| Not Yet Recruiting | Task-Shifting for Youth Suicide Prevention NCT07383831 | Boston College | N/A |
| Not Yet Recruiting | The Oh Happy Day Class - Digital Connections (OHDC-DC): A Pilot Study NCT06206226 | University of Wisconsin, Madison | N/A |
| Not Yet Recruiting | Mindfulness Engaged Neurostimulation for Depression (MEND II) NCT07512284 | University of California, San Diego | Phase 2 |
| Not Yet Recruiting | Activating Social Resources in Psychotherapy-Seeking Individuals: Effectiveness and Timing of a Social Support NCT07471529 | University of Zurich | N/A |
| Not Yet Recruiting | Examining the Health Effects of NPOWER365 Among Black Same Gender Loving Men NCT06315218 | Rutgers, The State University of New Jersey | N/A |
| Not Yet Recruiting | Efficacy of Digital Problem Solving Application in Reduction of Anxiety, Depression and Substance Use Disorder NCT06346431 | 7 Generation Games | EARLY_Phase 1 |
| Recruiting | VR-PMR for Post-Burn Symptoms NCT07317271 | Johns Hopkins University | N/A |
| Not Yet Recruiting | MindfulCityU-- A Mindfulness Mobile Application for Promoting University Students' Mental Health NCT07392632 | City University of Hong Kong | N/A |
| Not Yet Recruiting | Evaluation of MBCT Implemented in Vietnamese Buddhist Pagoda NCT06598579 | Vanderbilt University | N/A |
| Not Yet Recruiting | Strength and Pain-Coping Through Resilience and Knowledge NCT07228520 | Johns Hopkins University | N/A |
| Not Yet Recruiting | Objective Vascular Biomarkers as Triage for Depression in Chronic Atrophic Gastritis NCT07319338 | China Academy of Chinese Medical Sciences | — |
| Recruiting | IMB-Based Sleep Hygiene Education for Menopausal Women: Effects on Sleep Quality and Depression NCT07299903 | Ankara Yildirim Beyazıt University | N/A |
| Recruiting | BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Urinary Incontinence in Postpa NCT07413692 | BTL Industries Ltd. | N/A |
| Recruiting | BTL-699-2 and HPM-6000UF Devices for the Improvement of Depressive Symptoms and Sexual Function Among Perimeno NCT07413705 | BTL Industries Ltd. | N/A |
| Not Yet Recruiting | A Study on the Effectiveness of Comprehensive Intervention Based on Specialized Physical Education Courses in NCT07237698 | Xiaoyan Wu | N/A |
| Enrolling By Invitation | Cannabis, Neuroinflammation, and Suicidal Ideation: A Supplemental Brain Imaging Study NCT07222306 | Wayne State University | — |
| Recruiting | Lifestyle Interventions to Prevent Cognitive Deficits in Subjects With Depressive Symptoms: From Mechanisms to NCT07009223 | IRCCS Centro San Giovanni di Dio Fatebenefratelli | N/A |
| Completed | Comparing the Effectiveness of Reappraisal Strategies in Adult Participants NCT07008209 | Ibn Haldun University | N/A |
| Recruiting | Psychological Well-Being, Depression, and Health-Related Quality of Life in Adults With Type 2 Diabetes: A Cro NCT07241325 | National Taiwan University Hospital | — |
| Recruiting | Assessment of Daily Stressors in Children With Depressive Symptoms for the Development of a Gamified Emotion R NCT07159347 | Ludwig-Maximilians - University of Munich | — |
| Recruiting | A Remotely Delivered Tai Chi/Qigong Intervention for Older People Living With HIV NCT06586619 | Florida International University | N/A |
| Enrolling By Invitation | Occupational Therapy for Mental Health and Engagement in Neurorehabilitation NCT07375485 | Colorado State University | N/A |
| Recruiting | Our Voices Matter: Intervention for Depression in Youth NCT07216326 | Ann & Robert H Lurie Children's Hospital of Chicago | N/A |
| Not Yet Recruiting | Collaborative Redesign of Implementation Strategies for the Brief Intervention for School Clinicians NCT06968949 | University of Washington | N/A |
| Not Yet Recruiting | Project ICOPE Brazil: Assessment of Intrinsic Capacity in Brazilian Older Adults NCT06968702 | University of Sao Paulo | — |
| Recruiting | Video-feedback Intervention to Promote Racial-Ethnic Socialization Competency (VIP-RACE) NCT07055906 | Penn State University | N/A |
| Not Yet Recruiting | Between the Belly and the Brain: Distorted Gut-brain Crosstalk in Early-life Adversity NCT06922773 | Universitair Ziekenhuis Brussel | — |
| Recruiting | Project COPE-Spain (Coping Options for Parent Empowerment) NCT07006220 | Universidad Nacional de Educación a Distancia | N/A |
| Recruiting | Benefits of Outdoor Walks in Reducing Depressive Symptoms NCT06989801 | University of Washington | N/A |
| Not Yet Recruiting | 10-year Follow-up After Aortic Valve Replacement Surgery NCT06255691 | Oslo University Hospital | — |
| Recruiting | Culturally Adapted i-CBT for Farsi/Dari Speaking Migrants NCT06828276 | Karolinska Institutet | N/A |
| Recruiting | Improving Mood for Adolescents Through Teaming With End-Users in Routine Care (The iMATTER Project) NCT07020572 | Children's Hospital of Philadelphia | N/A |
| Completed | Flywheel Resistance Training and Traditional Resistance Training in Older Women With Sedentary Behaviors NCT06758206 | Federal University of Vicosa | N/A |
| Active Not Recruiting | The Mindfulness-Based Psycho-Educational Program Focused on Emotion Regulation Strategies NCT06926049 | Gazi University | N/A |
| Not Yet Recruiting | Web-app Based Lifestyle Physical Activity Promotion Program (WPAPP) for Middle Aged Latinas NCT06768801 | University of Texas at Austin | N/A |
