Clinical Trials Directory

Trials / Terminated

TerminatedNCT01113801

A Study in Participants With Diabetic Kidney Disease

A Randomized, Double-Masked, Placebo-Controlled, Multicenter, Phase 2 Study to Evaluate the Safety and Renal Efficacy of LY2382770 in Patients With Diabetic Kidney Disease Due to Type 1 or Type 2 Diabetes

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
417 (actual)
Sponsor
Eli Lilly and Company · Industry
Sex
All
Age
25 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine if LY2382770 is safe and effective at protecting kidney function in participants with kidney disease due to diabetes.

Detailed description

The primary objective is to determine if LY2382770, administered monthly for 1 year, is more effective than placebo at slowing the progression of diabetic kidney disease in participants treated with an angiotensin-converting enzyme inhibitor (ACEi) or an angiotensin II receptor blocker (ARB).

Conditions

Interventions

TypeNameDescription
DRUGLY2382770Subcutaneous injection given monthly for 12 months
DRUGPlaceboSubcutaneous injection given monthly for 12 months

Timeline

Start date
2010-07-01
Primary completion
2014-05-01
Completion
2014-07-01
First posted
2010-04-30
Last updated
2019-09-17
Results posted
2017-12-13

Locations

78 sites across 7 countries: United States, Australia, Czechia, France, Hungary, Israel, Puerto Rico

Source: ClinicalTrials.gov record NCT01113801. Inclusion in this directory is not an endorsement.