| Not Yet Recruiting | Evaluation of MTX-439 in Healthy Adults and Adults With Diabetic Kidney Disease NCT07473323 | Mediar Therapeutics | Phase 1 |
| Not Yet Recruiting | Spironolactone Alternate Dosing vs Finerenone in Elevated Potassium - K Safety Study NCT07523867 | Hospital de Messejana Dr. Carlos Alberto Studart Gomes | Phase 4 |
| Recruiting | Improving Kidney Care in Type 2 Diabetes: A Study of Pharmacist Prescribing Versus Usual Care NCT07169422 | Nova Scotia Health Authority | N/A |
| Not Yet Recruiting | Gut Microbiota and Serum Metabolites as Predictors of Glycemic Variability and Outcomes in Diabetic Kidney Dis NCT07352436 | Eighth Affiliated Hospital, Sun Yat-sen University | — |
| Enrolling By Invitation | Immune System in Diabetic Kidney Disease NCT07292493 | University Medical Centre Ljubljana | — |
| Recruiting | Formoterol in Diabetes NCT07022418 | Medical University of South Carolina | Phase 2 |
| Not Yet Recruiting | Role of Finerenone in African American Veterans With Diabetic Kidney Disease NCT07155694 | Washington D.C. Veterans Affairs Medical Center | Phase 4 |
| Not Yet Recruiting | Oxygen Therapy in Diabetic Kidney Disease NCT06959485 | Assiut University | N/A |
| Withdrawn | P2a Open Label Study to Evaluate 2-HPβCD in Subjects With Diabetic Kidney Disease NCT06489340 | ZyVersa Therapeutics, Inc. | Phase 2 |
| Not Yet Recruiting | Efficacy and Safety of LC-Z300-01 on Proteinuria in Diabetic Patients NCT06686758 | Shanghai Changzheng Hospital | N/A |
| Recruiting | A Study to Evaluate the Safety, Tolerability, PK and PD of AP303 in DKD Patients NCT06666283 | Alebund Pharmaceuticals | Phase 1 |
| Recruiting | Effect of Acute Hypoxia on Renal Hemodynamic in Healthy Volunteers, Patients With Diabetes and Patients With D NCT06846034 | Poitiers University Hospital | N/A |
| Active Not Recruiting | "Residual Kidney Function and Oxidative Stress in Incremental vs Standard Peritoneal Dialysis (2 Mexican Cente NCT07338435 | Instituto Mexicano del Seguro Social | N/A |
| Not Yet Recruiting | Revealing Engagement Dynamics Among Diabetic Kidney Disease Patients NCT06101901 | Power Life Sciences Inc. | — |
| Recruiting | The Evaluation of the Drug R3R01 for the Excretion of Protein in the Urine in Patients With Diabetic Kidney Di NCT06600412 | River 3 Renal Corp. | Phase 2 |
| Not Yet Recruiting | Metabolic Phenotypes of Obesity and Diabetic Kidney Disease in Patients with Type 2 Diabetes Mellitus NCT06591104 | Assiut University | — |
| Not Yet Recruiting | Clinical Trial of Keluoxin Capsules in the Treatment of Diabetic Kidney Disease with Diabetic Retinopathy NCT06660940 | Chinese PLA General Hospital | Phase 4 |
| Unknown | Evaluate the Role of Soleus Muscle Exercise in Glycaemic Control in Diabetic Kidney Disease Patients NCT06120569 | Nora Hussein Kamal | N/A |
| Recruiting | Clinical Outcome of Vinpocetine in Diabetic Nephropathy NCT06441591 | Ain Shams University | Phase 2 / Phase 3 |
| Active Not Recruiting | Efficacy of Dapagliflozin in Early Diabetic Nephropathy in Type 1 Diabetes NCT06532682 | The First Affiliated Hospital with Nanjing Medical University | Phase 4 |
| Recruiting | Multimodal Magnetic Resonance Imaging in Evaluation of Diabetic Kidney Disease NCT06452862 | Shengjing Hospital | — |
| Recruiting | Prevalence and Management Practice of Diabetic Kidney Disease at BADAS Affiliated Healthcare Centres in Bangla NCT06422598 | Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders | — |
| Recruiting | Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes NCT05822609 | University of Washington | Phase 2 |
| Recruiting | Mechanism of SGLT2 Inhibition in the Kidney NCT06291155 | University of Michigan | Phase 4 |
| Unknown | Treatment of Patients With Diabetic Kidney Disease NCT06187493 | Assiut University | N/A |
| Recruiting | A Long-Term Follow-Up Study of Participants Exposed to REACT NCT05918523 | Prokidney | — |