| Recruiting | Music Therapy's Impact on University Students' Social and Mental Health NCT07024979 | The University of Hong Kong | N/A |
| Recruiting | Augmentation of EMDR With tDCS in the Treatment of Fibromyalgia NCT04084795 | Parc de Salut Mar | N/A |
| Recruiting | Strengthening Health and Insight in New Educators NCT06745934 | University of Alabama, Tuscaloosa | N/A |
| Recruiting | Michigan Men's Diabetes Project III(MenDIII): Mind and Motion NCT06574035 | University of Michigan | N/A |
| Recruiting | rTMS for Military TBI-related Depression NCT05426967 | Henry M. Jackson Foundation for the Advancement of Military Medicine | N/A |
| Recruiting | Telephone-coached "Graphic Narrative" Bibliotherapy for Dementia Caregivers NCT06413849 | The Hong Kong Polytechnic University | N/A |
| Recruiting | Depressive Symptoms After Cardiac Surgery NCT06706323 | Roland von Känel | — |
| Active Not Recruiting | The Purpose of the Study is to Investigate if a Smartphone App Combined With Internet Based Cognitive Behaviou NCT06907134 | Linkoeping University | N/A |
| Recruiting | Improving Sleep to Prevent Depression & Anxiety in Adolescents at High Risk NCT06358495 | University of Calgary | N/A |
| Recruiting | IMPACT (IMproving Proactive Approaches for Cancer Survivors' Mental Health Treatment) NCT06582784 | Medical University of South Carolina | N/A |
| Recruiting | Effectiveness of a Guided Mobile App Intervention for Depression and Anxiety in University Students (PROMES-U NCT06078007 | University of the Balearic Islands | N/A |
| Completed | College Student Stress: Transitions Over Time NCT06583096 | University of Michigan | N/A |
| Active Not Recruiting | Effectiveness of a Mobile Application in Improving Employees' Social Well-being. NCT06495801 | University of Eastern Finland | N/A |
| Recruiting | Natural History of Depression, Bipolar Disorder and Suicide Risk NCT06462196 | National Institute of Mental Health (NIMH) | — |
| Enrolling By Invitation | Cluster RCT of Cognitive Behavioral Therapy to Support Caregivers of Older Adults in Hong Kong NCT06473012 | The University of Hong Kong | N/A |
| Not Yet Recruiting | e-Intervention Enhancing Mental Health in Adolescents NCT06556576 | Fundació Sant Joan de Déu | N/A |
| Not Yet Recruiting | Mind Nutrition Study. Effectiveness of Improving Nutrition on Depressive Symptoms and Work Ability NCT06448117 | Satakunta University of Applied Sciences | N/A |
| Recruiting | Non-pharmacological Care for Depression in Cancer Patients Using VR and TMS NCT06589544 | University Hospital of Ferrara | N/A |
| Recruiting | Low Voltage Electrical Stimulation for Depression in Parkinson's Patients NCT06467695 | University of South Alabama | N/A |
| Recruiting | Social Worker-led Mindfulness-based Intervention for Older People NCT06528132 | The University of Hong Kong | N/A |
| Completed | Evaluation of Teen Connection Project for Trans and Gender Minority Youth NCT06587139 | University of Michigan | N/A |
| Completed | The Effect of Auricular Press Needle on Visual Analogue Scale (VAS) and Short Form (SF-12) Scores in Chronic P NCT06401031 | Indonesia University | N/A |
| Completed | Group CA-CBT Intervention to Reduce Psychological Distress of Earthquake Survivors NCT06189937 | Koç University | N/A |
| Recruiting | Behavioral Activation for the Prevention and Treatment of Depression in Older Adults in a Municipal Context NCT06415838 | Sormland County Council, Sweden | N/A |
| Recruiting | Building Resilience for Surgical Recovery NCT06174701 | The University of Texas Health Science Center, Houston | N/A |
| Not Yet Recruiting | The MIND-GUT Digital Pilot Intervention Study NCT06374407 | University of Skövde | N/A |
| Not Yet Recruiting | Intervention for Emotions in Caregivers of Dementia NCT06359704 | The University of Hong Kong | N/A |
| Enrolling By Invitation | Efficacy of a Mobile Phone App for Depression and Anxiety in College Students NCT06628830 | University of Chile | N/A |
| Enrolling By Invitation | Syrenity App for Depression NCT06408025 | Indiana University | N/A |
| Not Yet Recruiting | A Single-case Design to Investigate a Compensatory Brain Game Supporting Goal Management Training Intervention NCT06352346 | ProPersona | N/A |
| Recruiting | A New Clinical Model for the Engagement of Latinx Youth With Suicidal Behavior NCT06882798 | Bradley Hospital | N/A |
| Completed | Self-Compassion to Enhance the Well-Being of Caregivers of Children With Physical Disabilities NCT06271824 | University of North Carolina, Chapel Hill | N/A |
| Recruiting | Expressive Writing on Minority Stressors Among Sexual Minority Veterans NCT05897021 | VA Office of Research and Development | N/A |
| Completed | An Evaluation of the Effect of Vitamin D Supplementation on Depressive Symptoms Among Chinese Early Adolescent NCT06247930 | Anhui Medical University | N/A |
| Active Not Recruiting | Treatment for Migraine and Mood NCT05576467 | Amanda Shallcross | N/A |
| Active Not Recruiting | ICBT for Anxiety and Depressive Symptoms in Brazilian Young Adults NCT06633679 | Linkoeping University | N/A |
| Completed | High- vs Low-Frequency Exercise for Depression in Adolescents NCT06677723 | Je Bouge Pour Mon Moral | N/A |
| Completed | Effect of Lavender Aromatherapy on Preoperative Anxiety, Stress, and Depression in Orthopedic Surgery Patients NCT07513831 | Al-Zaytoonah University of Jordan | N/A |
