| Not Yet Recruiting | Coordinated Reset Deep Brain Stimulation for Parkinson's Disease NCT07340073 | University of Minnesota | Phase 1 |
| Not Yet Recruiting | Neural Mechanisms of Aerobic Exercise Benefits in PD With DBS NCT07442747 | The Cleveland Clinic | N/A |
| Not Yet Recruiting | Safety and Tolerability of Patterned Stimulation for DBS in the Home Setting NCT07410598 | University of Florida | N/A |
| Not Yet Recruiting | Comparing Biomarker-Guided DBS Programming With Standard Clinical Monopolar Programming NCT07369310 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | N/A |
| Recruiting | Predictors of Clinical Outcomes of Deep Brain Stimulation in Parkinson's Disease NCT07376278 | Hong Kong University of Science and Technology | — |
| Recruiting | Adaptive vs. Continuous Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease NCT06909045 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Recruiting | A Study of Buntanetap in Participants With PD NCT07284784 | Annovis Bio Inc. | Phase 2 / Phase 3 |
| Recruiting | LIFUS For Neurological Disorders NCT07417280 | University Health Network, Toronto | N/A |
| Recruiting | Testing of an Interface for Synchronizing tACS-DBS With a Phase-locked-loop NCT07139093 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Recruiting | Effect of Mediterranean Diet on Nutrition in Parkinson's Disease Patients With Bilateral Subthalamic Deep Brai NCT07187739 | Ankara University | N/A |
| Recruiting | Revision of Deep Brain Stimulator in Patients With Parkinson's Disease NCT07176494 | Ankara Etlik City Hospital | N/A |
| Not Yet Recruiting | Consensus Statements on Deep Brain Stimulation in Patients With Parkinson's Disease NCT07173660 | University Magna Graecia | — |
| Not Yet Recruiting | VC/VS for Apathy in PD NCT06991335 | Nora Vanegas | N/A |
| Recruiting | Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study NCT06960096 | Medical University of South Carolina | — |
| Recruiting | EEG Measurements to Capture DBS-induced Electric Potentials NCT07115394 | Universitätsklinikum Hamburg-Eppendorf | — |
| Not Yet Recruiting | One-Year Effect on Levodopa Equivalent Daily Dose of Thalamic VIM Nucleus Stimulation Compared to Subthalamic NCT06936254 | Central Hospital, Nancy, France | — |
| Recruiting | Imaging Biomarkers of FOG Response to DBS NCT06951906 | Medical University of South Carolina | Phase 4 |
| Recruiting | Evaluating Modulation Effects of Temporal Interference Using SEEG NCT06663969 | Xuanwu Hospital, Beijing | N/A |
| Recruiting | Impact of Frequency-specific Subthalamic Nucleus Subregion Stimulation on Inhibitory Control in Parkinson's Di NCT07022522 | Beijing Tiantan Hospital | N/A |
| Recruiting | Multitarget Stereotactic Electrophysiological Recording and Stimulation for Tourette Syndrome NCT06889480 | Beijing Tiantan Hospital | N/A |
| Recruiting | Neural Mechanisms and Clinical Applications of DBS for Modulating Sleep Dysregulation in PD NCT06914466 | Xuanwu Hospital, Beijing | — |
| Recruiting | Esketamine in Microelectrode Recording-guided Subthalamic Deep-Brain Stimulation for Parkinson's Disease NCT06543563 | Beijing Tiantan Hospital | N/A |
| Recruiting | A Multicenter Pediatric Deep Brain Stimulation Registry NCT06585618 | Boston Children's Hospital | — |
| Completed | Dual-task Augmented Reality for PD DBS NCT06418152 | Jay Alberts | N/A |
| Recruiting | The BRAINMAP-DBS Study: BRain Network AnalysIs usiNg 7-Tesla MRI and MAgnetoencephalograPhy for Deep Brain Sti NCT06932692 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Recruiting | Udall Project 1 Aim 4 NCT05568199 | University of Minnesota | — |
| Completed | Evaluation of Advanced Imaging and Visualization for Clinical Deep Brain Stimulation NCT06191874 | Duke University | — |
| Recruiting | Multicentre RCT of Awake Versus Asleep Tractography Based DBS for ET NCT05968976 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Unknown | DBS Imaging-based vs. Threshold Assessment-based Programming NCT06223399 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Recruiting | Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia NCT07325175 | Children's Hospital Medical Center, Cincinnati | N/A |
| Unknown | Dexmedetomidine Prevents Postoperative Delirium After Deep Brain Stimulation in Patients With Parkinson's Dise NCT05197439 | Beijing Tiantan Hospital | N/A |
