Eye Drops NCT03085290	Sanquin Research & Blood Bank Divisions	N/A
Unknown	Assessing the Safety and Efficacy of AVX-012 in Subjects With Mild-to-moderate Dry Eye Syndrome NCT03162094	Avizorex Pharma, S.L.	Phase 1 / Phase 2
Completed	Safety and Efficacy of TOP1630 for Dry Eye Syndrome NCT03088605	ORA, Inc.	Phase 2
Completed	Safety and Efficacy of BRM421 for Dry Eye Syndrome NCT03066219	BRIM Biotechnology Inc.	Phase 2
Completed	Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome : ARISE-2 NCT02974907	ReGenTree, LLC	Phase 3
Completed	Efficacy Comparison of Two Kinds of Treatment in Treating Dry Eye Caused by Meibomian Gland Dysfunction NCT02958514	Peking University Third Hospital	N/A
Completed	Efficacy and Safety of the Ophthalmic Solution PRO-087 Versus Systane ® Ultra and Ultra Preservative Free (087 NCT03223909	Laboratorios Sophia S.A de C.V.	Phase 4
Completed	Influencing Factors on Dry Eye Syndrome and Ocular Surface Disease NCT03364322	Hallym University Kangnam Sacred Heart Hospital	—
Unknown	Optical Coherence Tomography of Ocular Structures in Epiphora and Dry Eye Syndrome. NCT02849093	Bedford Hospital NHS Trust	—
Completed	Acute Tear Production Following Single Use of the Oculeve Intranasal Neurostimulator NCT02798289	Oculeve, Inc.	N/A
Completed	Cross-linked Hyaluronic Acid and Coenzyme Q10 in the Treatment of Dry Eye NCT03074344	Azienda Ospedaliera Universitaria Policlinico "G. Martino"	N/A
Completed	Exploring Immune Cell Signatures in Autoimmunity and Dry Eye Syndrome NCT02715323	Singapore National Eye Centre	—
Unknown	Study to Evaluate the Efficacy and Safety of CKD-350 NCT02777723	Chong Kun Dang Pharmaceutical	Phase 3
Completed	Efficacy and Safety Study of HU00701/HU007 Eye Drops in Patients With Dry Eye Syndrome NCT02917512	Huons Co., Ltd.	Phase 2
Completed	A Study to Evaluate the Safety and Effectiveness of Oculeve Intranasal Lacrimal Neurostimulator in Participant NCT02680158	Oculeve, Inc.	N/A
Unknown	Comparing the Quality of Topical Autologous Serum in Different Etiologies of Dry Eye Syndrome NCT02774707	National Taiwan University Hospital	—
Completed	Evaluation of Factors Affecting the Tear-film Lipid Layer Thickness NCT02645045	Yonsei University	—
Completed	The Comparison of 50% AS Versus PFAT+ 0.05 % COE in Severe Dry Eye Syndrome NCT03666884	Seref istek	Phase 4
Completed	Evaluation of Tear Osmolarity Over Time With Sustained Use of Thera Tears Lubricating Drops NCT02758327	Koffler Vision Group	Phase 4
Completed	A Retrospective Analysis of Restasis® Benefits in Dry Eye Contact Lens Patients NCT02522312	Hazleton Eye Specialists	—
Completed	Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-1 NCT02597803	ReGenTree, LLC	Phase 2 / Phase 3
Completed	Tolerability, Safety and Efficacy of Lubricin Versus Sodium Hyaluronate Eye Drops in Patients With Moderate Dr NCT02507934	Dompé Farmaceutici S.p.A	N/A
Completed	Clinical Evaluation Following Use of SYSTANE® ULTRA in the Management of Dry Eye NCT02446015	Alcon Research	N/A
Completed	Dose-finding Study to Assess the Safety and Effect of SYL1001 in Patients With Ocular Pain NCT02455999	Sylentis, S.A.	Phase 2
Completed	Tolerability, Safety and Efficacy of Lubricin vs Sodium Hyaluronate Eye Drops in Subjects With Moderate Dry Ey NCT02510235	Dompé Farmaceutici S.p.A	N/A
Completed	The Effect of Eyelid Surgery on Dry Eye - a Prospective Study NCT02376556	Sheba Medical Center	—
Completed	Study of ST266 Eye Drops in Treating Dry Eye NCT02369861	Noveome Biotherapeutics, formerly Stemnion	Phase 1
Terminated	Comparison of the Efficacy and Safety of T2762 Versus Optive® in the Treatment of Moderate to Severe Dry Eye S NCT02617095	Laboratoires Thea	N/A
Completed	Point of Care Testing of Inflammatory Markers in Tears NCT02315079	University of Florida	—
Withdrawn	Assessment of Tear Film Thickness by Optical Coherence Tomography in Healthy Subjects and Subjects With Dry Ey NCT01753596	Medical University of Vienna	Phase 3
Completed	Phase 2 Study With Cis-UCA Ophthalmic Solutions in Subjects With Dry Eye NCT02326090	Herantis Pharma Plc.	Phase 2