| Completed | The Feasibility of Cognitive Process Therapy in Earthquake-affected Population With Mental Health Problems in NCT06136481 | Koç University | N/A |
| Unknown | Metacognitive Training-Silver BeWell in Older Adults NCT06312241 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Recruiting | Cancer Pain Management Using a Web-based Intervention NCT06085313 | University of Texas at Austin | N/A |
| Completed | Does a Novel Intervention Targeting Derailment Decrease Depressive Symptoms? NCT06265701 | Cornell University | N/A |
| Active Not Recruiting | Evaluating a Virtual Mentoring Program Plus Mental Health Videos for Teens NCT06138730 | Appa Health | N/A |
| Completed | Rare Group Problem Management Plus NCT06548022 | Children's National Research Institute | N/A |
| Completed | Evaluation of a Transdiagnostic Mobile App Intervention Among University Students NCT06224647 | Erasmus University Rotterdam | N/A |
| Unknown | "Youth Aware of Mental Health" in Galicia NCT06251037 | Fundacin Biomedica Galicia Sur | N/A |
| Recruiting | Cognitive Control Mechanisms in Older Adults NCT06631781 | Hebrew University of Jerusalem | N/A |
| Completed | Supporting Methods in Cardiovascular Diseases Rehabilitation NCT06241534 | Wroclaw University of Health and Sport Sciences | N/A |
| Recruiting | Pilot Study of a Multidisciplinary Intervention in ICU Survivors At Risk for Psychological or Physical Morbidi NCT06118606 | Region Stockholm | N/A |
| Recruiting | Online or In-person Interventions on Anxiety and Depression Symptoms in Caregivers of Patients with Cancer NCT06592573 | Fondazione ANT Italia ONLUS | N/A |
| Completed | ACT-group for Stroke Survivors (Pilot Study) NCT06282029 | Bielefeld University | N/A |
| Recruiting | Dog Presence and Oxytocin on Trust Towards Therapists NCT06248710 | Dr. Karin Hediger | Phase 2 / Phase 3 |
| Completed | Psychological Health and Adverse Childhood Experiences in Myasthenia Gravis: Online Mental Health BMI Learning NCT07291713 | Jiann-Horng Yeh | N/A |
| Active Not Recruiting | Effectiveness of the Universal Prevention Program Super Skills for Life in Schools NCT06444581 | Universidad Miguel Hernandez de Elche | N/A |
| Completed | Smart Phone Delivered Cognitive Behavioral Therapy for Adults With Psoriasis and Co-Morbid Depression Symptoms NCT06216691 | Brigham and Women's Hospital | N/A |
| Completed | Cultural Arts Programme for Older Chinese NCT06527625 | The Hong Kong Polytechnic University | N/A |
| Unknown | Effect of Esketamine on Depressive Symptoms of Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy NCT06199011 | The Second Hospital of Anhui Medical University | N/A |
| Recruiting | Music Program for Hong Kong Adolescents: Improving Emotion Regulation and Reducing Depression, Anxiety, and Lo NCT06147297 | The University of Hong Kong | N/A |
| Recruiting | Depression and Suicide Prevention in Adolescents Attending Special Schools NCT06203899 | Ggz Oost Brabant | N/A |
| Unknown | Instant Message-delivered Cognitive Behavioural Therapy for Insomnia (CBT-I)Stroke Caregivers NCT05952245 | The University of Hong Kong | N/A |
| Completed | Culturally Adapted iCBT for Arabic-speaking Refugee and Migrant Youth With Common Mental Health Problems NCT06102096 | Karolinska Institutet | N/A |
| Unknown | Study of Positive Psychology and Effects on Well-being of Anaesthesiologists in Hong Kong NCT06148454 | Hong Kong College of Anaesthesiologists | N/A |
| Completed | A Scalable Psychological Intervention for Earthquake Survivors in Türkiye NCT06026306 | Koç University | N/A |
| Completed | Mindfulness-based Zentangle for Parents NCT06094803 | Hong Kong Metropolitan University | N/A |
| Withdrawn | Ketamine-Assisted PsychoTherapy ViAbility in Treating Cancer-related Emotional Distress NCT05344625 | Northwell Health | EARLY_Phase 1 |
| Completed | ABSORB (Amount of Blueberries So Older Adults Reap Benefits) NCT05937165 | Hebrew SeniorLife | N/A |
| Recruiting | Implementation of Bright Light Therapy ID NCT06215235 | Erasmus Medical Center | — |
| Completed | Therapeutic Exercise on the Psychological Well-being of Women Victims of Gender Violence. NCT05981417 | University of Vigo | N/A |
| Completed | Effects of High Ventilation Breathwork With Retention (HVBR) on Health NCT06064474 | University of Sussex | N/A |
| Completed | Virtual Reality (VR) for Stress Management NCT06970652 | City University of New York, School of Public Health | N/A |
| Recruiting | Survivorship Care for Women Living With Ovarian Cancer: (POSTCARE-O) NCT05752448 | Baylor College of Medicine | N/A |
| Active Not Recruiting | Module-Based Psychological (MBP) for Community Youths NCT06005961 | The University of Hong Kong | N/A |
| Active Not Recruiting | Non-Invasive Brain Stimulation and Cognitive Training for Depressive Symptomatology Related to Breast Cancer ( NCT06053775 | University of Santiago de Compostela | N/A |
| Completed | Effects of Integrated Exercise on Sarcopenia, Depression Symptoms, and Quality of Life NCT06637228 | Chang Gung University of Science and Technology | N/A |
| Completed | Digital Gaming Intervention for Older People in Long-term Care NCT06018974 | University of Oulu | N/A |
| Completed | Effectiveness of Fortification With Folic Acid and Vitamin B12 Among Teenage Girls NCT06100146 | University Ghent | N/A |
| Recruiting | The Supplementation Therapy in Autism and Response to Treatment Study NCT06187090 | University of Udine | N/A |