| Not Yet Recruiting | Safety and Efficacy Study of Implantable Neuromodulation for Poststroke Hemiplegia NCT06121947 | Chinese PLA General Hospital | N/A |
| Enrolling By Invitation | The Relation Between the Prognosis of Subthalamic Nucleus Deep Brain Stimulation Surgery by Microlesion Effect NCT06685510 | Second Affiliated Hospital of Nanchang University | — |
| Unknown | Remote Programming for Deep Brain Stimulation in Parkinson's Disease. NCT06078397 | Ruijin Hospital | N/A |
| Terminated | Visualization of the STN and GPi for DBS NCT05774041 | Surgical Information Sciences Inc. | — |
| Recruiting | Efficacy and Safety of Combo-stim Deep Brain Stimulation for Treatment-refractory Mental Disorders NCT06112067 | Shanghai Mental Health Center | N/A |
| Recruiting | Optimization of Deep Brain Stimulation Parameters in Patients With Medically Refractory Epilepsy NCT05493722 | University of Minnesota | EARLY_Phase 1 |
| Active Not Recruiting | Deep Brain Stimulation Recovery in Treatment-Resistant Schizophrenia NCT05337904 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | N/A |
| Completed | The Impact of Exercise on Subthalamic Nucleus Neural Activity in Parkinson's Disease NCT05905302 | Jay Alberts | N/A |
| Unknown | Efficacy and Safety of Dual-target Deep Brain Stimulation for Treatment-resistant Alcohol Use Disorder NCT05884619 | Second Xiangya Hospital of Central South University | N/A |
| Not Yet Recruiting | Study on Brain Network Mechanism of Deep Brain Stimulation for Parkinson's Disease NCT05959161 | Tianjin Huanhu Hospital | — |
| Unknown | Efficacy and Safety of Dual-target DBS for Treatment-resistant Alcohol Use Disorder NCT05786872 | Shanghai Mental Health Center | N/A |
| Recruiting | Sleep-specific DBS Therapy in Parkinson's Disease NCT05962489 | University of Minnesota | N/A |
| Unknown | Programming Strategy of VFS for Gait Impairments in PD NCT05905198 | Peking Union Medical College Hospital | N/A |
| Unknown | Subgenual Cingulate Deep Brain STIMulation for Apathetic Behavioral Variant FRONtotemporal Dementia NCT05699330 | University Health Network, Toronto | N/A |
| Recruiting | Choice of Anesthesia in Microelectrode Recording Guided Deep Brain Stimulation for Parkinson's Disease NCT05550714 | Beijing Tiantan Hospital | N/A |
| Recruiting | Low Intensity Focused Ultrasound for Mild Cognitive Impairment and Mild Alzheimer's Disease NCT05417555 | University of California, Los Angeles | N/A |
| Terminated | Burst-Type Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease NCT05753449 | Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute) | N/A |
| Completed | Deep Brain Stimulation in Tourette Syndrome NCT06388291 | University College, London | N/A |
| Completed | Utilizing Neural Signatures and Virtual Reality to Advance DBS Programming NCT05103384 | The Cleveland Clinic | — |
| Recruiting | Deep Brain Stimulation for Idiopathic Craniofacial Dystonia: GPi or STN NCT05416905 | Beijing Tiantan Hospital | N/A |
| Recruiting | Use of CereGate Therapy for Freezing of Gait in PD NCT05292794 | CereGate Inc. | N/A |
| Recruiting | The STEREO-DBS Study: 7-Tesla MRI Brain Network Analysis for Deep Brain Stimulation NCT05843084 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Completed | Evaluation of Remote DBS Programming. NCT05193825 | Thomas Köglsperger | N/A |
| Recruiting | Dystonia Image-based Programming of Stimulation: A Prospective, Randomized, Double-blind Crossover Trial NCT05097001 | Wuerzburg University Hospital | N/A |
| Recruiting | Understanding Motivation in Parkinson's Patients Through Neurophysiology NCT05065151 | University of California, San Francisco | N/A |
| Active Not Recruiting | Enhancing Gait Using Alternating-Frequency DBS in Parkinson Disease NCT05022147 | James Liao | Phase 1 |
| Unknown | Predictive Value of Multimodal MRI in Parkinson's Disease NCT05003206 | Chinese PLA General Hospital | N/A |
| Unknown | Deep Brain Stimulation of the Lateral Hypothalamus to Augment Motor Function of Patients With Spinal Cord Inju NCT04965727 | Jocelyne Bloch | N/A |
| Terminated | Apraxia in Parkinson's Disease Patients With Deep Brain Stimulation NCT04725773 | University of Florida | — |