Completed	Changes in Tear Osmolarity Over Time With Sustained Use of TheraTears NCT02100787	Jenkins Eye Care	N/A
Withdrawn	Pilot Study to Clinical Evaluate Device Prototypes in Dry Eye Patients NCT01957670	Lacrima Medical LTD	N/A
Completed	Safety and Efficacy of rhNGF Eye Drops at Different Doses in Patients With Dry Eye NCT02101281	Dompé Farmaceutici S.p.A	Phase 2
Completed	Efficacy and Safety of T2762 and Vismed® in Dry Eye Syndrome NCT02023268	Laboratoires Thea	Phase 3
Completed	Safety and Efficacy of PG101 for Dry Eye Syndrome NCT02078661	Rhodes Pharmaceuticals, L.P.	Phase 1 / Phase 2
Completed	Effect of Olixia Pure® Eye Drops on Tear Film Thickness in Healthy Subjects NCT01970917	Medical University of Vienna	Phase 4
Completed	IPL and Meibomian Gland Expression to Treat Ocular Rosacea Ocular GVHD NCT02066051	Mayo Clinic	N/A
Completed	Clinical Evaluation of Systane® ULTRA Compared to OPTIVE® in Ocular Surface Staining NCT01863368	Alcon Research	N/A
Completed	Investigation on Medical Management of Dry Eye Patients NCT01942226	National Cheng Kung University	—
Completed	The Effect of Intravenous Glucocorticoids on the Tearfilm in Eyes With Thyroid-associated Ophthalmopathy NCT01579539	Medical University of Vienna	Phase 3
Withdrawn	Efficacy of Pulsed Light Therapy for Meibomian Gland Dysfunction and Dry Eye Syndrome NCT01917539	University of Miami	N/A
Completed	Efficacy and Safety of HE10 for Dry Eye Syndrome NCT02492412	Huons Co., Ltd.	Phase 3
Completed	Influence of Lachrymal Substitutes on Tear Film Thickness in Patients With Moderate Dry Eye Syndrome NCT01864330	Medical University of Vienna	Phase 4
Completed	Treatment of Meibomian Gland Dysfunction Prior to Cataract Surgery NCT01808560	TearScience, Inc.	N/A
Completed	SYSTANE® BALANCE Symptoms (OSDI) & Inflammatory Biomarkers NCT01733732	Alcon Research	N/A
Completed	SYSTANE® Family - Meibomian Deficiency NCT01733745	Alcon Research	N/A
Completed	Effects of Dry Eye Treatments on the Ocular Surface NCT01797822	Baylor College of Medicine	Phase 4
Completed	Evaluation of SYSTANE® BALANCE in Dry Eye Subjects With Lipid Deficiency NCT01688726	Alcon Research	N/A
Completed	A Multi-Center Study Subjects With Dry Eye Syndrome NCT01745887	Eleven Biotherapeutics	Phase 1
Completed	Pilot Study to Evaluate SYL1001 Safety and Effect in Patients With Ocular Pain NCT01776658	Sylentis, S.A.	Phase 1 / Phase 2
Completed	Phase 2 Study to Evaluation the Safety and Efficacy of Orally Administered KL7016 in Patients With Dry Eye Syn NCT02092207	Yungjin Pharm. Co., Ltd.	Phase 2
Completed	Evaluation of the Corneal Residence Time of Chitosan-N-acetylcysteine Eye Drops in Patients With Dry Eye Syndr NCT01753752	Gerhard Garhofer	Phase 2
Completed	A Study of RX-10045 in the Treatment of Dry Eye Disease NCT01675570	C.T. Development America, Inc.	Phase 2
Completed	Efficacy and Safety of Rebamipide in Subjects With Dry Eye Syndrome NCT01632137	Kubota Vision Inc.	Phase 3
Completed	Clinical Evaluation of a Daily Disposable Contact Lens in Symptomatic Weekly/Monthly Lens Wearers NCT01614600	Alcon Research	N/A
Completed	Phase II Study of DA-6034 Eye Drops in Dry Eye Syndrome NCT01670357	Dong-A ST Co., Ltd.	Phase 2
Unknown	Oral Nutrition Impact on Tear Film NCT01561040	Eye and Vision Technologies and Research Institute	Phase 4
Completed	Efficacy and Safety of PRO-148 Ophthalmic Solution Versus SYSTANE® in the Treatment of Patients With Dry Eye S NCT01541891	Laboratorios Sophia S.A de C.V.	Phase 2
Completed	Correlation of Different Signs for Assessment of Dry Eye Syndrome NCT01753687	Medical University of Vienna	N/A
Completed	Safety and Efficacy of Thymosin Beta 4 Ophthalmic Solution in Patients With Dry Eye NCT01387347	ReGenTree, LLC	Phase 2
Completed	Sodium Hyaluronate Ophthalmic Solution, 0.18% for Treatment of Dry Eye Syndrome NCT01382225	Alcon Research	Phase 3
Completed	Assessment of Safety and Tolerability of Chitosan-N-acetylcysteine Eye Drops in Subjects While Wearing Contact NCT01747616	Medical University of Vienna	Phase 1
