NCT07139093

Testing of an Interface for Synchronizing tACS-DBS With a Phase-locked-loop

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 2 (estimated)
• Sponsor: Universitätsklinikum Hamburg-Eppendorf · Academic / Other
• Sex: All
• Age: 35 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The investigators aim to test an interface to phase-lock transcranial alternating current stimulation (tACS) and deep brain stimulation (DBS) for future studies investigating the effects of different time-lags between DBS and tACS on the behavioural and neural level. To test if the interface works in patients with DBS, the investigators record EEG during synchronized tACS-DBS in several patients. The investigators hypothesize that they can apply tACS at the desired phase-lags relative to DBS pulses and confirm this with EEG measurements of the DBS and tACS artifact.

Conditions

• Deep Brain Stimulation
• Parkinson's Disease (PD)

Interventions

Type	Name	Description
DEVICE	DBS-coupled tACS	tACS will be applied in a phase-coupled manner, so that tACS and DBS are synchronized

Timeline

• Start date: 2025-09-30
• Primary completion: 2026-08-01
• Completion: 2026-12-01
• First posted: 2025-08-24
• Last updated: 2026-04-03

Locations

1 site across 1 country: Germany