| Unknown | Breakthrough Anxiety and Sleep Evaluation Using Linked Devices and Smartphone Application Onar (BASEL) NCT06027047 | Raivotech | — |
| Unknown | Sharing HaRT in New Expanses NCT06237439 | University of Alabama, Tuscaloosa | N/A |
| Completed | Can Rumination-Focused Cognitive Behavioral Therapy Reduce the Risk of Cardio-vascular Disease? NCT05980130 | University of Louisville | N/A |
| Completed | Mental Health Mobile Apps for Adults NCT06099301 | Hong Kong Metropolitan University | N/A |
| Unknown | A Music-Based Mobile App for People Living With Alzheimer's Disease and Related Dementias (ADRD) NCT06140342 | Autotune Me LLC | — |
| Completed | SFGT for Persistent Anxiety and Depression NCT05942495 | GGZ Noord-Holland-Noord | N/A |
| Completed | Oxford Social Movement Activation Study NCT05963581 | University of Oxford | N/A |
| Recruiting | Profiling the Dynamic of Binge Eating Disorder (PRODY-BED) NCT05726721 | Aarhus University Hospital | — |
| Completed | School-based Group Acceptance and Commitment Therapy for Adolescents NCT06039228 | Chinese University of Hong Kong | N/A |
| Completed | PLANTS Pilot Trial NCT05897827 | University of Pittsburgh | N/A |
| Active Not Recruiting | Virtual Reality in Hemodialysis to Improve Psychological Well-being NCT05642364 | University of Illinois at Urbana-Champaign | N/A |
| Recruiting | Mobile CBT for Middle Aged and Older Adults NCT05754151 | Weill Medical College of Cornell University | N/A |
| Completed | Online Cognitive Behavioral Groupherapy for Mothers of Babies With Congenital Heart Disease NCT05956249 | Instituto de Cardiologia do Rio Grande do Sul | N/A |
| Completed | Feasibility and Acceptability of a Single Session of Imagery Rescripting in a Community Sample of Adults NCT06610318 | University of Oregon | EARLY_Phase 1 |
| Completed | Evaluation of a Proactive Identification and Digital Mental Health Intervention Approach to Address Unmet Psyc NCT05932810 | Medical University of South Carolina | N/A |
| Completed | Precision Mental Health in Diabetes - Subtypes of Mental Health, Trajectories, and Patterns With Glycaemic Con NCT05548699 | Forschungsinstitut der Diabetes Akademie Mergentheim | — |
| Recruiting | Instant Message-delivered Brief Internet-based Cognitive Behavioural Therapy (iCBT) for Post-stroke Depression NCT05892965 | The University of Hong Kong | N/A |
| Completed | A Single-Session Intervention for Adolescents and Young Adults With Internalizing Problems NCT05826392 | Baylor College of Medicine | N/A |
| Recruiting | Family Spirit Strengths NCT05836090 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Recruiting | Stepping Together for Children After Trauma, Norway NCT05734547 | Norwegian Center for Violence and Traumatic Stress Studies | N/A |
| Recruiting | Trauma-Focused Cognitive Behavioral Therapy in Unaccompanied Refugee Minors With PTSD in Greece: An RCT NCT06975280 | Theodora Anastasiou | N/A |
| Unknown | Using Machine Learning to Optimize User Engagement and Clinical Response to Digital Mental Health Intervention NCT05567640 | Boston University Charles River Campus | N/A |
| Recruiting | Mood and Thought Process Study NCT05585775 | Butler Hospital | N/A |
| Completed | Blueberries, Inflammation, Motivation, and Physical Activity NCT05735587 | Hebrew SeniorLife | N/A |
| Completed | Berries, Bugs, and the Blues NCT05817383 | Hebrew SeniorLife | N/A |
| Recruiting | Mind-Body Skills Group for Graduate Students NCT05447689 | Weill Medical College of Cornell University | N/A |
| Unknown | Effects of a Blended Indoor and Outdoor Physical Exercise Program on Depressive Symptoms in Hong Kong Older Ad NCT06190327 | Hong Kong Baptist University | N/A |
| Active Not Recruiting | Pain Reduction Through Empowered Recovery (PRIME) Study NCT05619510 | Johns Hopkins University | N/A |
| Active Not Recruiting | Glutamatergic Modulation as a Treatment for Depressive Symptoms Among Patients With Post-acute Sequelae of COV NCT05690503 | New York State Psychiatric Institute | Phase 2 |
| Recruiting | Transdiagnostic, Indicated Preventive Intervention for Adolescents At High Risk of Emotional Problems W/Add-On NCT06350760 | University of Jaén | N/A |
| Completed | Study to Evaluate TNX-601 ER Monotherapy Versus Placebo in Patients With Major Depressive Disorder (MDD) NCT05686408 | Tonix Pharmaceuticals, Inc. | Phase 2 |
| Recruiting | Efficacy and Safety of Auricular Acupuncture in Depression During the Covid 19 Pandemic NCT05855421 | Universidade do Sul de Santa Catarina | N/A |
| Unknown | Effects of High-Intensity Interval Training on Depressive Symptoms in Hong Kong Older Adults NCT06014294 | Hong Kong Baptist University | N/A |
| Active Not Recruiting | A Trial of a Positive Psychology Intervention for Older Adults (RESET) NCT05451589 | University of Michigan | N/A |
| Completed | Effects of Coherent Breathing Breathwork on Health NCT05676658 | University of Sussex | N/A |
| Completed | The Effects of Probiotic Supplementation on State and Trait Stress, Anxiety, and Depression Symptoms in Stress NCT07216729 | University of Colorado, Boulder | N/A |
| Completed | Acceptance Commitment Therapy for Caregivers of People with Memory Loss NCT05749939 | Utah State University | Phase 3 |
| Completed | Audio-based Mental Health Intervention Study NCT05555745 | Penn State University | N/A |