| Enrolling By Invitation | Long-Term Follow-up Study of Participants Exposed to Renal Autologous Cell Therapy Frozen Product NCT06790498 | Prokidney | — |
| Not Yet Recruiting | Diagnostic Value of Serum Cathepsin S and Chromogranin A in DKD NCT06069076 | Assiut University | — |
| Unknown | The Influence of the Thickening of Bowman's Capsule on the Clinical Prognosis of Patients With Diabetic Kidney NCT06049550 | RenJi Hospital | — |
| Enrolling By Invitation | Plant-Focused Nutrition in Patients With Diabetes and Chronic Kidney Disease NCT05514184 | University of California, Irvine | N/A |
| Unknown | Efficacy and Safety of QiShen YiQi Dripping Pills in the Treatment of Diabetic Kidney Disease (Syndrome of Qi NCT06006689 | Tasly Pharmaceutical Group Co., Ltd | Phase 2 |
| Terminated | Feasibility of Aggressive Albuminuria Reduction in Biopsy-Proven Diabetic Nephropathy - a Pilot Study NCT05897372 | Iain Bressendorff | Phase 2 |
| Terminated | A Study of Participants With Chronic Kidney Disease Previously Treated With REACT NCT05694169 | Prokidney | Phase 1 |
| Completed | DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodyna NCT05727579 | Amsterdam UMC, location VUmc | Phase 4 |
| Active Not Recruiting | A Study to Evaluate the Efficacy and Safety of SC0062 in the Treatment of Chronic Kidney Disease NCT05687890 | Biocity Biopharmaceutics Co., Ltd. | Phase 2 |
| Completed | To Evaluate the Beneficial Effect of Probiotics on DKD Patients and the Role of Gut Microbiota Modulation NCT05674981 | GenMont Biotech Incorporation | N/A |
| Recruiting | NAD Augmentation in Diabetes Kidney Disease NCT05759468 | Brigham and Women's Hospital | Phase 2 |
| Unknown | Azilsartan in Patients With Diabetic Kidney Disease and Hypertension NCT05753696 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Completed | Efficacy and Safety of SPH3127 Tablets on Treating the Diabetic Kidney Disease NCT05593575 | Shanghai Pharmaceuticals Holding Co., Ltd | Phase 2 |
| Completed | Role of QRX-3 in Chronic Kidney Disease Patients in Outpatients Clinics NCT06948292 | Ebima Clifford Okundaye | Phase 2 |
| Completed | Biorepository of Biospecimen Samples in Matched Healthy Control Participants and Participants Diagnosed With D NCT05631119 | Sanguine Biosciences | — |
| Completed | Mesenchymal Stem Cell Therapy in Diabetic Kidney Disease-A Double-blind, Placebo-controlled, Randomized Clinic NCT07039318 | National Institute of Blood and Marrow Transplant (NIBMT), Pakistan | Phase 2 |
| Recruiting | Effects and Safety of Diabetic GUideline Algorithm Implementation Performed by Primary Care Physicians in the NCT05349955 | Shanghai Zhongshan Hospital | N/A |
| Completed | Phase 2 Study of INV-202 in Patients With Diabetic Kidney Disease NCT05514548 | Inversago Pharma Inc. | Phase 2 |
| Recruiting | Renal Mechanism of SGLT2 Inhibition NCT05507892 | University of Colorado, Denver | Phase 2 |
| Enrolling By Invitation | Renal Hemodynamics, Energetics and Insulin Resistance: A Follow-up Study NCT05530356 | University of Colorado, Denver | — |
| Unknown | Clinical Study on the Treatment of Diabetic Kidney Disease With Shenxiao Yuning Decoction With Syndrome of Qi NCT06176599 | Lin Liao | N/A |
| Recruiting | Multidimensional Accurate Diagnosis and Treatment Technology and Clinical Transformation of Type 2 Diabetes Ne NCT05888909 | Chinese PLA General Hospital | — |
| Recruiting | MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sen NCT05065372 | Kalie Tommerdahl | Phase 1 |
| Terminated | Targeting Leukotrienes in Kidney Disease NCT05362474 | University of Colorado, Denver | Phase 3 |
| Unknown | The Effects of Calcitriol on Biomarkers in Diabetic Kidney Disease Patients NCT05298163 | Indonesia University | N/A |
| Recruiting | Pathogenesis of Kidney Disease in Type 1 Diabetes: a Modern Kidney Biopsy Cohort (The PANDA Study) NCT05319990 | University of Colorado, Denver | — |
| Completed | Basal Plus GLP1-ra on Glycemic Variability in CKD NCT05218915 | Elaine Chow | Phase 4 |
