NCT01753687

Correlation of Different Signs for Assessment of Dry Eye Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Medical University of Vienna · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Dry eye syndrome (DES) is a highly prevalent ocular condition inducing an inflammatory response of the ocular surface. Common symptoms include ocular discomfort, visual impairment and instability of the tear film with potential damage to the ocular surface. The rationale of the present study is to compare signs as assessed with new methods such as measurement of tear film thickness, tear film osmolarity and scattering of the tear film with well established methods for assessment of the severity of DES (Break up time, staining of the cornea with fluorescein). Additionally, impression cytology and determination of tear cytokines/chemokines will be performed to obtain information about inflammatory processes on the ocular surface.

Conditions

• Dry Eye Syndrome

Interventions

Type	Name	Description
OTHER	Ocular scattering of the tear film
OTHER	Optical Coherence Tomography (OCT)	Tear film thickness as measured with OCT
OTHER	Measurement of tear film osmolarity

Timeline

• Start date: 2011-09-01
• Primary completion: 2013-07-01
• Completion: 2013-09-01
• First posted: 2012-12-20
• Last updated: 2013-11-27

Locations

1 site across 1 country: Austria