| Recruiting | Testing the Effectiveness of Supportive Parents - Coping Kids NCT05800522 | Norwegian Center for Child Behavioral Development | N/A |
| Completed | Optimization of a Mobile Transdiagnostic Emotion Regulation Intervention for University Students NCT05576883 | Erasmus University Rotterdam | N/A |
| Unknown | Effectiveness of Traditional and Computerized Versions of Super Skills for Life in Children NCT05574491 | Universidad Miguel Hernandez de Elche | N/A |
| Completed | Prevention of Long Covid Syndrome NCT05793736 | University of Cagliari | N/A |
| Unknown | Effects of Inserting Exercises During Physical Education Classes on Anxiety and Depression Symptoms in Adolesc NCT05561192 | Federal University of Pelotas | N/A |
| Recruiting | RXWell to Decrease Post-Operative Opioid Use in Total Knee or Hip Arthroplasty NCT05658796 | University of Pittsburgh | N/A |
| Terminated | Digital Therapeutic for Adolescent Depressive Symptoms in Hematology, Oncology, and Weight Management NCT05351866 | Limbix Health, Inc. | N/A |
| Unknown | CrisisCope: ICBT for Psychological Symptoms Related to Life Crises. NCT05673382 | Linkoeping University | N/A |
| Unknown | Metacognitive Training in the Older Adults With Depressive Symptoms (MCT-Silver) NCT05640492 | University of Évora | N/A |
| Unknown | Investigating the Effect of a Smartphone-based Serious Game on Depressive Symptoms. NCT04988529 | Universitat Jaume I | N/A |
| Completed | Bibliotherapy-based Psychoeducation Program the Effect of Elderly Individuals on Depression and Hopelessness L NCT05652803 | Istanbul Medeniyet University | N/A |
| Unknown | Self-administered Acupressure for Depression NCT05631184 | The Hong Kong Polytechnic University | N/A |
| Completed | Clinical Investigation of Wysa NCT05533190 | University of Plymouth | N/A |
| Completed | Online Cognitive Behavioral Therapy for Depressive Symptoms in Parkinson's Disease NCT05585827 | Helse Stavanger HF | N/A |
| Completed | Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression NCT05615948 | Maimonides Medical Center | Phase 4 |
| Recruiting | My Wellbeing Guide: a Novel Tool for Managing Stress and Improving Quality of Life NCT05369429 | Northwestern University | N/A |
| Completed | The Role of Music Therapy in Improving College Students' Mental Health and Self-efficacy NCT06917170 | Hubei University of Science and Technology | N/A |
| Completed | The Impact of PM+For Moms Intervention on Improving Mother's Mental Health in Zambia (PM+FM) NCT05627206 | Swiss Tropical & Public Health Institute | N/A |
| Unknown | The Effects of Walking in Nature (vs. an Urban Setting) on the Wellbeing of Postsecondary Students. NCT05889078 | McGill University | N/A |
| Completed | Efficacy Testing of a Culturally Relevant Stigma Intervention With WLWH in Tanzania NCT05033002 | Duke University | N/A |
| Not Yet Recruiting | Prediction and Validation of Unipolar Depression With Psychosocial-somatic Markers in a Naturalistic Cohort Re NCT05547711 | Julia Eder | N/A |
| Completed | Intervention Effect of Emotional Working Memory Training on University Students With Depressive Symptom NCT05861414 | Yu-hua Weng | N/A |
| Completed | Feasibility & Acceptability of a Virtual Sister Circle Intervention for Black Women With Depressive Symptoms NCT04837573 | Kia Skrine Jeffers, PhD, RN, PHN | N/A |
| Unknown | Physical Activity in the Format of Self-defence Training for Depressive Symptoms NCT05313542 | Chinese University of Hong Kong | N/A |
| Completed | Strategies for Coping With Negative Thoughts NCT05566691 | Ohio State University | N/A |
| Terminated | Digital Therapeutic for Adolescent Depressive Symptoms in Cardiology and Gastroenterology NCT05461599 | Limbix Health, Inc. | N/A |
| Completed | Piloting +Connection is Medicine / The Healing Spirits Program NCT05424679 | Johns Hopkins Bloomberg School of Public Health | N/A |
| Unknown | One Talk at a Time: A Racial-ethnic Socialization Intervention for Diverse Families NCT05454293 | University of North Carolina, Greensboro | N/A |
| Completed | Tai Chi Versus Conventional Exercise to Alleviate Depression in Insomniacs NCT05482646 | The University of Hong Kong | N/A |
| Active Not Recruiting | Disentangling Pharmacological and Expectation Effects in Antidepressant Discontinuation NCT05191277 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Unknown | The Efficacy of Acupressure Therapy on Patient With Depression NCT05423405 | University Psychiatric Clinics Basel | N/A |
| Completed | Self-guided Treatment for Adolescents Navigating Depression NCT05462652 | Limbix Health, Inc. | N/A |
| Recruiting | Caregiver Stress and Sleep Study NCT05219955 | University of Pittsburgh | N/A |
| Unknown | Emoji-based Attention Bias Modification Training for Depressive Young Adults NCT05415306 | Universiti Tunku Abdul Rahman | N/A |
| Active Not Recruiting | Digital Therapeutic for Depression After Head Injury in Current and Former US Military Personnel NCT05147506 | Henry M. Jackson Foundation for the Advancement of Military Medicine | N/A |
| Completed | Examining the Effectiveness of a Tablet Video Game on Mood and Cognition NCT05447091 | Hebrew University of Jerusalem | N/A |
| Completed | Examine the Effects of Mindfulness in Woman With a History of Child Adversity NCT05255380 | University of California, San Francisco | N/A |
