NCT00442273

Comparison of Autologous Serum and Umbilical Cord Serum Eyedrops for Dry Eye Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: —
• Sponsor: Chonnam National University Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 61 Years
• Healthy volunteers: —

Summary

To compare the therapeutic effect between autologous serum and umbilical cord serum eyedrops in the treatment of severe dry eye syndrome.

Detailed description

Ninety-two eyes of 48 patients with severe dry eye syndrome (34 eyes of 17 patients with Sjögren's syndrome and 58 eyes of 31 patients with non-Sjögren's syndrome) were treated with either 20% autologous serum (41 eyes of 21 patients) or umbilical cord serum eyedrops (51 eyes of 27 patients). Symptom scoring, corneal sensitivity test, tear film break-up time (BUT), Schirmer test, tear clearance rate (TCR), corneal fluorescein staining, and conjunctival impression cytology were performed before and 1 month and 2 months after treatment.

Conditions

• Dry Eye Syndrome

Interventions

Type	Name	Description
DRUG	Umbilical cord serum eyedrops
DRUG	Autologous serum eyedrops

Timeline

• First posted: 2007-03-01
• Last updated: 2007-03-01

Locations

1 site across 1 country: South Korea