NCT03622619

The Effect of Manuka Eye Drops on Tear Film Properties

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 46 (actual)
• Sponsor: The University of New South Wales · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Traditionally, Manuka honey has been used to combat against bacteria and reduce inflammation (the body's way of reacting to infection, irritation or other injury). Due to the inflammatory nature of dry eye, Manuka eye drops show promise as a treatment for dry eye disease. The aim of this research is to compare the effects of two over the counter eye drops that are used to treat dry eye conditions over a one month period.

Detailed description

The aim of the present study is to conduct a randomised clinical trial to compare the effect on tear film properties and dry eye signs and symptoms of Optimel Manuka eye drops compared to Systane Ultra, a widely available over the counter aqueous tear supplement as a control eye drop. This investigation will involve a minimum of 40 participants who have dry eye, who are randomly put into two groups receiving either Optimel Manuka drops or Systane Ultra used three times daily for one month. Both of these products are commercially available in Australia. Results from this study will inform practitioners as to the potential benefits of Manuka eye drops on tear film characteristics and signs and symptoms of dry eye.

Conditions

• Dry Eye Syndrome

Interventions

Type	Name	Description
OTHER	Optimel Antibacterial Manuka+ Dry Eye Drops	Leptospermum sp Honey 165mg/g
OTHER	Systane Ultra Lubricating Eye Drops	Polyethylene glycol 400 0.4% and propylene glycol 0.3%

Timeline

• Start date: 2018-08-13
• Primary completion: 2018-10-30
• Completion: 2018-10-30
• First posted: 2018-08-09
• Last updated: 2021-05-18
• Results posted: 2021-01-27

Locations

1 site across 1 country: Australia