| Completed | Mindfulness-Based Cognitive Therapy in Older People NCT05995587 | The University of Hong Kong | N/A |
| Unknown | Efficacy of an Online Self-help Program for Negative Affect and Depression NCT05293691 | University of Witten/Herdecke | N/A |
| Unknown | Studying the Effectiveness and Implementation of Sudarshan Kriya Yoga for Canadian Veterans With PTSD NCT05235828 | Mount Sinai Hospital, Canada | N/A |
| Completed | Comparing the Effects of Mindfulness-Based and Cognitive Behavioral-Based Stress Reduction in Medical Students NCT06156852 | Gazi University | N/A |
| Unknown | Effectiveness of AMICOPE Intervention to Maintain Self-Perceived Health and Intrinsic Capacity in Older People NCT05249504 | Fundacio Salut i Envelliment UAB | N/A |
| Completed | COVID-19 Research: COPE Trial in Health Care Workers NCT05271006 | University of British Columbia | N/A |
| Unknown | Implementation of a Psychological Online Intervention for Low to Moderate Depression in Primary Health Care NCT05294614 | Universitat Jaume I | N/A |
| Completed | A Ten-Week Online Acceptance and Commitment Therapy Intervention for Family Caregivers of People With Dementia NCT05043441 | University of Alabama at Birmingham | N/A |
| Completed | Virtual Therapeutic Garden for Depressive Symptoms NCT05285501 | Wroclaw University of Health and Sport Sciences | N/A |
| Completed | COVID-19, Patients' Evolution and the Influence of the Pandemic on Health Care and Outcomes in Chronic Disease NCT05168722 | Hospital Galdakao-Usansolo | — |
| Completed | Combined N-of-1 Trials to Assess Open-Label Placebo Treatment for Antidepressant Discontinuation Symptoms NCT05051995 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Completed | Guided Feedback in an Online Game Impacts Decision Making NCT05925816 | Bard College | N/A |
| Completed | Neural Mechanisms of Enhancing Emotion Regulation in Bereaved Spouses NCT04822194 | Bryan Denny | N/A |
| Completed | Written Exposure Therapy for Nurses NCT06432374 | University of Texas at Austin | EARLY_Phase 1 |
| Completed | Physical Exercise and Depressive Symptoms in Moderately or Severely Depressed Adults NCT05703776 | Je Bouge Pour Mon Moral | N/A |
| Recruiting | Cannabidiol for Reduction of Brain Neuroinflammation NCT05066308 | Massachusetts General Hospital | Phase 2 |
| Unknown | Mindful-life: Mindfulness Based Intervention vs Cognitive Behavioral Therapy in Patients With Breast Cancer NCT03972020 | University of Turin, Italy | N/A |
| Completed | Treating Self-criticism in Adolescents: a Study With Single-case Experimental Design NCT05247190 | Region Östergötland | N/A |
| Completed | Mindful Self-Compassion (MSC) for Infertility Related Distress NCT05183568 | University of Regina | Phase 1 / Phase 2 |
| Completed | Health Care Workers and Mental Health NCT05028075 | University of Pennsylvania | N/A |
| Withdrawn | COMET India Follow-up Trial NCT05138120 | University of Pennsylvania | N/A |
| Completed | Effectiveness of a CBT Based Mobile Application NCT05188950 | National Taiwan University Hospital | N/A |
| Completed | The Effectiveness of Culturally Adapted Cognitive Behavioral Intervention Among COVID-19 Survivors NCT04949061 | Koç University | N/A |
| Completed | Twelve Weeks of Resistance Training is Equally As Effective At Improving Cardiovascular Risk Factors in Older NCT06591325 | Universidade Estadual de Londrina | N/A |
| Unknown | RESTORE in Patients Who Had COVID-19 and Close Others NCT04958902 | University Health Network, Toronto | N/A |
| Completed | Evaluation of a Mobile Therapy for Elevated Depressive Symptoms NCT04463914 | Medical University of South Carolina | N/A |
| Completed | Implementation of a Depression Screening Intervention at a Transgender Health Clinic in Thailand NCT05323695 | Thai Red Cross AIDS Research Centre | N/A |
| Unknown | The Efficacy of a Physical Activity Counselling Intervention on Mental Health in Firefighters NCT05061225 | KU Leuven | N/A |
| Completed | The Effect of Instant Message Intervention for Psychological Well-being Among Stroke Survivors NCT05490069 | The University of Hong Kong | N/A |
| Unknown | Transcendental Meditation and PTSD NCT04856033 | David Lynch Foundation | Phase 3 |
| Unknown | Hypertension and Diabetes Assessment in the Rohingya Refugee Population and in the Host Communities in Banglad NCT04307875 | University Hospital Freiburg | — |
| Completed | Testing THRIVE 365 for Black Sexual Minority Men (On The Daily) NCT05376397 | Rutgers, The State University of New Jersey | N/A |
| Unknown | Cognitive Behavioural Therapy for Youths With Depressive and Anxiety Symptoms in Hong Kong NCT05078424 | The University of Hong Kong | N/A |
| Completed | Ecological Momentary Intervention for Stroke Caregivers' Psychological Support NCT04936828 | The University of Hong Kong | N/A |
| Completed | The Effects of Bifidobacterium Longum 1714® in a Population With Low Mood NCT04925440 | PrecisionBiotics Group Ltd. | N/A |
| Terminated | Bright Light Therapy for Depression Symptoms in Adults With Cystic Fibrosis (CF) and COPD NCT04921332 | Erica Osborn | N/A |
| Completed | To Increase Psychological Well-being by the Implementation of Forgiveness Education NCT04403126 | University of Wisconsin, Madison | N/A |
| Completed | HEPPI: Efficacy of a Cognitive-Emotional Intervention for Homebound Older Adults NCT05499767 | University of Coimbra | N/A |