Completed	Evaluation of the Effect of Repeated Usage on the Tear Film Characteristics of an Investigational Eye Drop in NCT01339936	Optometric Technology Group Ltd	Phase 2 / Phase 3
Completed	In Vivo Measurement of Corneal Epithelial Changes in Dry Eye Patients NCT01483989	Alcon Research	N/A
Completed	Reproducibility of Tearfilm Osmolarity Measurements Using TearLab® in Patients With Dry Eye Syndrome and Healt NCT01744457	Medical University of Vienna	N/A
Completed	Residence Time Evaluation of Systane Ultra Lubricant Eye Drops vs. Hialid and Saline NCT01252121	Alcon Research	N/A
Completed	Evaluating Safety and Efficacy of FID 112903 Post Discontinuation of Long-term Use of RESTASIS® (Cyclosporine NCT01198782	Alcon Research	Phase 4
Completed	A Dose Ranging Study to Evaluate Safety and Efficacy of Bromfenac Ophthalmic Solution in Dry Eye Disease NCT01212471	Bausch & Lomb Incorporated	Phase 3
Completed	An Open-Label, Single-Center Study Evaluating the Effect of Systane Balance on Video Ocular Protection Index ( NCT01223040	Alcon Research	N/A
Terminated	Non-invasive Ocular Surface Measurements Before and After Interventions NCT01228929	University of Rochester	N/A
Completed	Study to Assess the Safety and Efficacy of BOL-303242-X Ophthalmic Suspension in Dry Eye Syndrome NCT01163643	Bausch & Lomb Incorporated	Phase 2
Completed	Oral Omega-3 Fatty Acids in the Treatment of Dry Eye Syndrome NCT01107964	Milton S. Hershey Medical Center	N/A
Completed	Treatment of Dry Eye Using 0.03% Tacrolimus Eye Drops NCT01850979	University of Sao Paulo General Hospital	Phase 4
Completed	Safety and Efficacy of Two Artificial Tears in Dry Eye Subjects NCT01010282	Allergan	N/A
Completed	The Effect of a New Emulsion in Dry Eye Patients on Tear Layer Aberrometry, Contrast Sensitivity, and Reading NCT01013077	Southern California College of Optometry at Marshall B. Ketchum University	N/A
Completed	Safety and Tolerability of Artificial Tears in Dry Eye Subjects NCT00932477	Allergan	N/A
Withdrawn	Tears Substitutions and Their Effects on Higher Order Aberrometery NCT00812721	Gina Rogers	N/A
Completed	Systane Clinical Experience Study NCT00818909	Alcon Research	Phase 4
Completed	Safety and Efficacy Study of RX-10045 on the Signs and Symptoms of Dry Eye NCT00799552	Resolvyx Pharmaceuticals, Inc	Phase 2
Completed	Safety and Efficacy Study of Iontophoresis and Dexamethasone Phosphate to Treat Dry Eye NCT00765804	Eyegate Pharmaceuticals, Inc.	Phase 2
Completed	Phase I Study to Evaluate the Tolerability of Eye Drop DA-6034 in Healthy Volunteers NCT01162954	Dong-A ST Co., Ltd.	Phase 1
Completed	CXCL9, CXCL10, CXCL11, and CXCR3 in Dry Eye Syndrome NCT00991679	Chonnam National University Hospital	—
Completed	Evaluation of Blink Tears and Systane Concomitant With Restasis for the Treatment of Dry Eye Symptoms NCT00565669	Medical University of South Carolina	N/A
Completed	Safety and Efficacy of an Artificial Tear for the Treatment of Dry Eye NCT00514852	Allergan	N/A
Completed	Evaluate the Safety and Efficacy of a New Artificial Tear for Use After LASIK Surgery NCT00544713	Allergan	N/A
Completed	Study to Assess the Safety and Patients' Satisfaction of Tears Again* in the Treatment of Dry Eye Symptoms NCT00535054	Trima, Israel Pharmaceutical Products	N/A
Completed	Eye Drop Use in Glaucoma Patients Through Patient Surveys and Video Observations NCT00522600	Robin, Alan L., M.D.	—
Withdrawn	A Prospective Clinical Study Assessing the Effects of Tetracycline Antibiotic on Tear Film and Tear Lipid Comp NCT00355459	University of Texas Southwestern Medical Center	N/A
Completed	A Placebo Controlled Double Masked Clinical Assessment Study of Essential Fatty Acid Supplement and Its Effect NCT00344721	University of Texas Southwestern Medical Center	N/A
Completed	Lid Margin And Conjunctival Microbial Flora Following Punctum Occlusion NCT00735865	Lahey Clinic	N/A
Completed	Efficacy Comparative Study Between Tears Again®, Opticol® and Optive® NCT00893243	Hospital de Sao Sebastiao	—
Completed	Comparison of Autologous Serum and Umbilical Cord Serum Eyedrops for Dry Eye Syndrome NCT00442273	Chonnam National University Hospital	N/A