| Not Yet Recruiting | Establishment and Clinical Validation of a New Technique for Early Diagnosis of Diabetic Nephropathy NCT04976426 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Unknown | To Improve the Ability of Early Screening and Diagnosis in Patients With Diabetic Nephropathy NCT05047471 | Yiming Mu | — |
| Active Not Recruiting | Prospective Decision Impact Trial of KidneyIntelX NCT04960514 | Renalytix AI, Inc. | — |
| Completed | Study of Roxadustat's Effect on Anemia in Patients With Diabetic Kidney Disease NCT07359027 | Second Xiangya Hospital of Central South University | Phase 4 |
| Active Not Recruiting | Prospective Decision Impact Clinical Utility Trial of KidneyIntelX NCT05198284 | Renalytix AI, Inc. | — |
| Recruiting | Decision Impact Trial of KidneyIntelX NCT04791358 | Renalytix AI, Inc. | — |
| Completed | An Observation Study to Evaluate the Renoprotective Effect of Fimasartan in Patients With DKD and Proteinuria NCT05086549 | Boryung Pharmaceutical Co., Ltd | — |
| Recruiting | Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study) NCT05008276 | Petter Bjornstad | — |
| Completed | SER150 vs Placebo in Diabetic Kidney Disease NCT04881123 | Serodus AS | Phase 2 / Phase 3 |
| Completed | Effects of Thai Dance Meditation Exercise on Renal and Cerebrovascular Function in Elderly With Diabetic Kidne NCT06578325 | Chulalongkorn University | N/A |
| Recruiting | Diabetic Nephropathy in People With Diabetes. Prevalence and Predictive Factors NCT04916132 | Herlev Hospital | — |
| Recruiting | Dosimetry of Tc-99m-Tilmanocept NCT05241522 | University of California, San Diego | Phase 1 |
| Terminated | Effect of Subcutaneous Semaglutide on Kidney Transplant Candidacy NCT04741074 | Geisinger Clinic | Phase 3 |
| Completed | Metabolism of Low Carbohydrate and Ketogenic Diet NCT05071287 | The University of Texas Health Science Center at San Antonio | N/A |
| Completed | Automatic Segmentation Ultrasound-based Radiomics Technology in Diabetic Kidney Disease NCT05025540 | Second Affiliated Hospital, School of Medicine, Zhejiang University | — |
| Withdrawn | A Trial to Learn More About How BAY2327949 Works and How Safe it is in Patients Whose Kidneys Are Damaged Due NCT04661917 | Bayer | Phase 2 |
| Unknown | Impact of Long-term Serum Magnesium and Potassium Levels Optimization and Multifactorial Adherence Interventio NCT04942119 | United Arab Emirates University | N/A |
| Active Not Recruiting | Atrasentan in Patients With Proteinuric Glomerular Diseases NCT04573920 | Novartis Pharmaceuticals | Phase 2 |
| Recruiting | Real World Evidence Clinical Utility Study of KidneyIntelX NCT04802395 | Renalytix AI, Inc. | — |
| Completed | Renal Oxygenation, Oxygen Consumption and Hemodynamic Kinetics in Type 2 DIabetes: an Ertugliflozin Study. NCT04027530 | Amsterdam UMC, location VUmc | Phase 4 |
| Completed | Renohemodynamic Effects of Combined empagliflOzin and LosARtan NCT04238702 | Amsterdam UMC, location VUmc | Phase 4 |
| Unknown | Kidney Fat in Type 2 Diabetes and the Effects of Ezetimibe NCT04589351 | Steno Diabetes Center Copenhagen | Phase 3 |
| Completed | Effects of Probiotics and Fibers on Albuminuria in Persons With Type 1 Diabetes NCT04635670 | Steno Diabetes Center Copenhagen | N/A |
| Unknown | Uric Acid Lowering Trial in Youth Onset T2D NCT03899883 | University of Colorado, Denver | Phase 2 |
| Completed | Control of Renal Oxygen Consumption, Mitochondrial Dysfunction, and Insulin Resistance NCT04074668 | University of Colorado, Denver | — |
| Completed | Role of Fexofenadine in Diabetic Kidney Disease NCT04224428 | Tanta University | Phase 3 |
| Active Not Recruiting | Pentoxifylline in Diabetic Kidney Disease NCT03625648 | VA Office of Research and Development | Phase 4 |
| Completed | A Phase 2b Diabetic Kidney Disease Study NCT04170543 | AstraZeneca | Phase 2 |
| Terminated | Patient-Derived Stem Cell Therapy for Diabetic Kidney Disease NCT03840343 | Mayo Clinic | Phase 1 |