| Completed | Supplementation and Depressive Symptomatology Incidence Among Saudi Arabian Adults NCT05916053 | Lebanese American University | N/A |
| Completed | Behavioral Activation Teletherapy to Increase Physical Activity NCT04990401 | University of Texas Southwestern Medical Center | N/A |
| Completed | Adaptation of a Behavioral Activation Treatment to Treat Depression in Autistic Adults NCT05030610 | Rutgers, The State University of New Jersey | N/A |
| Completed | Implementation Science Approach to Enhancing Depression Treatment in Collaborative Depression Care Settings ( NCT05085886 | Columbia University | N/A |
| Unknown | Brief Nursing Advice for University Students With Depressive Symptoms NCT04966650 | The University of Hong Kong | N/A |
| Unknown | Ecological Momentary Intervention for Depressive Symptoms in a Community Sample in Hong Kong NCT04985422 | The University of Hong Kong | N/A |
| Completed | Improving Depressive Symptoms Through Personalised Exercise and Activation NCT04857944 | Hospital del Mar Research Institute (IMIM) | N/A |
| Recruiting | Reward Processing and Depressive Subtypes: Identifying Neural Biotypes NCT06080646 | San Francisco Veterans Affairs Medical Center | — |
| Completed | Goal2QuitVaping for Nicotine Vaping Cessation Among Adolescents NCT04951193 | Medical University of South Carolina | N/A |
| Completed | Cultivating Resilience in Oncology Practice NCT04902313 | Linkoeping University | Phase 1 |
| Completed | A Self-directed Mobile Mindfulness Intervention to Address Distress and Burnout in Frontline Healthcare Worker NCT04816708 | Duke University | N/A |
| Completed | StriveWeekly Online Mental Health Trial Post-pandemic NCT04927845 | Harvard University | N/A |
| Completed | Investigating Differential Effects of Online Mental Training Interventions on Mental Well-being and Social Coh NCT04889508 | Max Planck Social Neuroscience Lab | N/A |
| Unknown | TreadWill, an Automated Intervention for Depressive Symptoms NCT04703491 | Indian Institute of Technology Kanpur | N/A |
| Completed | Online Cognitive Behavioral Therapy for Depressive Symptoms in Rural Patients with Cardiac Disease NCT04986969 | Debra Moser | N/A |
| Completed | Effectiveness Study of the Intervention "Stop Sexual Harassment" in Secondary School NCT04716400 | NORCE Norwegian Research Centre AS | N/A |
| Completed | Brief Digital CBT for Mood and Anxiety Symptoms in Acute Psychiatric Inpatients NCT04841603 | Centre for Addiction and Mental Health | N/A |
| Completed | Incorporating Stepped Care Approach Into e-CBT for Depression NCT04747873 | Dr. Nazanin Alavi | N/A |
| Unknown | Pregnancy Without Psychosocial Stress NCT04853693 | National Institute of Mental Health, Czech Republic | N/A |
| Completed | The Effects of the Be Mindful Intervention in Previously Depressed Individuals Experiencing Subclinical Sympto NCT04740879 | State University of New York at Buffalo | N/A |
| Recruiting | Psilocybin for Depression in People With Mild Cognitive Impairment or Early Alzheimer's Disease NCT04123314 | Johns Hopkins University | EARLY_Phase 1 |
| Completed | Further Development and Initial Testing of RESTORE in Frontline Workers NCT04873622 | University Health Network, Toronto | N/A |
| Completed | 3-year Follow-up of the Mind My Mind RCT NCT04804917 | Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital | — |
| Completed | Video Feedback to Improve Parental Sensitivity in Mother-infant Dyads With Depressive Symptoms NCT04748731 | Pontificia Universidad Catolica de Chile | N/A |
| Withdrawn | Evaluating an Online Wellness Intervention for Greek Adolescents NCT04815681 | University of Pennsylvania | N/A |
| Completed | Remote Psychological Intervention for COVID-19 Survivors With AKI and Caregivers (REPICOV-AKI) NCT06522776 | Jesus Rivero, MD | N/A |
| Completed | Living Well: A Digital ACT Intervention NCT04787809 | University of Texas at Tyler | N/A |
| Completed | Esketamine and Perioperative Depressive Symptoms NCT04425473 | Beijing Tiantan Hospital | Phase 2 / Phase 3 |
| Completed | Evaluation of an Acceptance and Commitment Therapy-Based Narrative Intervention for Individuals Taking Antidep NCT04757961 | Utah State University | N/A |
| Completed | Stress-reduction Wellness Program for Midlife Black Women (B-SWELL) NCT04404478 | University of Cincinnati | N/A |
| Completed | Researching Resiliency in Stressful Experiences (RISE) Program for Men Leaving Incarceration NCT04785677 | Florida State University | N/A |
| Unknown | Online System for Identifying and Addressing Teen Depression in Primary Care NCT04489485 | Total Child Health, Inc. | — |
| Completed | Group Program vs Single-Session Depathologizing Intervention for Subthreshold Anxiety-Depression in Primary Ca NCT07363915 | University of Alcala | N/A |
| Unknown | Digital Mental Health and Wellness Intervention for Adults: A Randomized Control Trial of COMET NCT04586192 | University of Pennsylvania | N/A |
| Unknown | Cholecalciferol on Depressive Symptoms in Type 2 Diabetes Mellitus Patients NCT04917458 | Indonesia University | Phase 2 |
| Completed | The Relationship of Psychological Factors and Sleep Quality With the Severity of Carpal Tunnel Syndrome NCT05047367 | Cumhuriyet University | — |
| Completed | Web-based Self-help Intervention Promoting Mental Health in Adolescents NCT04994496 | Ludwig-Maximilians - University of Munich | N/A |