| Completed | Cortical Network Modulation by Subthalamic Nucleus DBS NCT04922411 | Washington University School of Medicine | N/A |
| Unknown | Deep Brain Stimulation Therapy and Intestinal Microbiota NCT04855344 | The First Affiliated Hospital with Nanjing Medical University | — |
| Unknown | The Efficacy and Prediction of Deep Brain Stimulation for Treatment-resistant Depression NCT04530942 | Ruijin Hospital | N/A |
| Completed | Association Between Fibrinogen-to-albumin Ratio and Delirium After Deep Brain Stimulation Surgery in Parkinson NCT05833308 | Changhai Hospital | — |
| Completed | Ketamine in Deep Brain Stimulation (DBS) Surgery NCT04716296 | Rabin Medical Center | N/A |
| Unknown | Deep Brain Stimulation for Alzheimer's Disease NCT03959124 | Buddhist Tzu Chi General Hospital | N/A |
| Completed | Unilateral GPi vs Unilateral STN DBS in the Same Patient With PD NCT04255719 | Ruijin Hospital | N/A |
| Unknown | Deep Brain Stimulation Treatment for Chorea in Huntington's Disease NCT04244513 | Beijing Municipal Administration of Hospitals | N/A |
| Unknown | The Efficacy and Mechanism of DBS in VIC and NAcc for Refractory OCD NCT04228744 | Ruijin Hospital | N/A |
| Active Not Recruiting | Can Subthalamic Stimulation Using Directional Electrodes Improve Postoperative Management in Parkinson's Disea NCT04578678 | Insel Gruppe AG, University Hospital Bern | — |
| Unknown | Predicting Cognition After DBS for Parkinson's Disease NCT03982953 | Charite University, Berlin, Germany | — |
| Terminated | SIS Evaluation of the MRI Defined Subthalamic Nucleus* NCT03907319 | Surgical Information Sciences Inc. | — |
| Unknown | Interactions of Brain Regions in Visuomotor Adaptation NCT04190940 | University of Virginia | N/A |
| Terminated | Ataxia in Essential Tremor: Describing the Differences Between Disease Process and Treatment Effect NCT03769961 | Oregon Health and Science University | — |
| Completed | Probabilistic Targeting of the VIM NCT03696420 | University Hospital, Bordeaux | — |
| Completed | Deep Brain Stimulation with LIFUP for Mild Cognitive Impairment and Mild Alzheimer's Disease NCT03347084 | University of California, Los Angeles | N/A |
| Unknown | Relief From Side Effects: Clinical Use of Electrodes With Direction NCT03795935 | University of British Columbia | N/A |
| Unknown | Comparison of Outcomes in Asleep and Awake DBS With a Directional Electrode NCT04287465 | Hospital District of Helsinki and Uusimaa | — |
| Terminated | Evaluation of the Benefit Provided by Sessions of Sophrology on the Per Operative Management of Parkinsonian P NCT03273816 | Rennes University Hospital | N/A |
| Unknown | Intrawound Vancomycin Prophylaxis for Neural Stimulator NCT03221023 | University of British Columbia | Phase 2 / Phase 3 |
| Unknown | Dexmedetomidine on Basal Ganglia Neuronal Activity in Parkinson's Disease NCT02982512 | Clinica Universidad de Navarra, Universidad de Navarra | Phase 4 |
| Completed | Validation of HaGuide Software Module Accuracy in Mapping STN Boundaries in Parkinson's Disease Patients Who U NCT03363724 | Alpha Omega Engineering Ltd. | — |
| Completed | The Effectiveness of Alternating Stimulation in Preventing Tolerance in Essential Tremor Patients NCT02947841 | Oregon Health and Science University | N/A |
| Completed | Deep Brain Stimulation for Voice Tremor: Left, Right, or Both Hemispheres? NCT02960243 | University of British Columbia | N/A |
| Completed | Music-listening During Deep Brain Stimulation to Relieve Anxiety NCT03091335 | Darlene A. Lobel, MD | N/A |
| Completed | EC50 of Anesthetics During Microelectric Recording NCT03213912 | Taipei Veterans General Hospital, Taiwan | — |
| Completed | Thalamic Deep Brain Stimulation for Spasmodic Dysphonia- DEBUSSY Trial NCT02558634 | University of British Columbia | N/A |
| Completed | Tandem DBS for Parkinson's Disease: A Pilot Study Utilizing STN/GPi + Hypothalamic Stimulation NCT01563341 | Mayo Clinic | N/A |
| Unknown | Prospective Study to Compare Results of STN-DBS Between Early Treated and Late-treated PD Patient NCT01274832 | A.O. Ospedale Papa Giovanni XXIII | — |
| Unknown | The Effect of Electrode Implantation for Deep Brain Stimulation (DBS) on Brain Function Using Single Photon Em NCT01037686 | Sheba Medical Center | N/A |
| Completed | Implantable Systems Performance Registry NCT00959296 | MedtronicNeuro | — |