| Unknown | Possible Ameliorating Effect of N- Acetylcysteine (NAC) on Type-II Diabetes Induced Nephropathy NCT04531163 | Al-Azhar University | Phase 2 / Phase 3 |
| Active Not Recruiting | MEtabolic and Renal Effects of AutoMAted Insulin Delivery Systems in Youth With Type 1 Diabetes Mellitus NCT03945747 | University of Colorado, Denver | — |
| Completed | Study to Evaluate the Efficacy and Safety of Selonsertib in Participants With Moderate to Advanced Diabetic Ki NCT04026165 | Gilead Sciences | Phase 2 |
| Completed | Evaluation of Coffee Therapy for Improvement of Renal Oxygenation NCT03878277 | University of Colorado, Denver | Phase 2 |
| Completed | Low Carbohydrate Diet in Diabetic Kidney Disease NCT04931030 | Universiti Teknologi Mara | N/A |
| Completed | Safety and Effectiveness of Propagermanium in Diabetic Kidney Disease Participants Receiving Irbesartan NCT03627715 | Dimerix Bioscience Pty Ltd | Phase 2 |
| Completed | Impact of Metabolic Surgery on Pancreatic, Renal and Cardiovascular Health in Youth With Type 2 Diabetes NCT03620773 | University of Colorado, Denver | Phase 1 / Phase 2 |
| Recruiting | Prognostic Imaging Biomarkers for Diabetic Kidney Disease NCT03716401 | University of Leeds | — |
| Unknown | The Association Between sUCR and the Survival in Patients With DKD NCT04612595 | Guangdong Provincial People's Hospital | — |
| Unknown | Efficacy, Safety and Response Predictors of Adjuvant Astragalus Therapy for Diabetic Kidney Disease NCT03535935 | The University of Hong Kong | Phase 2 / Phase 3 |
| Terminated | A Phase 3 Study of Bardoxolone Methyl in Patients With Diabetic Kidney Disease; AYAME Study NCT03550443 | Kyowa Kirin Co., Ltd. | Phase 3 |
| Completed | Phase 2 Study of TMX-049 in Subjects With Type 2 Diabetes and Albuminuria NCT03449199 | Teijin America, Inc. | Phase 2 |
| Completed | Determining Serum and Urinary Levels of miRNA 192 and miRNA 25 in Patients With and Without Type 2 Diabetes. NCT04176276 | University of Pisa | — |
| Terminated | Efficacy of a High-intensity Physical Activity Program on Renal Function in High Risk Patients With Type 2 Dia NCT03184662 | Poitiers University Hospital | N/A |
| Completed | A Double-blind Study to Investigate Efficacy, Safety and Tolerability of BAY1142524 in Patients With Type II D NCT03412006 | Bayer | Phase 2 |
| Completed | Effect of the Teleconsultation of Renal Nutrition on Renal Function and Glycemic Control in Patients With DKD NCT03344549 | Hospital Civil Juan I. Menchaca | N/A |
| Terminated | NEPHSTROM for Diabetic Kidney Disease NCT02585622 | Mario Negri Institute for Pharmacological Research | Phase 1 / Phase 2 |
| Recruiting | Correlation Study Between Clinical Phenotype and Pathology of Type 2 Diabetic Nephropathy NCT03865914 | Chinese PLA General Hospital | — |
| Completed | Efficacy and Safety of Jinshuibao Capsule on Diabetic Kidney Disease NCT03164785 | Second Xiangya Hospital of Central South University | Phase 2 / Phase 3 |
| Withdrawn | IvaBradinE to Treat MicroalbumiNuria in Patients With Type 2 Diabetes and Coronary Heart Disease NCT03105219 | Nanjing First Hospital, Nanjing Medical University | Phase 3 |
| Withdrawn | Empaglifozin in Early Diabetic Kidney Disease NCT03173963 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Phase 3 |
| Completed | EMPRA (EMPagliflozin and RAs in Kidney Disease) NCT03078101 | Medical University of Vienna | Phase 2 |
| Completed | Effect of Urinary Alkalinization on Urine Uric Acid Precipitation and Crystallization in Adults With Type 1 Di NCT02502071 | University of Colorado, Denver | Phase 4 |
| Unknown | The Multi-Center Clinical Study of Tang Shen Prescription on Type 2 Diabetic Kidney Disease in Early Stage NCT03009864 | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | EARLY_Phase 1 |
| Unknown | Clinical Trial of HuangKui Capsule to Treat Diabetic Kidney Disease NCT03016832 | Jiangsu Famous Medical Technology Co., Ltd. | EARLY_Phase 1 |