| Completed | Web-based Self-help Intervention for Adolescents With Acute or Remitted Major Depressive Disorder NCT04994470 | Ludwig-Maximilians - University of Munich | N/A |
| Unknown | Breath Control and Mindfulness for Post Concussion Anxiety and Depression: a Feasibility Study NCT04708522 | Western University, Canada | N/A |
| Completed | The Acceptability and Effectiveness of Stepped Care Psychoeducation Classes in Rural Manitoba NCT04105790 | University of Manitoba | N/A |
| Completed | Internet-Based Cognitive Behavioral Therapy for Depressive Symptoms in Adolescents With Type 1 Diabetes Mellit NCT03655067 | University of Texas Southwestern Medical Center | N/A |
| Terminated | EMA Baseline Screening System for Therapists Who Treat Youths With Depressive Symptoms NCT04830527 | Vania Martínez-Nahuel | N/A |
| Completed | Brief Video Interventions for Depression NCT04643964 | Ohio State University | N/A |
| Completed | The Delivery of "Doing What Matters in Times of Stress: An Illustrated Guide" NCT04631887 | Koç University | N/A |
| Unknown | Telepsychoeducation for the Prevention of Emotional Distress in Professionals and Students From Essential Serv NCT04632082 | Hospital de Clinicas de Porto Alegre | N/A |
| Completed | Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child Adv NCT04606199 | University of California, San Francisco | N/A |
| Recruiting | Transcranial Magnetic Stimulation for Psychological Distress in Patients With Advanced Illness NCT04257227 | Ottawa Hospital Research Institute | N/A |
| Completed | Responses to Information on Treatments for Depression NCT04639765 | Ohio State University | N/A |
| Completed | The Virtual Reality Therapy as a Pulmonary Rehabilitation Supporting Method NCT04601545 | Wroclaw University of Health and Sport Sciences | N/A |
| Completed | Effect of #LIFEGOALS on Adolescents' Mental Health NCT04719858 | University Ghent | N/A |
| Completed | Evaluating an Online Wellness Intervention for Indian College Students NCT04592588 | University of Pennsylvania | N/A |
| Completed | eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk NCT04437485 | Indiana University | Phase 2 |
| Completed | Evaluation of Mindfulness and Yoga in Basic Combat Training NCT05550610 | Walter Reed Army Institute of Research (WRAIR) | N/A |
| Unknown | Online Mindfulness-Based College for Young Adults NCT04733300 | Eric Loucks | N/A |
| Completed | Mindfulness-based Intervention to Address PTSD in Trauma-exposed, Homeless Women NCT04605198 | University of California, Los Angeles | N/A |
| Completed | Assessment of Stress Levels and Depressive and Anxiety Symptoms in Patients With COPD NCT04726917 | The Opole University of Technology | — |
| Terminated | The Effects of Attention Training on Emotion Regulation and Stress Related Complaints During COVID-19 NCT04367636 | University Ghent | N/A |
| Completed | Effects of Virtual Reality Exercise on Promoting Physical Activity and Health Among College Students NCT06902727 | The University of Tennessee, Knoxville | N/A |
| Completed | Digital Data in Mental Health Therapy NCT04011540 | University of Pennsylvania | N/A |
| Completed | A Systems-Level Intervention for Rural Adults With Depression NCT04502186 | University of Michigan | N/A |
| Completed | Selective Prevention Transdiagnostic Intervention for At-risk Adolescents NCT04851366 | University of Jaén | N/A |
| Completed | Indicated Prevention Transdiagnostic Intervention for Adolescents At High Risk of Emotional Problems NCT05252026 | University of Jaén | N/A |
| Terminated | Treatment of Depressive Symptoms in Older Individuals in Isolation During Covid-19 NCT04508868 | Uppsala University | N/A |
| Enrolling By Invitation | Youth Depression and Suicide Research Network NCT04572321 | University of Texas Southwestern Medical Center | — |
| Completed | Transdiagnostic Treatment for Emotional Disorders NCT04498949 | Mohamad hasan yousefi | N/A |
| Completed | Attachment and Biobehavioral Catch-up for Depression NCT04050202 | University of California, San Francisco | N/A |
| Completed | The Effect of Emotional Freedom Technique on Depression, Anxiety and Distress of Individuals With Multiple Scl NCT04969562 | Dokuz Eylul University | N/A |
| Completed | Towards a Better Understanding of Diabetes Distress, Depression and Poor Glycaemic Control in T2DM NCT04438018 | Norbert Hermanns | — |
| Unknown | Brief Cognitive Behavioral Therapy Versus Crisis Intervention Therapy Through Telepsychiatry on Psychiatric Sy NCT04394455 | Universidad Nacional Autonoma de Honduras | N/A |
| Unknown | Do Network Centrality Predict Overall Depression Symptom Reduction With Lifting of Social Distancing Protocols NCT04444713 | Modum Bad | — |
| Unknown | Perioperative Cognitive Trajectories in Deferred Surgery (CoTELE-SURGE) NCT04787536 | McMaster University | — |
| Unknown | Efficacy of Therapist Guided e-Therapy Versus Self-Help Therapy on Psychological Distress Among Individuals in NCT04378257 | Sultan Qaboos University | Phase 3 |
| Completed | Homebound Elderly People Psychotherapeutic Intervention NCT04967378 | University of Coimbra | N/A |
| Withdrawn | Keeping Well:Online Cognitive Behavioral Therapy (CBT) for Pregnant Women With Depressive Symptoms NCT01909167 | Imperial College London | N/A |
| Completed | Mindfulness and Intercare Based Intervention for Medicine Students (MIIM) NCT05011955 | University Diego Portales | N/A |