| Completed | Non Diabetic Causes of Chronic Kidney Disease in Type 2 Diabetic Patients NCT05021705 | Assiut University | — |
| Completed | Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and the Clinical Diagnosis of Diab NCT02545049 | Bayer | Phase 3 |
| Completed | Study to Evaluate the Pharmacokinetics of Selonsertib in Participants With Normal and Impaired Hepatic Functio NCT02509624 | Gilead Sciences | Phase 1 |
| Completed | Antiproteinuric Effects of Liraglutide Treatment NCT02545738 | Steno Diabetes Center Copenhagen | Phase 4 |
| Completed | Integrated Population Program for Diabetic Kidney Disease NCT02418091 | Duke University | N/A |
| Completed | Association of BsmI Polymorphisms in Vitamin D Receptor Gene With Diabetic Kidney Disease NCT03621384 | Indonesia University | — |
| Unknown | Mechanisms of Diabetic Nephropathy in Ecuador NCT02237352 | Universidad Estatal de Milagro | — |
| Completed | Effect of LIXIsenatide on the Renal System NCT02276196 | Amsterdam UMC, location VUmc | Phase 4 |
| Terminated | Pyridorin in Diabetic Nephropathy NCT02156843 | NephroGenex, Inc. | Phase 3 |
| Completed | Using a Diabetic Kidney Disease (DKD) Registry to Treat to Multiple Targets (TMT) NCT02176278 | Asia Diabetes Foundation | N/A |
| Completed | Efficacy, Safety, and Tolerability of Selonsertib (GS-4997) in Participants With Diabetic Kidney Disease NCT02177786 | Gilead Sciences | Phase 2 |
| Completed | Simultaneous Risk Factor Control Using Telehealth to slOw Progression of Diabetic Kidney Disease (STOP-DKD) NCT01829256 | Duke University | N/A |
| Withdrawn | Prevention of Microvascular Complications in Overweight Diabetics With Surgery or Best Medicine NCT02011178 | Karolinska Institutet | N/A |
| Completed | Impact of Multidisciplinary Self-care Management of Diabetic Nephropathy on Quality of Life, Self-care Behavio NCT01967901 | University of Applied Sciences of Western Switzerland | N/A |
| Active Not Recruiting | The Hong Kong Diabetes Biobank NCT05282680 | Chinese University of Hong Kong | — |
| Completed | The Phase I Clinical Study to Evaluate the Pharmacokinetics of Dw1029M in Healthy Male Volunteer NCT02004327 | Dong Wha Pharmaceutical Co. Ltd. | Phase 1 |
| Suspended | Mechanisms of Diabetic Kidney Disease in American Indians NCT01878045 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |
| Completed | The Effect of Glucagon-like-peptide 1 (GLP-1) Receptor Agonism on Diabetic Kidney Disease NCT01847313 | Karl Neff | Phase 3 |
| Terminated | Study to Evaluate the Effects of BMS-813160 on Protein Loss in the Urine of Subjects With Type 2 Diabetes and NCT01752985 | Bristol-Myers Squibb | Phase 2 |
| Completed | A Study to Test Safety and Efficacy of Baricitinib in Participants With Diabetic Kidney Disease NCT01683409 | Eli Lilly and Company | Phase 2 |
| Completed | Very Low Calorie Diet for Diabetic Kidney Disease NCT01671969 | Indiana University | N/A |
| Completed | Personalized Diabetic Kidney Disease Risk Info to Initiate and Maintain Health Behavior Changes NCT01377688 | Duke University | — |
| Completed | Impact of Vitamin D on Diabetic Kidney Disease in African Americans NCT01214356 | Medical University of South Carolina | N/A |
| Terminated | A Study in Participants With Diabetic Kidney Disease NCT01113801 | Eli Lilly and Company | Phase 2 |
| Terminated | Study of FibroGen (FG)-3019 in Subjects With Type 2 Diabetes Mellitus and Kidney Disease on ACEi and/or ARB Th NCT00913393 | Kyntra Bio | Phase 2 |
| Terminated | Rhubarb and Angiotensin Converting Enzyme Inhibitor NCT00672451 | Wake Forest University | Phase 2 |
| Completed | Randomized Controlled Trial of Vitamin D3 in Diabetic Kidney Disease NCT00552409 | University of Washington | Phase 2 / Phase 3 |
| Completed | High Dose Ace Inhibitor Therapy Versus Combination of ACE and ARB Therapy NCT00212901 | Ottawa Hospital Research Institute | N/A |
| Recruiting | Family Investigation of Nephropathy and Diabetes (F.I.N.D.) NCT00342927 | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | — |